Spots Global Cancer Trial Database for Study of Target-Guided Chemotherapy in Metastatic Colorectal Patients
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Trial Identification
Brief Title: Study of Target-Guided Chemotherapy in Metastatic Colorectal Patients
Official Title: A Phase 2 Study of Target-Guided Personalized Chemotherapy in Metastatic Colorectal Cancer Patients
Study ID: NCT01453257
Conditions
Interventions
Study Description
Brief Summary: Treatment options for patients with colorectal cancer (CRC) have increased in the last years. However, there are no validated prospective molecular markers in CRC to select which agents are better to treat any individual case. The conventional first-line treatment in CRC patients in clinical studies get a proportion of patients free of progression at 12 months ranging from 35-40% with a median of 9 months of free disease progression. The aim of this study is to demonstrate that the identification of therapeutic targets in real time and their prospectively use to customize the treatment get a proportion of colorectal metastatic patients patients free of progression disease at 12 months of 50%.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Centro Integral Oncológico Clara campal, Madrid, , Spain
Contact Details
Name: Antonio Cubillo, Md PhD
Affiliation: Grupo Hospital madrid
Role: PRINCIPAL_INVESTIGATOR
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