Spots Global Cancer Trial Database for progression free survival
Every month we try and update this database with for progression free survival cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment | NCT00839111 | Colorectal Neop... | sorafenib FOLFIRI | 18 Years - 75 Years | Fudan University | |
| Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer | NCT05185947 | Gynecologic Can... Gynecologic Neo... Peritoneal Carc... Peritoneal Neop... Ovarian Cancer Ovarian Neoplas... Colorectal Canc... Colorectal Neop... Appendiceal Can... Appendiceal Neo... | Paclitaxel Nilotinib | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Cabozantinib in Advanced Salivary Gland Cancer Patients | NCT03729297 | Salivary Gland ... | Cabozantinib | 18 Years - | Radboud University Medical Center | |
| Determination of Immune Phenotype in Glioblastoma Patients | NCT02751138 | Glioblastoma Mu... | Surgery | 18 Years - | University of Ulm | |
| Study of MK 2206 in Patients With Relapsed or Refractory Diffuse Large B Cell Lymphoma | NCT01466868 | Diffuse Large B... | MK2206 | 18 Years - 90 Years | Centre Leon Berard | |
| Safety and Efficacy of Belinostat When Used With Standard of Care Chemotherapy for Untreated Non-small Cell Lung Cancer | NCT01090830 | Non-Small-Cell ... | Belinostat, car... | 18 Years - | Holy Cross Hospital, Florida | |
| Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal Cancer | NCT03542877 | Colorectal Canc... | Oral Tablet: Ca... | 18 Years - 99 Years | University of Colorado, Denver | |
| Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) | NCT01471444 | Disorder Relate... Leukemia Transplantation... | Fludarabine Clofarabine Busulfan Thymoglobulin Stem Cell Infus... Tacrolimus Methotrexate | 3 Years - 70 Years | M.D. Anderson Cancer Center | |
| CTLA-4 Blockade and Low Dose Cyclophosphamide in Patients With Advanced Malignant Melanoma | NCT01740401 | Melanoma | Cyclophosphamid... | 18 Years - | Icahn School of Medicine at Mount Sinai | |
| Safety and Efficacy of Belinostat When Used With Standard of Care Chemotherapy for Untreated Non-small Cell Lung Cancer | NCT01090830 | Non-Small-Cell ... | Belinostat, car... | 18 Years - | Holy Cross Hospital, Florida | |
| Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer | NCT01523457 | Metastatic Panc... Pancreatic Canc... | Folfirinox | 18 Years - | Yale University | |
| Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer | NCT03976843 | Prostate Cancer | 18F-DCFPyL | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics) | NCT02013297 | Brain Metastasi... Spinal Tumors Lung Tumors Ependymoma | SBRT treatment | 18 Months - 20 Years | Centre Leon Berard | |
| Cabozantinib in Advanced Salivary Gland Cancer Patients | NCT03729297 | Salivary Gland ... | Cabozantinib | 18 Years - | Radboud University Medical Center | |
| Efficacy of FOLFOX Alone, FOLFOX Plus Bevacizumab and FOLFOX Plus Panitumumab in Patients With Resectable Liver Metastases | NCT01508000 | Colorectal Canc... Liver Metastase... KRAS Wild Type ... | FOLFOX6 Bevacizumab Panitumumab Surgery | 18 Years - 75 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) | NCT01471444 | Disorder Relate... Leukemia Transplantation... | Fludarabine Clofarabine Busulfan Thymoglobulin Stem Cell Infus... Tacrolimus Methotrexate | 3 Years - 70 Years | M.D. Anderson Cancer Center | |
| Minitransplants With HLA-matched Donors : Comparison Between 2 GVHD Prophylaxis Regimens | NCT01428973 | Graft-Versus-Ho... Hematological M... | Mycophenolate m... Sirolimus | 16 Years - 75 Years | University of Liege | |
| HDR Brachytherapy as Monotherapy for Low and Intermediate Risk Prostate Cancer | NCT03424694 | Prostate Cancer | HDR brachythera... | 18 Years - 85 Years | CR-CSSS Champlain-Charles-Le Moyne | |
| Breast Cancer Study: Paclitaxel Versus Paclitaxel Plus Sorafenib in Second- or Third-line Treatment | NCT01320111 | Metastatic Brea... | Paclitaxel and ... Paclitaxel | 18 Years - | Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH | |
| Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer | NCT01523457 | Metastatic Panc... Pancreatic Canc... | Folfirinox | 18 Years - | Yale University | |
| Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis | NCT04034251 | Gastric Adenoca... Gastric Cancer Esophagogastric... Peritoneal Carc... | Paclitaxel Capecitabine BardPort Titani... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| A Clinical Study Conducted in Multiple Centers Comparing Veliparib in Combination With Carboplatin and Paclitaxel Versus a Placebo in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer | NCT01560104 | Non-Small -Cell... | Veliparib Carboplatin paclitaxel placebo | 18 Years - 99 Years | AbbVie | |
| Almonertinib Plus Microwave Ablation in Advanced Non-small Cell Lung Cancer | NCT04755738 | Advanced Non Sm... | Almonertinib pl... | 18 Years - 80 Years | Qianfoshan Hospital | |
| Palliative Treatment With Liposomal Doxorubicin Plus Cisplatin for Patients With Malignant Pleural Mesothelioma | NCT00886028 | Malignant Pleur... | Liposomal doxor... Cisplatin | 18 Years - 80 Years | National Institute of Cancerología | |
| Study to Compare Zoladex™ 10.8 mg With Zoladex 3.6 mg in Pre-menopausal Women With Breast Cancer | NCT01073865 | Breast Cancer | ZD9393 (Zoladex... ZD9393 (Zoladex... | 20 Years - 130 Years | AstraZeneca | |
| Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome | NCT04754672 | Colorectal Canc... Chemotherapeuti... Survivorship Lifestyle | Continuous aero... Continuous aero... | 18 Years - | Radboud University Medical Center | |
| A Clinical Study Conducted in Multiple Centers Comparing Veliparib in Combination With Carboplatin and Paclitaxel Versus a Placebo in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer | NCT01560104 | Non-Small -Cell... | Veliparib Carboplatin paclitaxel placebo | 18 Years - 99 Years | AbbVie | |
| HDR Brachytherapy as Monotherapy for Low and Intermediate Risk Prostate Cancer | NCT03424694 | Prostate Cancer | HDR brachythera... | 18 Years - 85 Years | CR-CSSS Champlain-Charles-Le Moyne | |
| Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity Conditioning | NCT03852407 | Acute Myeloid L... Myelodysplastic... Chronic Myeloid... Myeloproliferat... Myeloproliferat... Acute Lymphoid ... Multiple Myelom... Chronic Lymphoi... Non Hodgkin Lym... Hodgkin Lymphom... | Thymoglobulin Melphalan Fludarabine Cyclophosphamid | 18 Years - 75 Years | University of Liege | |
| Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC). | NCT04566133 | Bile Duct Cance... Biliary Cancer Biliary Tract N... Cholangiocarcin... | Trametinib Hydroxychloroqu... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Survival With Olanzapine in Patients With Locally Advanced or Metastatic Upper Gastrointestinal and Lung Cancer | NCT06338683 | Advanced Cancer Olanzapine Progression Fre... | Olanzapine 2.5 ... Standard anti-t... Nutritional adv... | 18 Years - 80 Years | Qinghai Red Cross Hospital | |
| Intraperitoneal and Intravenous Paclitaxel Chemotherapy With Oral Capecitabine for Gastric Adenocarcinoma With Peritoneal Carcinomatosis | NCT04034251 | Gastric Adenoca... Gastric Cancer Esophagogastric... Peritoneal Carc... | Paclitaxel Capecitabine BardPort Titani... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Study of the Combination Carboplatin Plus Celecoxib in Heavily Pre-treated Recurrent Ovarian Cancer Patients | NCT01124435 | Ovarian Neoplas... | Carboplatin plu... | 18 Years - 75 Years | Catholic University of the Sacred Heart | |
| Almonertinib Plus Microwave Ablation in Advanced Non-small Cell Lung Cancer | NCT04755738 | Advanced Non Sm... | Almonertinib pl... | 18 Years - 80 Years | Qianfoshan Hospital | |
| Osimertinib or Docetaxel-bevacizumab as Third-line Treatment in EGFR T790M Mutated Non-Small Cell Lung Cancer | NCT02959749 | Progression Fre... | Osimertinib docetaxel, beva... | 18 Years - 80 Years | Qingdao Central Hospital | |
| Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Carcinoma | NCT05032092 | Locally Advance... Metastatic Canc... | Next Generation... Next Generation... Biomarker Monit... | 18 Years - | Medical University of Graz | |
| Study of Target-Guided Chemotherapy in Metastatic Colorectal Patients | NCT01453257 | Progression Fre... | Tailored Chemot... | 18 Years - 80 Years | Grupo Hospital de Madrid | |
| A Randomized Study to Determine the Efficacy of a Taxane and Bevacizumab With or Without Capecitabine as First Line Chemotherapy in Patients With Metastatic Breast Cancer | NCT01200212 | Breast Cancer | Taxane, Avastin Taxane, Avastin... | 18 Years - | German Breast Group | |
| DIAGNOSIS, TREATMENT AND OUTCOME OF LUNG CANCER PATIENTS | NCT05254119 | Non Small Cell ... Small-cell Lung... | 18 Years - | Oncological Clinical Research Association, Turkey | ||
| Evaluation of Efficacy of Comprehensive Genomic Tumour Profiling (CGP) From Liquid and/or Tissue Biopsy in Patients With Locally Advanced and/or Metastatic Carcinoma | NCT05032092 | Locally Advance... Metastatic Canc... | Next Generation... Next Generation... Biomarker Monit... | 18 Years - | Medical University of Graz | |
| A Clinical Study Conducted in Multiple Centers Comparing Veliparib in Combination With Carboplatin and Paclitaxel Versus a Placebo in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer | NCT01560104 | Non-Small -Cell... | Veliparib Carboplatin paclitaxel placebo | 18 Years - 99 Years | AbbVie | |
| BENdamustine at Elevated Dose for Relapsed Follicular Lymphoma in Intensification Therapy and Transplantation (BENEFIT) | NCT02008006 | Follicular Lymp... | BeEAM | 18 Years - 65 Years | Centre Leon Berard | |
| A Clinical Study Conducted in Multiple Centers Comparing Veliparib in Combination With Carboplatin and Paclitaxel Versus a Placebo in Combination With Carboplatin and Paclitaxel in Patients With Advanced Non-small Cell Lung Cancer | NCT01560104 | Non-Small -Cell... | Veliparib Carboplatin paclitaxel placebo | 18 Years - 99 Years | AbbVie | |
| BENdamustine at Elevated Dose for Relapsed Follicular Lymphoma in Intensification Therapy and Transplantation (BENEFIT) | NCT02008006 | Follicular Lymp... | BeEAM | 18 Years - 65 Years | Centre Leon Berard | |
| Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer | NCT03976843 | Prostate Cancer | 18F-DCFPyL | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Bendamustine Plus Rituximab Versus CHOP Plus Rituximab | NCT00991211 | Non-Hodgkin Lym... Follicular Lymp... Immunocytomas Lymphocytic Lym... Marginal Zone L... | Bendamustine Standard chemot... | 18 Years - | University of Giessen | |
| Phase 2 Study With Abraxane (Nab®Paclitaxel) in Metastatic Colorectal Cancer | NCT02103062 | Colorectal Neop... | ABI-007 | 18 Years - | Celgene | |
| Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With Colorec | NCT01116271 | Colorectal Canc... | AZD6244 Irinotecan | 18 Years - | AstraZeneca | |
| Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC). | NCT04566133 | Bile Duct Cance... Biliary Cancer Biliary Tract N... Cholangiocarcin... | Trametinib Hydroxychloroqu... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Efficacy of FOLFOX Versus FOLFOX Plus Aflibercept in K-ras Mutant Patients With Resectable Liver Metastases | NCT01646554 | Colorectal Canc... Liver Metastase... KRAS Mutated Co... | Modified FOLFOX... Aflibercept Surgery | 18 Years - 75 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Clinico-biological Data Collection Study of Metastatic Breast Cancer | NCT03958136 | Breast Cancer | Metastasis biop... Biomarkers bloo... Patient Reporte... | 18 Years - | Institut Cancerologie de l'Ouest | |
| CTLA-4 Blockade and Low Dose Cyclophosphamide in Patients With Advanced Malignant Melanoma | NCT01740401 | Melanoma | Cyclophosphamid... | 18 Years - | Icahn School of Medicine at Mount Sinai | |
| Study of Gemcitabine Maintenance Treatment in Patients With Extensive SCLC Patients | NCT02039518 | Small Cell Lung... | gemcitabine observation gro... | 18 Years - | Fudan University | |
| Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients | NCT01129336 | First or Second... Metastatic Dise... | Zoledronic acid Standard Therap... | 18 Years - | Novartis | |
| Microwave Ablation in Combination With Camrelizumab Versus Camrelizumab in Metastatic Non-small-cell Lung Cancer | NCT04102982 | NSCLC Stage IV | Camrelizumab Camrelizumab pl... | 18 Years - 80 Years | Shandong Provincial Hospital | |
| Almonertinib Plus Microwave Ablation in Advanced Non-small Cell Lung Cancer | NCT04755738 | Advanced Non Sm... | Almonertinib pl... | 18 Years - 80 Years | Qianfoshan Hospital | |
| Neoadjuvant Triple Treatment for Borderline Resectable Pancreatic Cancer (PREOPANC-5) | NCT06384560 | Borderline Rese... | Pembrolizumab | 18 Years - | Amsterdam UMC, location VUmc | |
| Osimertinib or Docetaxel-bevacizumab as Third-line Treatment in EGFR T790M Mutated Non-Small Cell Lung Cancer | NCT02959749 | Progression Fre... | Osimertinib docetaxel, beva... | 18 Years - 80 Years | Qingdao Central Hospital | |
| Sorafenib and FOLFIRI Regimen in 2nd Colorectal Cancer (CRC) After Failure of Oxaliplatin Treatment | NCT00839111 | Colorectal Neop... | sorafenib FOLFIRI | 18 Years - 75 Years | Fudan University | |
| Efficacy and Safety of Cetuximab in Metastatic Penile Carcinoma (PENILANE) | NCT02014831 | Squamous Cell C... | Cetuximab TIP | 18 Years - | Centre Leon Berard | |
| IMPROVE Intervention Trial Implementing Non-invasive Circulating Tumor DNA Analysis to Optimize the Operative and Postoperative Treatment for Patients With Colorectal Cancer | NCT03748680 | Colorectal Canc... Circulating Tum... Adjuvant Chemot... Progression Fre... | Capox (or FOLFO... Intensified Fol... | 18 Years - | Aarhus University Hospital | |
| Palliative Treatment With Liposomal Doxorubicin Plus Cisplatin for Patients With Malignant Pleural Mesothelioma | NCT00886028 | Malignant Pleur... | Liposomal doxor... Cisplatin | 18 Years - 80 Years | National Institute of Cancerología | |
| R-CDOP Combined With Intrathecal Methotrexate for DLBCL Patients With High-risk of CNS Relapse | NCT05257018 | Diffuse Large B... | R-CDOP+intrathe... | 18 Years - 75 Years | Fudan University | |
| IMPROVE Intervention Trial Implementing Non-invasive Circulating Tumor DNA Analysis to Optimize the Operative and Postoperative Treatment for Patients With Colorectal Cancer | NCT03748680 | Colorectal Canc... Circulating Tum... Adjuvant Chemot... Progression Fre... | Capox (or FOLFO... Intensified Fol... | 18 Years - | Aarhus University Hospital | |
| Breast Cancer Study: Paclitaxel Versus Paclitaxel Plus Sorafenib in Second- or Third-line Treatment | NCT01320111 | Metastatic Brea... | Paclitaxel and ... Paclitaxel | 18 Years - | Gesellschaft fur Medizinische Innovation - Hamatologie und Onkologie mbH | |
| Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal Cytology | NCT03092518 | Gastric Adenoca... Esophagogastric... Gastric Cancer | Surgery Cisplatin Mitomycin C Sodium Thiosulf... | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Determination of Immune Phenotype in Glioblastoma Patients | NCT02751138 | Glioblastoma Mu... | Surgery | 18 Years - | University of Ulm | |
| Clinico-biological Data Collection Study of Metastatic Breast Cancer | NCT03958136 | Breast Cancer | Metastasis biop... Biomarkers bloo... Patient Reporte... | 18 Years - | Institut Cancerologie de l'Ouest | |
| Effect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer Patients | NCT01129336 | First or Second... Metastatic Dise... | Zoledronic acid Standard Therap... | 18 Years - | Novartis | |
| A Web-mediated Follow-up With the Web-application KidneyPRO Versus Standard Follow-up for Patients With Advanced Renal Cell Carcinoma Treated With Axitinib/Pembrolizumab in First Line | NCT04764487 | Renal Cell Carc... | KidneyPRO standard follow... | 18 Years - | Weprom |
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