Spots Global Cancer Trial Database for Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
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Trial Identification
Brief Title: Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC
Official Title: TALAPRO-3: A PHASE 3, RANDOMIZED, DOUBLE-BLIND, STUDY OF TALAZOPARIB WITH ENZALUTAMIDE VERSUS PLACEBO WITH ENZALUTAMIDE IN MEN WITH DDR GENE MUTATED METASTATIC CASTRATION-SENSITIVE PROSTATE CANCER
Study ID: NCT04821622
Conditions
Study Description
Brief Summary: The purpose of the study is to evaluate the safety and efficacy of talazoparib in combination with enzalutamide compared with placebo in combination with enzalutamide in participants with DDR-deficient mCSPC.
Detailed Description: The study will have 5 periods: prescreening, screening, double-blind treatment, safety follow-up, and long-term follow-up. Approximately 550 men with mCSPC will be randomized. Eligible participants will be randomly assigned to either of 2 treatment groups as follows: * Talazoparib in combination with enzalutamide. * Placebo capsules identical in appearance to talazoparib capsules in combination with enzalutamide. Talazoparib or identical placebo treatment will be blinded. Enzalutamide (160 mg/day) will be open label. The dose of talazoparib/placebo to be given in combination with enzalutamide is 0.5 mg once daily. Participants with moderate renal impairment (eGFR 30-59 mL/min/1.73 m2 by the MDRD equation) at screening may be enrolled and the talazoparib/placebo dose will be 0.35 mg once daily.
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
University of Alabama at Birmingham, Birmingham, Alabama, United States
University of Alabama at Birmingham, Birmingham, Alabama, United States
Arizona Institute of Urology, PLLC, Tucson, Arizona, United States
Beverly Hills Cancer Center, Beverly Hills, California, United States
Adventist Health Glendale, Glendale, California, United States
VA Long Beach Healthcare System, Long Beach, California, United States
Yale-New Haven Hospital, New Haven, Connecticut, United States
MedStar Georgetown University Hospital, Washington, District of Columbia, United States
Washington Cancer Institute at MedStar Washington Hospital Center, Washington, District of Columbia, United States
AdventHealth Medical Group Hematology and Oncology, Orlando, Florida, United States
Investigational Drug Services, Advent Health Orlando, Orlando, Florida, United States
Investigational Drug Services, Orlando, Florida, United States
Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Austell, Georgia, United States
Wellstar Cobb Hospital, Austell, Georgia, United States
Northwest Georgia Oncology Centers, a Service of Tanner Medical Center Villa Rica, Carrollton, Georgia, United States
West Georgia Infusion Center, a Service of Tanner Medical Center Villa Rica, Carrollton, Georgia, United States
Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Cartersville, Georgia, United States
Northwest Georgia Oncology Centers, a Service of WellStar Cobb Hospital, Douglasville, Georgia, United States
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital, Marietta, Georgia, United States
Comprehensive Urologic Care, SC, Lake Barrington, Illinois, United States
Mid-Illinois Hematology & Oncology Associates, Ltd, Normal, Illinois, United States
Willis Knighton Advanced Urology, Shreveport, Louisiana, United States
Henry Ford Health System, Detroit, Michigan, United States
Revive Research Institute, Inc., Farmington Hills, Michigan, United States
David C. Pratt Cancer Center, Saint Louis, Missouri, United States
New Jersey Cancer Care, P.A., Belleville, New Jersey, United States
Premier Medical Group of the Hudson Valley PC, Poughkeepsie, New York, United States
Providence Cancer Institute Clackamas Clinic, Clackamas, Oregon, United States
Providence Cancer Institute Newberg Clinic, Newberg, Oregon, United States
Providence Cancer Institute Willamette Falls, Oregon City, Oregon, United States
Providence Cancer Institute Franz Clinic, Portland, Oregon, United States
Providence Portland Medical Center, Portland, Oregon, United States
Providence Oncology and Hematology Care Clinic - Westside, Portland, Oregon, United States
Keystone Urology Specialists, Lancaster, Pennsylvania, United States
Carolina Urologic Research Center, Myrtle Beach, South Carolina, United States
Parkway Surgery Center, Myrtle Beach, South Carolina, United States
Bristol Regional Medical Center, Bristol, Tennessee, United States
Ballad Health Cancer Care - Kingsport, Kingsport, Tennessee, United States
Holston Valley Hospital and Medical Center, Kingsport, Tennessee, United States
Indian Path Community Hospital, Kingsport, Tennessee, United States
Kelsey Research Foundation, Houston, Texas, United States
Oncology Consultants, P.A., Houston, Texas, United States
oncology Consultants, P.A., Houston, Texas, United States
Kelsey-Seybold Clinic, Houston, Texas, United States
Houston Metro Urology, Houston, Texas, United States
Oncology Consultants P.A., Houston, Texas, United States
Urology San Antonio, PA dba USA Clinical Trials, San Antonio, Texas, United States
Urology San Antonio, San Antonio, Texas, United States
Baptist M&S Imaging (STONE OAK), San Antonio, Texas, United States
Texas Oncology-Deke Slayton Cancer Center, Webster, Texas, United States
Huntsman Cancer Institute - University of Utah, Salt Lake City, Utah, United States
COIBA, Berazategui, Buenos Aires, Argentina
Centro de Investigacion Pergamino SA - Clinica Pergamino SA, Pergamino, Buenos Aires, Argentina
Centro de Investigaciones Clínicas - Clínica Viedma, Viedma, RÍO Negro, Argentina
Centro Medico San Roque, San Miguel de Tucuman, Tucuman, Argentina
Centro Oncologico Korben, Caba, , Argentina
Instituto Médico Especializado Alexander Fleming, Caba, , Argentina
Centro Medico Privado CEMAIC, Córdoba, , Argentina
Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia
Southern Medical Day Care Centre, Wollongong, New South Wales, Australia
Gallipoli Medical Research Foundation, Greenslopes Private Hospital, Brisbane, Queensland, Australia
Gold Coast University Hospital, Southport, Queensland, Australia
The Queen Elizabeth Hospital, Woodville South, South Australia, Australia
Epworth Freemasons-Epworth HealthCare, East Melbourne, Victoria, Australia
Cabrini Hospital, Malvern, Victoria, Australia
Western Health, Sunshine Hospital, St Albans, Victoria, Australia
Onze Lieve Vrouw Ziekenhuis Aalst, Aalst, , Belgium
Institut Jules Bordet, Anderlecht, , Belgium
Cliniques universitaires Saint-Luc, Brussels, , Belgium
AZ (Algemeen Ziekenhuis) Maria Middelares, Gent, , Belgium
AZ (Algemeen Ziekenhuis) Sint-Lucas, Gent, , Belgium
AZ (Algemeen Ziekenhuis) Groeninge, Kortrijk, , Belgium
CHU de Liege, Liege, , Belgium
ZNA Jan Palfijn, Merksem, , Belgium
Multiprofile Hospital for Active Treatment - Uni Hospital OOD, Panagyurishte, , Bulgaria
Complex Oncology Center - Plovdiv EOOD, Plovdiv, , Bulgaria
Independent medical-diagnostic laboratory "Medisken" EOOD, Plovdiv, , Bulgaria
University Multiprofile Hospital for Active Treatment Sveti Georgi EAD, Plovdiv, , Bulgaria
Complex Oncology Center - Shumen EOOD, Shumen, , Bulgaria
Acibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda EAD, Sofia, , Bulgaria
Acibadem City Clinic University Multiprofile Hospital for Active Treatment EOOD, Sofia, , Bulgaria
Complex Oncology Center - Stara Zagora Ltd., Stara Zagora, , Bulgaria
MRI SMDLOD "Mediscan" Ltd, Stara Zagora, , Bulgaria
UMHAT "Prof. Dr. Stoyan Kirkovich", Stara Zagora, , Bulgaria
Prostate Cancer Centre, Calgary, Alberta, Canada
Centre of Applied Urology Research, Nova Scotia Health Authority, Halifax, Nova Scotia, Canada
London Health Sciences Centre, London, Ontario, Canada
The Ottawa Hospital Cancer Center, Ottawa, Ontario, Canada
University Health Network-Princess Margaret Cancer Centre, Toronto, Ontario, Canada
CIUSSS- saguenay-Lac-Saint-Jean, Chicoutimi, Quebec, Canada
Urology South Shore Research, Greenfield Park, Quebec, Canada
CHUM - Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada
Jewish General Hospital, Montreal, Quebec, Canada
McGill University Health Center, Montreal, Quebec, Canada
The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China
Peking University First Hospital, Beijing, Beijing, China
Lanzhou University Second Hospital, Lanzhou, Gansu, China
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China
Nanfang Hospital of Southern Medical University, Guangzhou, Guangdong, China
Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, China
Henan Cancer Hospital, Zhengzhou, Henan, China
Union Hospital, Tongji Medical College of Huazhong University of Science & Technology, Wuhan, Hubei, China
Tongji Hospital, Tongji Medical College,Huazhong University of Science and Technology, Wuhan, Hubei, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
The Third Xiangya Hospital of Central South University, Changsha, Hunan, China
Zhongda Hospital Southeast University, Nanjing, Jiangsu, China
Nantong Tumor Hospital, Nantong, Jiangsu, China
The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China
Jiangxi Provincial Cancer Hospital, Nanchang, Jiangxi, China
The First hospital of Jilin University, Changchun, Jilin, China
The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
Fudan University Cancer Hospital, Shanghai, Shanghai, China
West China Hospital of Sichuan University, Chengdu, Sichuan, China
The Second Hospital of Tianjin Medical University, Tianjin, Tianjin, China
Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China
Ningbo First Hospital, Ningbo, Zhejiang, China
The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
The First Affiliated Hospital Chongqing Medical University, Chongqing, , China
Fakultni nemocnice Olomouc, Olomouc, , Czechia
Fakultni nemocnice Ostrava, Ostrava - Poruba, , Czechia
Fakultni nemocnice Kralovske Vinohrady, Praha 10, , Czechia
Fakultni nemocnice v Motole, Praha 5, , Czechia
Fakultni nemocnice Bulovka, Praha 8- Liben, , Czechia
Helsinki University Hospital, Helsinki, , Finland
Docrates Cancer Center, Helsinki, , Finland
Kuopio University Hospital, Kuopio, , Finland
Tampere University Hospital, Tampere, , Finland
Turku University Hospital, Turku, , Finland
CHU Morvan de Brest, Brest, Bretagne, France
Hopital Henri Mondor, Creteil, ILE DE France, France
Centre Hospitalier Universitaire d'Angers, Angers Cedex 9, , France
Clinique Belharra, Bayonne, , France
CHU Morvan de Brest, Brest, , France
Centre de Cancerologie de la Sarthe, Le Mans, , France
Clinique Victor Hugo, Le Mans, , France
Hopital Prive le Bois, Lille, , France
Centre Leon Berard, LYON Cedex 08, , France
Hopital Bichat - Claude Bernard, Paris cedex 18, , France
Hopital Bichat - Claude Bernard, Paris, , France
Hopital Lyon Sud, Pierre-Benite, , France
Clinique La Croix du Sud - Ramsay Sante, Quint Fonsegrives, , France
Institut Jean Godinot, Reims Cedex, , France
CHP Saint-Grégoire, Saint Gregoire, , France
Hopitaux Universitaires de Strasbourg - ICANS (Institut de Cancerologie Strasbourg Europe), Strasbourg, , France
Institut de cancerologie de Lorraine, Vandoeuvre-Les-Nancy, , France
Gustave Roussy, Villejuif Cedex, , France
Universitaetsmedizin Goettingen, Göttingen, Niedersachsen, Germany
Urologische Gemeinschaftspraxis Wesel, Wesel, Nordrhein-westfalen, Germany
Universitätsklinikum Jena, Jena, Thüringen, Germany
Charite Universitaetsmedizin Berlin - Campus Mitte, Berlin, , Germany
Urologicum Duisburg, Duisburg, , Germany
Universitaetsklinikum Frankfurt, Frankfurt, , Germany
Institut fuer Diagnostische und Interventionelle Radiologie, Goettingen, , Germany
Klinik fuer Nuklearmedizin, Goettingen, , Germany
Universitaetsklinik Heidelberg, Heidelberg, , Germany
Jena University Hospital, Jena, , Germany
Uro-/Onkologisches Zentrum, Leipzig, , Germany
Studienpraxis Urologie, Nuertingen, , Germany
Universitaetsklinikum Tuebingen, Tuebingen, , Germany
Péterfy Kórház-Rendelőintézet és Manninger Jenő Országos Traumatológiai Intézet, Budapest, , Hungary
Országos Onkológiai Intézet, Budapest, , Hungary
Uzsoki Utcai Korhaz, Budapest, , Hungary
Jahn Ferenc Del-pesti Korhaz es Rendelointezet, Budapest, , Hungary
Indraprastha Apollo Hospital, New Delhi, Delhi, India
Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, Delhi, India
Gujarat Hospital - Gastro and Vascular Centre, Surat, Gujarat, India
Artemis hospital, Gurugram, Haryana, India
Medanta- The Medicity hospital, Gurugram, Haryana, India
Bhakti Vedanta Hospital and Research Institute, Mumbai, Thane, Maharashtra, India
Bhaktivedanta Hospital and Research Institute, Mumbai, Thane, Maharashtra, India
TATA Memorial Hospital, Mumbai, Maharashtra, India
Sahyadri Clinical Research & Development Centre, Pune, Maharashtra, India
Sahyadri Super Speciality Hospital, Pune, Maharashtra, India
Valentis Cancer Hospital, Meerut, Uttar Pradesh, India
Netaji Subhas Chandra Bose Cancer Hospital, Kolkata, WEST Bengal, India
Azienda Ospedaliero-Universitaria Policlinico S. Orsola Malpighi, Bologna, BO, Italy
ASST Cremona, Cremona, CR, Italy
Istituto Romagnolo per lo Studio dei Tum.ori "Dino Amadori" (IRST), Meldola, FC, Italy
Fondazione Casa Sollievo della Sofferenza, San Giovanni Rotondo, FG, Italy
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale - Napoli, Napoli, Naples, Italy
Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, PN, Italy
Ospedale Santa Chiara, Trento, TN, Italy
AOU San Luigi Gonzaga, Orbassano, TO, Italy
Ospedale San Donato, Arezzo, , Italy
IRCCS Istituto Tumori "Giovanni Paolo II" di Bari, Bari, , Italy
ASST Papa Giovanni XXIII, Bergamo, , Italy
ASST degli Spedali Civili de Brescia, Brescia, , Italy
Azienda Ospedaliera Universitaria Integrata Verona, Verona, , Italy
Nagoya University Hospital, Nagoya, Aichi, Japan
Hirosaki University School of Medicine & Hospital, Hirosaki, Aomori, Japan
Chiba Cancer Center, Chiba City, Chiba, Japan
Chiba cancer center, Chiba-shi, Chiba, Japan
National Cancer Center Hospital East, Kashiwa, Chiba, Japan
National Hospital Organization Shikoku Cancer Center, Matsuyama, Ehime, Japan
National Hospital Organization Kyushu Cancer Center, Fukuoka-shi, Fukuoka, Japan
National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Hiroshima, Japan
National Hospital Organization Hokkaido Cancer Center, Sapporo, Hokkaido, Japan
Hokkaido University Hospital, Sapporo, Hokkaido, Japan
Kanazawa University Hospital, Kanazawa, Ishikawa, Japan
Yokohama City University Medical Center, Yokohama, Kanagawa, Japan
Yokosukakyosai, Yokosuka, Kanagawa, Japan
Osaka International Cancer Institute, Osaka-shi, Osaka, Japan
Kindai University Hospital, Osakasayama, Osaka, Japan
Osaka University Hospital, Suita, Osaka, Japan
Hamamatsu University Hospital, Hamamatsu, Shizuoka, Japan
National Hospital Organization Tokyo Medical Center, Meguro-Ku, Tokyo, Japan
Keio University Hospital, Shinjuku-ku, Tokyo, Japan
Kagoshima University Hospital, Kagoshima, , Japan
National Hospital Organization Kumamoto Medical Center, Kumamoto, , Japan
Tokushima University Hospital, Tokushima, , Japan
Yamagata University Hospital, Yamagata, , Japan
National Cancer Center, Goyang-si, Gyeonggi-do, Korea, Republic of
Chonnam National University Hwasun Hospital, Hwasun-gun, Jeollanam-do, Korea, Republic of
Seoul National University Bundang Hospital, Seongnam, Kyǒnggi-do, Korea, Republic of
Samsung Medical Center, Seoul, Seoul-teukbyeolsi, Korea, Republic of
Kyungpook National University Chilgok Hospital, Daegu, , Korea, Republic of
Seoul National University Hospital, Seoul, , Korea, Republic of
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Asan Medical Center, Seoul, , Korea, Republic of
Gangnam Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, , Korea, Republic of
Ewha Womans University Mokdong Hospital, Seoul, , Korea, Republic of
Oncologia Integral Satelite SA de CV, Naucalpan de Juarez, Estado DE Mexico, Mexico
Preparaciones Oncológicas S.C., Leon, Guanajuato, Mexico
Axis Heilsa S. de R.L. de C.V., Monterrey, Nuevo LEÓN, Mexico
Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Nuevo LEÓN, Mexico
Oaxaca Site Management Organization, Oaxaca de Juarez, Oaxaca, Mexico
Centro de Investigacion Clinica de Oaxaca, Oaxaca, , Mexico
Instituto Veracruzano en Investigación Clínica S.C., Veracruz, , Mexico
Meander Medisch Centrum, Amersfoort, Utrecht, Netherlands
Stichting HagaZiekenhuis, Den Haag, , Netherlands
Sykehuset Innlandet Gjoevik, Gjoevik, , Norway
MRRC n.a. A.F. Tsyb - branch of FSBI "NMRC of Radiology" Minzdrav Russia, Obninsk, Kaluga Region, Russian Federation
Private Medical Institution "Euromedservice", Pushkin, Saint-petersburg, Russian Federation
Limited Liability Company "4D Ultrasound Clinic" (LLC "4D Ultrasound Clinic"), Pyatigorsk, Stavropol Region, Russian Federation
Evimed Llc, Chelyabinsk, , Russian Federation
SBIH "Chelyabinsk Regional Clinical Centre of Oncology and Nuclear Medicine", Chelyabinsk, , Russian Federation
Regional Budgetary Healthcare Institution "Ivanovskiy Regional Oncology Dispensary" (RBHI "IvROD"), Ivanovo, , Russian Federation
Federal State Budgetary Institution "Russian Research Center of Roentgenology and Radiology" of t, Moscow, , Russian Federation
Branch of the Limited Liability Company "Hadassah Medical Ltd.", Moscow, , Russian Federation
Federal State Budgetary Institution "Central Clinical Hospital with ambulance", Moscow, , Russian Federation
BHI of Omsk region "Clinical Oncological Dispensary", Omsk, , Russian Federation
LLC "Medicina Severnoy Stolitsy", Saint-Petersburg, , Russian Federation
LLC "Severo-Zapadny Medical Center", Saint-Petersburg, , Russian Federation
Private Institution Educational Organization of Higher Education "Medical University "REAVIZ", Samara, , Russian Federation
SAHI Republican Clinical Oncology Dispensary under the Ministry of Health, Republic of Bashkortostan, Ufa, , Russian Federation
Budgetary Healthcare Institution of Vologda region "Vologda Regional Clinical Hospital", Vologda, , Russian Federation
Budgetary Healthcare Institution of Vologda region "Vologda Regional Clinical Hospital", Vologda, , Russian Federation
State Budgetary Institution of Healthcare of Yaroslavl Region "Regional Clinical Oncology Hospital", Yaroslavl, , Russian Federation
Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica, Banska Bystrica, , Slovakia
Narodny onkologicky ustav, Bratislava, , Slovakia
Vychodoslovensky onkologicky ustav, a.s., Kosice, , Slovakia
UROEXAM, spol. s r.o., Nitra, , Slovakia
POKO Poprad s.r.o., Poprad, , Slovakia
MILAB s.r.o., Presov, , Slovakia
Privatna urologicka ambulancia, s.r.o., Trencin, , Slovakia
15 Eton Road, Johannesburg, Gauteng, South Africa
Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, Gauteng, South Africa
WCR Office, Johannesburg, Gauteng, South Africa
Sandton Oncology Medical Group (Pty) Ltd, Johannesburg, Gauteng, South Africa
Wits Clinical Research, Parktown, Johannesburg, Gauteng, South Africa
Clinical Research Unit, University of Pretoria, Pretoria, Gauteng, South Africa
Hospital General Universitario de Elche, Elche, Alicante, Spain
Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
Hospital Germans Trias i Pujol, Badalona, Barcelona [barcelona], Spain
Althaia, Xarxa Assistencial Universitària de Manresa, Manresa, Barcelona, Spain
Hospital Universitario Lucus Augusti, Lugo, Galicia, Spain
Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, Comunidad DE, Spain
Complejo Hospitalario de Navarra, Pamplona, Navarra, Spain
Hospital Universitari Sant Joan de Reus, Reus, Tarragona, Spain
Fundación Instituto Valenciano de Oncología, Valencia, Valenciana, Comunitat, Spain
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Hospital Clínic de Barcelona, Barcelona, , Spain
Hospital Universitario Reina Sofía, Cordoba, , Spain
Hospital Universitario Gregorio Marañón, Madrid, , Spain
MD Anderson Cancer Center, Madrid, , Spain
Hospital Clinico San Carlos, Madrid, , Spain
Hospital Universitario Virgen de la Macarena, Sevilla, , Spain
Hospital Politecnic Universitari La Fe, Valencia, , Spain
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, , Taiwan
Taichung Veterans General Hospital, Taichung, , Taiwan
National Cheng Kung University Hospital, Tainan, , Taiwan
National Taiwan University Hospital, Taipei, , Taiwan
Taipei Veterans General Hospital, Taipei, , Taiwan
Linkou Chang Gung Memorial Hospital, Taoyuan City, , Taiwan
Ankara Bilkent Sehir Hastanesi, Bilkent, Ankara, Turkey
Adana City Training and Research Hospital, Adana, , Turkey
Ankara University Faculty of Medicine, Ankara, , Turkey
Ankara City Hospital, Ankara, , Turkey
Trakya University Medical Faculty, Edirne, , Turkey
Istanbul University, Cerrahpasa Faculty of Medicine, Istanbul, , Turkey
Goztepe Prof. Dr. Suleyman Yalcin City Hospital, Istanbul, , Turkey
Inonu University, Faculty of Medicine, Malatya, , Turkey
MI Kryvyi Rih Oncology Dispensary of Dnipropetrovsk Regional Council; Chemotherapy Department, Kryviy Rih, Dnipropetrovska Oblast, Ukraine
Medical & diagnostic center of LISOD-Israeli Oncological Hosp "MedX-ray International Group", Pliuty Village, KYIV Region, Ukraine
Asklepion Medical Center, Khodosivka, Kyivska Oblast, Ukraine
National Cancer Institute, Kyiv, Kyivska Oblast, Ukraine
Municipal Ent "Dnipropetrovsk Regional Clinical Hosp (I.I.Mechnikov Dnipropetrovsk Regional council), Dnipro, , Ukraine
Municipal Non-profit Enterprise "City Clinical Hospital #4" of Dnipro City Council, Dnipro, , Ukraine
Communal non-profit enterprise "Regional clinical hospital of Ivano-Frankivsk Regional Council", Ivano-Frankivsk, , Ukraine
Municipal Non-Commercial Enterprise of Kharkiv Regional Council Regional Medical Clinical Center of, Kharkiv, , Ukraine
Communal Non-Profit Enterprise "Regional Center of Oncology", Kharkiv, , Ukraine
Comm Noncommerc Entp Lviv Reg Council "Lviv Oncological Regional Therapeutical and Diagnostic Cntre, Lviv, , Ukraine
Royal Devon and Exeter NHS Foundation Trust, Exeter, Devon, United Kingdom
Maidstone and Tunbridge Wells NHS Trust, Maidstone, Kent, United Kingdom
Lancashire Teaching Hospitals NHS Foundation Trust, Preston, Lancashire, United Kingdom
NHS Lothian, Edinburgh, Midlothian, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, South Yorkshire, United Kingdom
University Hospitals Birmingham NHS Foundation Trust, Birmingham, , United Kingdom
NHS Greater Glasgow and Clyde, Glasgow, , United Kingdom
The Royal Marsden NHS Foundation Trust, London, , United Kingdom
Imperial College Healthcare NHS Trust, London, , United Kingdom
The Christie NHS Foundation Trust, Manchester, , United Kingdom
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