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Spots Global Cancer Trial Database for Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

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Trial Identification

Brief Title: Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

Official Title: A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer

Study ID: NCT04221542

Conditions

Prostate Cancer

Study Description

Brief Summary: Evaluate the safety and tolerability of AMG 509 in adult participants and determine the maximum tolerated dose (MTD) or recommended phase 2 dose (RP2D).

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: MALE

Healthy Volunteers: No

Locations

City of Hope National Medical Center, Duarte, California, United States

Providence Saint Jude Medical Center, Fullerton, California, United States

University of California San Francisco, San Francisco, California, United States

Yale Cancer Center, New Haven, Connecticut, United States

Emory University, Atlanta, Georgia, United States

Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States

Alliance for Multispecialty Research, Merriam, Kansas, United States

Tulane Medical Center, New Orleans, Louisiana, United States

Washington University, Saint Louis, Missouri, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Duke University Medical Center, Durham, North Carolina, United States

Oncology Hematology Care Incorporated, Cincinnati, Ohio, United States

Thomas Jefferson University, Philadelphia, Pennsylvania, United States

University of Pittsburgh Medical Center Cancer Pavillion, Pittsburgh, Pennsylvania, United States

Prisma Health Upstate, Greenville, South Carolina, United States

Sanford Health, Sioux Falls, South Dakota, United States

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Virginia Cancer Specialists PC, Fairfax, Virginia, United States

Virginia Oncology Associates, Norfolk, Virginia, United States

Fred Hutchinson Cancer Center, Seattle, Washington, United States

Chris OBrien Lifehouse, Camperdown, New South Wales, Australia

Monash Medical Centre, Clayton, Victoria, Australia

Sun Yat-sen University, Cancer Center, Guangzhou, Guangdong, China

Fudan University Shanghai Cancer Centre, Shanghai, Shanghai, China

Zhejiang Provincial Peoples Hospital, Hangzhou, Zhejiang, China

Universitaetsklinikum Essen, Essen, , Germany

Universitaetsklinikum Heidelberg, Heidelberg, , Germany

Klinikum rechts der Isar der TUM, Muenchen, , Germany

Universitaetsklinikum Muenster, Muenster, , Germany

National Cancer Center Hospital East, Kashiwa-shi, Chiba, Japan

Yokohama City University Hospital, Yokohama-shi, Kanagawa, Japan

The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Koto-ku, Tokyo, Japan

Seoul National University Hospital, Seoul, , Korea, Republic of

Asan Medical Center, Seoul, , Korea, Republic of

Hospital da Luz, SA, Lisboa, , Portugal

Instituto Portugues de Oncologia do Porto Francisco Gentil, EPE, Porto, , Portugal

Hospital Universitari Vall d Hebron, Barcelona, Cataluña, Spain

Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña, Spain

Clinica Universidad de Navarra, Pamplona, Navarra, Spain

Hospital Clinico San Carlos, Madrid, , Spain

Hospital Universitario 12 de Octubre, Madrid, , Spain

Istituto Oncologico della Svizzera Italiana, Bellinzona, , Switzerland

Kantonsspital Graubuenden, Chur, , Switzerland

Centre Hospitalier Universitaire Vaudois, Lausanne, , Switzerland

Kantonsspital Sankt Gallen, Sankt Gallen, , Switzerland

National Taiwan University Hospital, Taipei, , Taiwan

Linkou Chang Gung Memorial Hospital of Chang Gung Medical Foundation, Taoyuan, , Taiwan

Contact Details

Name: MD

Affiliation: Amgen

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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