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Brief Title: High Impact Training to Patients With Prostate Cancer and Bone Metastases
Official Title: High Impact Training to Patients With Prostate Cancer and Bone Metastases
Study ID: NCT06259279
Brief Summary: HIP is a randomized controlled trial. The aim is investigate the effect, safety and feasibility of brief, high-impact exercise targeting bones in patients with prostate cancer and bone metastases. Furthermore, to investigate the effects of the intervention on bone status (bone mineral density) and body composition, physical function and performance, patient reported quality-of-life outcomes, falls and hospitalizations.
Detailed Description: Participants assigned to the intervention group will participate in a 32-week, twice-weekly, 30-minute, supervised HIP program at the hospital in Herlev, Denmark. To ensure a safe transition to high-intensity exercise, the first eight weeks of the intervention includes self-bodyweight and low-impact variations with a focus on getting used to use weight training equipment and gradually learning the movement patterns of the HIP exercises. All participants should be able to perform the four basic exercises of the intervention within two months. The resistance exercises (deadlift, overhead press, and squats) will be performed in five sets of five repetitions for the remaining intervention period, maintaining an intensity of \> 80% to 85% of 1 repetition maximum (RM).
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Herlev and Gentofte Hospital, Herlev, , Denmark
Name: Anne-Mette Ragle, PhD student
Affiliation: Copenhagen University Hospital at Herlev
Role: PRINCIPAL_INVESTIGATOR
Name: Peter B Østergren
Affiliation: Peter Østergren
Role: STUDY_DIRECTOR