Spots Global Cancer Trial Database for bone metastases
Every month we try and update this database with for bone metastases cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Hypofractionated Radiotherapy (16/2) for the Palliation of Complicated Bone Metastases in Patients With KPS | NCT02376322 | Bone Metastases | Radiotherapy | 18 Years - | Santa Casa de Porto Alegre | |
| Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Men With Previously Untreated Germ Cell Cancer | NCT00003941 | Mediastinal Can... Metastatic Canc... Testicular Germ... | bleomycin sulfa... filgrastim cisplatin etoposide ifosfamide bone marrow abl... peripheral bloo... | 16 Years - 50 Years | European Organisation for Research and Treatment of Cancer - EORTC | |
| Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases | NCT00079001 | Metastatic Canc... Prostate Cancer | zoledronic acid placebo androgen depriv... GnRH agonist Calcium supplem... Vitamin D | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Trastuzumab Plus R115777 in Treating Patients With Advanced or Metastatic Cancer | NCT00005842 | Cancer | trastuzumab tipifarnib | 18 Years - | National Cancer Institute (NCI) | |
| BAY88-8223, Does Response Study in HRPC Patients | NCT00667199 | Hormone Refract... Bone Metastases | Radium-223 dich... | 40 Years - | Bayer | |
| Study of AMG 162 in Subjects With Advanced Cancer Currently Being Treated With Intravenous (IV) Bisphosphonates | NCT00104650 | Bone Metastases... Bone Metastases... Bone Metastases... | AMG 162 180 mg ... IV Bisphosphona... AMG 162- 180 mg... | 18 Years - | Amgen | |
| The Combination Therapy With Ra-223 and Enzalutamide | NCT03305224 | Castration-resi... Bone Metastases | Ra-223 in combi... | 20 Years - | Osaka City University | |
| QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas | NCT01231347 | Adenocarcinoma ... Advanced Solid ... Cancer Cancer of Pancr... Cancer of the P... Metastases Metastatic Canc... Metastatic Panc... Pancreas Cancer Pancreatic Canc... Bone Metastases Endocrine Cance... Oncology Oncology Patien... Solid Tumors Advanced Malign... | AMG 479 Placebo AMG 479 gemcitabine | 18 Years - | NantCell, Inc. | |
| Radiosurgical Hypophysectomy for Bone Metasteses Pain | NCT03377517 | Bone Metastases | radiosurgical h... | 18 Years - 100 Years | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
| S0308 Zoledronate or Ibandronate in Preventing Bone Problems in Women With Stage IV Breast Cancer That Has Spread to the Bone | NCT00301886 | Breast Cancer Hypercalcemia o... Metastatic Canc... Pain | ibandronate zoledronate quality-of-life... | 18 Years - | SWOG Cancer Research Network | |
| Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement | NCT00869206 | Breast Adenocar... DS Stage I Plas... DS Stage II Pla... Metastatic Mali... Pain Musculoskeletal... Urinary Complic... | zoledronic acid | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients | NCT03336983 | Prostate Cancer Bone Metastases | Zoledronic Acid Enzalutamide | 18 Years - | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | |
| EPIBONE Study: a Prospective Study on Feasibility, Safety and Accuracy | NCT06376682 | Bone Metastases Fractures, Bone Bone Tumor | CT-guided bone ... | 18 Years - | Quantum Surgical | |
| Hypofractionated Radiotherapy (16/2) for the Palliation of Complicated Bone Metastases in Patients With KPS | NCT02376322 | Bone Metastases | Radiotherapy | 18 Years - | Santa Casa de Porto Alegre | |
| Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis | NCT00762346 | Non Small Cell ... Bone Metastases High NTX Level | zometa | 18 Years - | Sun Yat-sen University | |
| Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases | NCT00242554 | Prostate Cancer | Zoledronic acid | 18 Years - 80 Years | Novartis | |
| Atrasentan and Zometa for Men With Prostate Cancer Metastatic to Bone | NCT00181558 | Prostate Cancer Adenocarcinoma ... | Atrasentan Zoledronic Acid... | 18 Years - | Massachusetts General Hospital | |
| Safety and Efficacy of Cryoablation Combined With Radiation Therapy for the Palliation of Painful Bone Metastases | NCT01461252 | Pain Neoplasm Metast... | Cryoablation Radiation | 18 Years - | Boston Scientific Corporation | |
| 3 Tesla Magnetic Resonance Guided High Intensity Focused Ultrasound in the Treatment of Pain From Bone Metastases of Solid Tumors | NCT02718404 | Solid Tumors | MR-HIFU Treatme... MR contrast med... MR images | 18 Years - | Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori | |
| Metastatic Pathologic Fractures, Short Term Results | NCT05825456 | Pathologic Frac... Bone Metastases Metastatic Canc... | endoprosthetic ... Intramedullary ... Open reduction ... | - | Ankara University | |
| Radioiodine-avid Bone Metastases From Thyroid Cancer Without Structural Abnormality | NCT04141306 | Bone Metastases Thyroid Cancer | Administrative ... Clinical data Histological da... Imaging data Biological data Further treatme... | 18 Years - 80 Years | Hospices Civils de Lyon | |
| Bipolar RFA of Painful Extra-spinal Bone Metastases | NCT03738670 | Multi-metastati... | Percutaneous RF... | 18 Years - | University Hospital, Strasbourg, France | |
| Ablation and Cementoplasty for Painful Bone Lesions | NCT04635137 | Bone Lesion Bone Metastases Spine Metastase... | Ablation and Ce... | 18 Years - | University of Calgary | |
| Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone Metastases | NCT00081159 | Metastatic Canc... Prostate Cancer | Doxorubicin hyd... Goserelin aceta... Leuprolide acet... Zoledronic acid orchiectomy strontium chlor... | - | M.D. Anderson Cancer Center | |
| Radium-223 Dichloride (BAY88-8223) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases | NCT01516762 | Prostatic Neopl... | Radium-223 dich... | 18 Years - | Bayer | |
| Study Comparing the Safety and Effectiveness of Magnetic Resonance Guided Focused Ultrasound (MRgFUS) and External Beam Radiation (EBRT) for Treatment of Metastatic Bone Tumors and Multiple Myeloma | NCT01091883 | Bone Cancer Bone Metastases Pain | Exablate treatm... Radiation | 18 Years - | InSightec | |
| Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement | NCT00869206 | Breast Adenocar... DS Stage I Plas... DS Stage II Pla... Metastatic Mali... Pain Musculoskeletal... Urinary Complic... | zoledronic acid | 18 Years - | Alliance for Clinical Trials in Oncology | |
| A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC) | NCT00172042 | Non-Small-Cell ... | Zoledronic acid... | 18 Years - | Novartis | |
| Association of Bone and Metabolic Parameters With Overall Survival in Patients With Bone Metastases From Adenocarcinoma Lung Cancer (POUMOS) | NCT02810262 | Bone Metastases Lung Cancer | Bone metastases... | 18 Years - | Hospices Civils de Lyon | |
| clinIcal Efficacy and Safety of Incadronate in Breast Cancer With Bone Metastases | NCT06392217 | Breast Cancer Bone Metastases | 18 Years - | Fudan University | ||
| To Evaluate the Efficacy and Safety of QL1206 and Xgeva in Patients With Bone Metastases From Solid Tumors | NCT04550949 | Bone Metastases | QL1206 Xgeva | 18 Years - 80 Years | Qilu Pharmaceutical Co., Ltd. | |
| Rapid Radiation Therapy for Painful Osseous Metastatic Disease | NCT01391234 | Bone Metastases | STAT RT plannin... | 18 Years - | University of Virginia | |
| Radium-223 Dichloride (BAY88-8223) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases | NCT01516762 | Prostatic Neopl... | Radium-223 dich... | 18 Years - | Bayer | |
| Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence (ZTE, Pseudo-CT) for the Detection of Bone Lesions in Multiple Myeloma: Comparison With Pet / CT and Whole Body Scanner | NCT05381077 | Multiple Myelom... Bone Metastases | MRI | 18 Years - 99 Years | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | |
| Zoledronate in Preventing Skeletal (Bone)-Related Events in Men Who Are Receiving Androgen Deprivation Therapy For Prostate Cancer and Bone Metastases | NCT00079001 | Metastatic Canc... Prostate Cancer | zoledronic acid placebo androgen depriv... GnRH agonist Calcium supplem... Vitamin D | 18 Years - | Alliance for Clinical Trials in Oncology | |
| Imaging of Prostate and Breast Cancer Bone Metastases Using Magnetic Resonance Imaging and Nuclear Medicine Techniques | NCT01339780 | Bone Metastases | BS, SPECT/CT, P... | 40 Years - 80 Years | Turku University Hospital | |
| A Study of Alpharadin With Docetaxel in Patients With Bone Metastasis From Castration-Resistant Prostate Cancer (CRPC) | NCT01106352 | Bone Metastases Castration-Resi... | Radium-223 dich... Docetaxel | 18 Years - | Bayer | |
| Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain | NCT00550654 | Kidney Cancer Melanoma (Skin) Metastatic Canc... Ovarian Cancer Sarcoma Unspecified Adu... | questionnaire a... 3-dimensional c... hypofractionate... image-guided ra... tomotherapy | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| F-18 PET Bone Scans Versus Tc-99m Bone Scans for the Diagnosis of Bone Metastases | NCT01254929 | Cancer Bone Metastases | F-18 PET bone s... Tc-99m bone sca... | 18 Years - | Seattle Nuclear Medicine | |
| Open Label Extension In Cancer Patients | NCT00830180 | Neoplasms Bone Metastases | Anti-NGF AB | 18 Years - | Pfizer | |
| Comparing Immobilisation Shells in Cranial Radiotherapy | NCT02599142 | Brain Metastase... Bone Metastases Brain Tumor, Pr... Brain Tumor Adu... Brain Tumor - M... | Group A: Closed... Group B: Open-f... | 18 Years - | Royal Marsden NHS Foundation Trust | |
| Exercise Prescription in Patients With Bone Metastases | NCT03979118 | Advanced Cancer Bone Metastases | 18 Years - | University of Dublin, Trinity College | ||
| Ibandronate or Zoledronate in Treating Patients With Newly Diagnosed Bone Metastases From Breast Cancer | NCT00326820 | Breast Cancer Hypercalcemia o... Metastatic Canc... | ibandronate sod... zoledronic acid Zolendronic Aci... | 18 Years - | Wales Cancer Trials Unit | |
| Lapatinib in Treating Patients With Advanced or Metastatic Breast Cancer That Overexpresses HER2 | NCT00544804 | Breast Cancer Metastatic Canc... | lapatinib ditos... gene expression... diagnostic labo... | 18 Years - | University of California, San Francisco | |
| Open-label Phase IV Clinical Trial to Evaluate the Safety and Tolerability of Zoledronic Acid in Patients With Prostate Cancer and Bone Metastases | NCT00242554 | Prostate Cancer | Zoledronic acid | 18 Years - 80 Years | Novartis | |
| Aspirin and Compression Devices for VTE Prophylaxis in Orthopaedic Oncology | NCT01696760 | Bone Metastases Musculoskeletal... Soft Tissue Sar... Thromboembolism | acetylsalicylic... enoxaparin PCD | 18 Years - | Ohio State University Comprehensive Cancer Center | |
| Monoclonal Antibody Compared With Zoledronate in Treating Women With Breast Cancer and Bone Metastases | NCT00060138 | Breast Cancer Hypercalcemia o... Metastatic Canc... Pain | monoclonal anti... zoledronic acid | 18 Years - | Chugai Pharmaceutical | |
| MR Guided Focused Ultrasound Surgery in the Treatment of Pain From Bone Tumors w/ the ExAblate 2000 Strappable System | NCT03547557 | Bone Metastases | Exablate 2000 s... | 18 Years - | InSightec | |
| Open Label Extension to SRE Studies in United Kingdom and Czech Republic Only | NCT00950911 | Bone Metastases... Bone Metastases... Bone Metastases... | amg 162 | 18 Years - | Amgen | |
| Tandutinib in Treating Patients With Progressive Prostate Cancer and Bone Metastases | NCT00390468 | Metastatic Canc... Pain Prostate Cancer | Tandutinib | 18 Years - | National Cancer Institute (NCI) | |
| Helical Tomotherapy as a Radiotherapy Technique for Treating Bone Metastases | NCT00168129 | Bone Neoplasms | Helical tomothe... | 18 Years - | AHS Cancer Control Alberta | |
| Prospective PRO/QoL Registry for Patients With Bone Metastases of Breast or Prostate Cancer | NCT02410044 | Breast Cancer Prostate Cancer Bone Metastases | 18 Years - | iOMEDICO AG | ||
| Concurrent Xeloda and Radiotherapy for Bone Metastases | NCT00192777 | Solid Tumors Bone Metastases | Xeloda External Beam R... | 18 Years - | Rambam Health Care Campus | |
| Risk Factors for Skeletal Related Events in Breast Cancer Patients Receiving Bisphosphonates for Bone Metastases | NCT01144481 | Bone Metastases Breast Cancer | - | University Health Network, Toronto | ||
| ExAblate Conformal Bone System Treatment of Metastatic Bone Tumors for the Palliation of Pain | NCT00981578 | Bone Metastases | ExAblate 2100 | 18 Years - | InSightec | |
| Prospective Evaluation of Interventional Studies on Bone Metastases - the PRESENT Cohort | NCT02356497 | Bone Metastases | 18 Years - | UMC Utrecht | ||
| A Phase IIa. Open-label, Multicenter, Dose-escalation Study to Assess the Tolerability and Pharmacokinetics of ZD4054 (Zibotentan) Given Orally Once Daily in Subjects With Metastatic Prostate Cancer | NCT00055471 | Prostatic Neopl... Metastases, Neo... | ZD4054 10 mg ZD4054 15 mg ZD4054 22.5 mg | 18 Years - | AstraZeneca | |
| BAY88-8223, Alpharadin, Breast Cancer Patients With Bone Dominant Disease | NCT01070485 | Breast Cancer Bone Metastases | Radium-223 chlo... | 21 Years - | Bayer | |
| A Trial of Strontium +/- Cisplatin for the Palliation of Bone Pain Secondary to Hormone Refractory Prostate Cancer | NCT00156884 | Hormone Refract... Bone Metastases | strontium-89 cisplatin | 18 Years - | AHS Cancer Control Alberta | |
| Efficacy and Safety of Zoledronic Acid in the Treatment of Bone Metastases-related Pain in Patients With Prostate Cancer | NCT00375648 | Pain | Zoledronic acid | 18 Years - | Novartis | |
| CTC in Lung Caner Patients With Bone Metastases | NCT04568291 | Lung Cancer Bone Metastases Single Cell Seq... | model treatment routine treatme... | 18 Years - 75 Years | Shanghai 6th People's Hospital | |
| Sipuleucel-T With or Without Radiation Therapy in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer | NCT01807065 | Adenocarcinoma ... Bone Metastases Hormone-resista... Recurrent Prost... Soft Tissue Met... Stage IV Prosta... | sipuleucel-T external beam r... laboratory biom... | 18 Years - | City of Hope Medical Center | |
| Is Bone Scintigraphy Necessary in cT1N0M0 GGO Non-Small Cell Lung Cancer? (ECTOP-1006) | NCT03689439 | Bone Metastases | bone scintigrap... | 18 Years - 80 Years | Fudan University | |
| Morphine After Radiofrequency Ablation of Painful Bone Metastases in Patients With Cancer | NCT00712712 | Metastatic Canc... Pain Unspecified Adu... | Acetaminophen Morphine Sulfat... Questionnaire a... Quality-of-life... Radiofrequency ... | 18 Years - 75 Years | Institut Bergonié | |
| Dose-finding, Safety and Efficacy Study of Radium-223 Dichloride (XOFIGO) in RCC Patients With Bone Metastases. (EIFFEL) | NCT02880943 | Clear-cell Meta... Bone Metastases | XOFIGO | 18 Years - | Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie | |
| Open Label Extension In Cancer Patients | NCT00830180 | Neoplasms Bone Metastases | Anti-NGF AB | 18 Years - | Pfizer | |
| Stereotactic Body Radiotherapy for Osseous Low Alpha-Beta Resistant Metastases for Pain Relief | NCT04177056 | Bone Metastases Prostate Cancer Breast Cancer Renal Cell Carc... Melanoma | SBRT | 18 Years - | Hamilton Health Sciences Corporation | |
| Radiofrequency Ablation in Relieving Pain in Patients With Bones Metastases | NCT00029029 | Metastatic Canc... Pain | pain therapy radiofrequency ... | 18 Years - 120 Years | Mayo Clinic | |
| Copper Cu 64-DOTA-Trastuzumab PET in Predicting Response to Treatment With Ado-Trastuzumab Emtansine in Patients With Metastatic HER2 Positive Breast Cancer | NCT02226276 | Bone Metastases HER2-positive B... Liver Metastase... Lung Metastases Recurrent Breas... Soft Tissue Met... Stage IV Breast... | fludeoxyglucose... positron emissi... computed tomogr... trastuzumab copper Cu 64-DO... positron emissi... ado-trastuzumab... laboratory biom... | 18 Years - | City of Hope Medical Center | |
| Study of Zoledronic Acid for Patients With Hormone-sensitive Bone Metastases From Prostate Cancer | NCT00242567 | Prostate Cancer | Zoledronic Acid Androgen Depriv... | 18 Years - | Novartis | |
| TEAS for the Treatment of Pain in Bone Metastases of Lung Cancer | NCT05730972 | Cancer Pain Non Small Cell ... Bone Metastases Acupuncture | Transcutaneous ... Sham transcutan... Routine palliat... | 18 Years - 80 Years | The Third Affiliated hospital of Zhejiang Chinese Medical University | |
| Dexamethasone for Pain Flare After Radiotherapy of Painful Bone metastasesZonMW 11510009 | NCT01669499 | Bone Metastases | Dexamethasone a... Placebo | 18 Years - | UMC Utrecht | |
| clinIcal Efficacy and Safety of Incadronate in Breast Cancer With Bone Metastases | NCT06392217 | Breast Cancer Bone Metastases | 18 Years - | Fudan University | ||
| Feasibility of Combined Focused Ultrasound and Radiotherapy Treatment in Patients With Painful Bone Metastasis | NCT04310410 | Bone Metastases Bone Neoplasm Bone Lesion Bone Cancer Pain Cancer Induced ... Radiation Toxic... Quality of Life Tumor Neoplasm Metast... | combined radiot... | 18 Years - | UMC Utrecht | |
| Long Term Efficacy and Safety of Zoledronic Acid Treatment in Patients With Bone Metastases | NCT00434447 | Bone Neoplasms | Zoledronic acid | 18 Years - | Novartis | |
| MRI Guided HIFU for Palliation of Painful Skeletal Metastases in Children | NCT02616016 | Bone Metastases Pain | MRI Guided High... | 5 Years - 17 Years | The Hospital for Sick Children | |
| National Database of Bone Metastases | NCT06367491 | Bone Metastases | Registration in... | 18 Years - | Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori | |
| Merestinib on Bone Metastases in Subjects With Breast Cancer | NCT03292536 | Bone Metastases Breast Cancer | Merestinib | 18 Years - | University of Utah | |
| Prospective PRO/QoL Registry for Patients With Bone Metastases of Breast or Prostate Cancer | NCT02410044 | Breast Cancer Prostate Cancer Bone Metastases | 18 Years - | iOMEDICO AG | ||
| Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases | NCT01461265 | Pain Neoplasm Metast... | Cryoablation | 18 Years - | Boston Scientific Corporation |
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