Spots Global Cancer Trial Database for Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer
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Trial Identification
Brief Title: Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer
Official Title: Randomised Phase 3 Trial of Enzalutamide in Androgen Deprivation Therapy With Radiation Therapy for High Risk, Clinically Localised, Prostate Cancer: ENZARAD
Study ID: NCT02446444
Conditions
Study Description
Brief Summary: The purpose of this study is to determine the effectiveness of enzalutamide as part of adjuvant androgen deprivation therapy (ADT) with a luteinizing hormone releasing hormone analogue (LHRHA) in men having radiation therapy for localised prostate cancer at high risk of recurrence.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: MALE
Healthy Volunteers: No
Locations
Dana Farber Cancer Institute, Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States
Blacktown Hospital, Blacktown, New South Wales, Australia
Campbelltown Hospital, Campbelltown, New South Wales, Australia
Chris O'Brien Lifehouse, Camperdown, New South Wales, Australia
Genesis Cancer Care Newcastle, Gateshead, New South Wales, Australia
Gosford Hospital, Gosford, New South Wales, Australia
St George Hospital, Kogarah, New South Wales, Australia
Liverpool Hospital, Liverpool, New South Wales, Australia
Orange Health Service, Orange, New South Wales, Australia
Prince of Wales Hospital, Randwick, New South Wales, Australia
Royal North Shore Hospital, St Leonards, New South Wales, Australia
St Vincent's Hospital, Sydney, New South Wales, Australia
Tamworth Rural Referral Hospital, Tamworth, New South Wales, Australia
Sydney Adventist Hospital, Wahroonga, New South Wales, Australia
Calvary Mater Newcastle, Waratah, New South Wales, Australia
Westmead Hospital, Westmead, New South Wales, Australia
Wollongong Hospital, Wollongong, New South Wales, Australia
Genesis Cancer Care Queensland - Wesley and Chermside, Auchenflower, Queensland, Australia
Townsville Hospital, Douglas, Queensland, Australia
Royal Brisbane & Womens Hospital, Herston, Queensland, Australia
Nambour General Hospital, Nambour, Queensland, Australia
Radiation Oncology Services Mater Centre, South Brisbane, Queensland, Australia
ICON - Gold Coast (formerly ROC Gold Coast), Southport, Queensland, Australia
ICON - Toowoomba (formerly ROC Toowoomba), Toowoomba, Queensland, Australia
Genesis Cancer Care Queensland - Tugun and Southport, Tugun, Queensland, Australia
Princess Alexandra Hospital Brisbane, Woolloongabba, Queensland, Australia
Royal Adelaide Hospital, Adelaide, South Australia, Australia
Flinders Medical Centre, Bedford Park, South Australia, Australia
Ashford Cancer Centre Research (Adelaide Cancer Centre), Kurralta Park, South Australia, Australia
Royal Hobart Hospital, Hobart, Tasmania, Australia
Peter MacCallum Cancer Centre, Bendigo, Victoria, Australia
Peter MacCallum Cancer Centre (Moorabbin Campus), Bentleigh East, Victoria, Australia
Eastern Health (Box Hill Hospital), Box Hill, Victoria, Australia
Genesis Care - Epping (formerly EROC), Epping, Victoria, Australia
Genesis Care - Western (formerly WROC), Footscray, Victoria, Australia
Genesis Care - Frankston (formerly FROC), Frankston, Victoria, Australia
Austin Health, Heidelberg, Victoria, Australia
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Epworth HealthCare - Richmond, Richmond, Victoria, Australia
Genesis Care - Ringwood (formerly RROC), Ringwood East, Victoria, Australia
Sunshine Hospital, St Albans, Victoria, Australia
Fiona Stanley Hospital, Murdoch, Western Australia, Australia
Salzburger Landeskliniken - Universitätsklinikum Salzburg, Salzburg, , Austria
AZ Groeninge Kortrijk- Campus Kennedylaan, Kortrijk, , Belgium
Cork University Hospital, Cork, Co Cork, Ireland
Galway University Hospital, Galway, Co Galway, Ireland
Mater Misericordiae University Hospital, Dublin, Dublin 7, Ireland
Beacon Private Hospital, Dublin, , Ireland
St Luke's Hospital, Dublin, , Ireland
Mater Private Hospital, Dublin, , Ireland
Auckland City Hospital, Auckland, , New Zealand
Christchurch Hospital, Christchurch, , New Zealand
Palmerston North Hospital, Palmerston North, , New Zealand
The Institute Of Oncology, Ljubljana, , Slovenia
Institut Catala d'Oncologia - ICO Badalona - Hospital Germans Trias i Pujol (Institut Catala D'Oncologia), Badalona, Barcelona, Spain
Hospital Donostia, Donostia, Gipuzkoa, Spain
Hospital Universitario de Salamanca, Salamanca, , Spain
Velindre Hospital, Whitchurch, Cardiff, United Kingdom
University Hospital Southhampton, Southampton, Hampshire, United Kingdom
Kent and Canterbury Hospital, Canterbury, Kent, United Kingdom
Royal Marsden Hospital, Chelsea, London, United Kingdom
Western General Hospital, Edinburgh, Scotland, United Kingdom
Royal United Hospital Bath, Bath, , United Kingdom
Addenbrookes Hospital, Cambridge, , United Kingdom
University of London Hospital, London, , United Kingdom
Guys and St Thomas Hospital, London, , United Kingdom
Charring Cross Hospital: Imperial College Healthcare NHS Trust, London, , United Kingdom
Nottingham City Hospital- City Campus, Nottingham, , United Kingdom
Contact Details
Name: Scott Williams
Affiliation: ANZUP and Peter MacCallum Cancer Centre
Role: STUDY_CHAIR
Name: Paul Nguyen
Affiliation: Dana Farber Cancer Institute and ANZUP
Role: STUDY_CHAIR
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