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Spots Global Cancer Trial Database for Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

Official Title: Randomized Phase II Study: Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases

Study ID: NCT02490878

Study Description

Brief Summary: This randomized phase II study aims to investigate whether the addition of bevacizumab to standard corticosteroid therapy results in greater improvement in symptoms and less treatment-induced symptoms compared with standard corticosteroid therapy for patients with symptomatic brain radionecrosis following radiosurgery. It is hypothesized that the addition of bevacizumab to standard care corticosteroids will reduce treatment-induced toxicities and improve neurologic impairments in patients with brain radionecrosis following radiosurgery for brain metastases.

Detailed Description: This is a randomized double-blinded phase II study of corticosteroids with bevacizumab vs. corticosteroids with placebo for brain radionecrosis following radiosurgery for brain metastases. This is a two-arm clinical trial with parallel group design for longitudinal quality of life endpoint. Patients will be stratified according to age (≤ 65 years vs. \> 65 years), pathological confirmation of necrosis (yes vs. no), MDASI-BT mean global score (symptom + interference scores) ( \< 4.0 vs. \> 4.0) and prior whole brain radiotherapy (yes vs. no). The primary and secondary objectives are detailed below. Primary Objective: To investigate whether the addition of bevacizumab to standard corticosteroid therapy results in greater improvement in symptoms (clinical and patient-reported symptom improvement associated with radionecrosis and less radionecrosis treatment-induced symptoms) compared with standard corticosteroid therapy. Secondary Objectives: 1. To evaluate the toxicity profile associated with bevacizumab and corticosteroid therapy. 2. To compare self-reported health related quality of life (HRQOL) using LASA, Dexamethasone Symptoms Questionnaire-Chronic (DSQ-C), and MDASI-BT symptom and interference score between treatment arms. 3. To compare intracranial progression-free survival and time to maximum radiographic response between treatment arms. 4. To compare the dose and duration of corticosteroids required between treatment arms and correlate steroid requirement with DSQ-C and MDASI-BT scores. Patient event monitoring will occur every 2 months after treatment up to 6 months. Then event monitoring will occur up to one year.

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States

Anchorage Radiation Therapy Center, Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States

Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States

Alaska Women's Cancer Care, Anchorage, Alaska, United States

Anchorage Oncology Centre, Anchorage, Alaska, United States

Katmai Oncology Group, Anchorage, Alaska, United States

Providence Alaska Medical Center, Anchorage, Alaska, United States

PCR Oncology, Arroyo Grande, California, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States

UC San Diego Moores Cancer Center, La Jolla, California, United States

Beebe Medical Center, Lewes, Delaware, United States

Delaware Clinical and Laboratory Physicians PA, Newark, Delaware, United States

Helen F Graham Cancer Center, Newark, Delaware, United States

Medical Oncology Hematology Consultants PA, Newark, Delaware, United States

Regional Hematology and Oncology PA, Newark, Delaware, United States

Christiana Care Health System-Christiana Hospital, Newark, Delaware, United States

Beebe Health Campus, Rehoboth Beach, Delaware, United States

Nanticoke Memorial Hospital, Seaford, Delaware, United States

Christiana Care Health System-Wilmington Hospital, Wilmington, Delaware, United States

Boca Raton Regional Hospital, Boca Raton, Florida, United States

Halifax Health Medical Center-Centers for Oncology, Daytona Beach, Florida, United States

Baptist MD Anderson Cancer Center, Jacksonville, Florida, United States

Mayo Clinic in Florida, Jacksonville, Florida, United States

Moffitt Cancer Center, Tampa, Florida, United States

University Cancer and Blood Center LLC, Athens, Georgia, United States

Emory University Hospital/Winship Cancer Institute, Atlanta, Georgia, United States

Memorial Health University Medical Center, Savannah, Georgia, United States

Summit Cancer Care-Memorial, Savannah, Georgia, United States

Low Country Cancer Care Associates PC, Savannah, Georgia, United States

Summit Cancer Care-Candler, Savannah, Georgia, United States

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho, United States

Saint Luke's Mountain States Tumor Institute, Boise, Idaho, United States

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho, United States

Kootenai Medical Center, Coeur d'Alene, Idaho, United States

Walter Knox Memorial Hospital, Emmett, Idaho, United States

Saint Luke's Mountain States Tumor Institute - Fruitland, Fruitland, Idaho, United States

Idaho Urologic Institute-Meridian, Meridian, Idaho, United States

Saint Luke's Mountain States Tumor Institute - Meridian, Meridian, Idaho, United States

Saint Alphonsus Medical Center-Nampa, Nampa, Idaho, United States

Saint Luke's Mountain States Tumor Institute - Nampa, Nampa, Idaho, United States

Kootenai Cancer Center, Post Falls, Idaho, United States

Kootenai Cancer Clinic, Sandpoint, Idaho, United States

Saint Luke's Mountain States Tumor Institute-Twin Falls, Twin Falls, Idaho, United States

Rush - Copley Medical Center, Aurora, Illinois, United States

Rush University Medical Center, Chicago, Illinois, United States

University of Illinois, Chicago, Illinois, United States

Carle on Vermilion, Danville, Illinois, United States

Carle Physician Group-Effingham, Effingham, Illinois, United States

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois, United States

Good Samaritan Regional Health Center, Mount Vernon, Illinois, United States

Carle Cancer Center, Urbana, Illinois, United States

The Carle Foundation Hospital, Urbana, Illinois, United States

Rush-Copley Healthcare Center, Yorkville, Illinois, United States

Deaconess Clinic Downtown, Evansville, Indiana, United States

Community Cancer Center East, Indianapolis, Indiana, United States

Community Cancer Center South, Indianapolis, Indiana, United States

Community Cancer Center North, Indianapolis, Indiana, United States

Community Howard Regional Health, Kokomo, Indiana, United States

Memorial Regional Cancer Center Day Road, Mishawaka, Indiana, United States

Chancellor Center for Oncology, Newburgh, Indiana, United States

Reid Health, Richmond, Indiana, United States

Memorial Hospital of South Bend, South Bend, Indiana, United States

Iowa Methodist Medical Center, Des Moines, Iowa, United States

Medical Oncology and Hematology Associates-Des Moines, Des Moines, Iowa, United States

Broadlawns Medical Center, Des Moines, Iowa, United States

Iowa Lutheran Hospital, Des Moines, Iowa, United States

Trinity Regional Medical Center, Fort Dodge, Iowa, United States

Methodist West Hospital, West Des Moines, Iowa, United States

Central Care Cancer Center - Garden City, Garden City, Kansas, United States

Central Care Cancer Center - Great Bend, Great Bend, Kansas, United States

Kansas Institute of Medicine Cancer and Blood Center, Lenexa, Kansas, United States

Minimally Invasive Surgery Hospital, Lenexa, Kansas, United States

Menorah Medical Center, Overland Park, Kansas, United States

Saint Luke's South Hospital, Overland Park, Kansas, United States

Mercy Medical Center, Springfield, Massachusetts, United States

Saint Joseph Mercy Hospital, Ann Arbor, Michigan, United States

University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States

IHA Hematology Oncology Consultants-Brighton, Brighton, Michigan, United States

Saint Joseph Mercy Brighton, Brighton, Michigan, United States

IHA Hematology Oncology Consultants-Canton, Canton, Michigan, United States

Saint Joseph Mercy Canton, Canton, Michigan, United States

Caro Cancer Center, Caro, Michigan, United States

IHA Hematology Oncology Consultants-Chelsea, Chelsea, Michigan, United States

Saint Joseph Mercy Chelsea, Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston, Clarkston, Michigan, United States

Newland Medical Associates-Clarkston, Clarkston, Michigan, United States

Beaumont Hospital-Dearborn, Dearborn, Michigan, United States

Ascension Saint John Hospital, Detroit, Michigan, United States

Great Lakes Cancer Management Specialists-Doctors Park, East China Township, Michigan, United States

Beaumont Hospital - Farmington Hills, Farmington Hills, Michigan, United States

Genesee Cancer and Blood Disease Treatment Center, Flint, Michigan, United States

Genesee Hematology Oncology PC, Flint, Michigan, United States

Genesys Hurley Cancer Institute, Flint, Michigan, United States

Hurley Medical Center, Flint, Michigan, United States

Great Lakes Cancer Management Specialists-Van Elslander Cancer Center, Grosse Pointe Woods, Michigan, United States

Lymphoma Clinic of Michigan, Grosse Pointe Woods, Michigan, United States

Michigan Breast Specialists-Grosse Pointe Woods, Grosse Pointe Woods, Michigan, United States

William Beaumont Hospital-Grosse Point, Grosse Pointe, Michigan, United States

Allegiance Health, Jackson, Michigan, United States

Sparrow Hospital, Lansing, Michigan, United States

Hope Cancer Clinic, Livonia, Michigan, United States

Saint Mary Mercy Hospital, Livonia, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Medical Campus, Macomb, Michigan, United States

Michigan Breast Specialists-Macomb Township, Macomb, Michigan, United States

Saint Mary's Oncology/Hematology Associates of Marlette, Marlette, Michigan, United States

Ascension Providence Hospitals - Novi, Novi, Michigan, United States

21st Century Oncology-Pontiac, Pontiac, Michigan, United States

Hope Cancer Center, Pontiac, Michigan, United States

Newland Medical Associates-Pontiac, Pontiac, Michigan, United States

Saint Joseph Mercy Oakland, Pontiac, Michigan, United States

Huron Medical Center PC, Port Huron, Michigan, United States

Lake Huron Medical Center, Port Huron, Michigan, United States

Great Lakes Cancer Management Specialists-Rochester Hills, Rochester Hills, Michigan, United States

Michigan Cancer Specialists, Roseville, Michigan, United States

Oakland Colon and Rectal Association, Royal Oak, Michigan, United States

Cancer Care Associates PC, Royal Oak, Michigan, United States

Comprehensive Medical Center PLLC, Royal Oak, Michigan, United States

Hematology Oncology Consultants PC, Royal Oak, Michigan, United States

Oakland Medical Group, Royal Oak, Michigan, United States

William Beaumont Hospital-Royal Oak, Royal Oak, Michigan, United States

Saint Mary's of Michigan, Saginaw, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC, Saginaw, Michigan, United States

Ascension Providence Hospitals - Southfield, Southfield, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights, Sterling Heights, Michigan, United States

Premier Hematology Oncology Care, Sterling Heights, Michigan, United States

Mitchell Folbe MD PC, Sterling Heights, Michigan, United States

Saint Joseph Health System-Tawas City, Tawas City, Michigan, United States

Michigan Institute of Urology-Town Center, Troy, Michigan, United States

Claudia BR Herke MD PC, Troy, Michigan, United States

William Beaumont Hospital - Troy, Troy, Michigan, United States

Hematology Oncology Consultants PC-Troy, Troy, Michigan, United States

Advanced Breast Care Center PLLC, Warren, Michigan, United States

Bhadresh Nayak MD PC-Warren, Warren, Michigan, United States

Great Lakes Cancer Management Specialists-Macomb Professional Building, Warren, Michigan, United States

Macomb Hematology Oncology PC, Warren, Michigan, United States

Michigan Breast Specialists-Warren, Warren, Michigan, United States

Saint John Macomb-Oakland Hospital, Warren, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan, United States

Huron Gastroenterology PC, Ypsilanti, Michigan, United States

IHA Hematology Oncology Consultants-Ann Arbor, Ypsilanti, Michigan, United States

Essentia Health Saint Joseph's Medical Center, Brainerd, Minnesota, United States

Essentia Health - Deer River Clinic, Deer River, Minnesota, United States

Essentia Health Saint Mary's - Detroit Lakes Clinic, Detroit Lakes, Minnesota, United States

Essentia Health Cancer Center, Duluth, Minnesota, United States

Essentia Health Saint Mary's Medical Center, Duluth, Minnesota, United States

Miller-Dwan Hospital, Duluth, Minnesota, United States

Lake Region Healthcare Corporation-Cancer Care, Fergus Falls, Minnesota, United States

Essentia Health - Fosston, Fosston, Minnesota, United States

Essentia Health Hibbing Clinic, Hibbing, Minnesota, United States

Essentia Health - Park Rapids, Park Rapids, Minnesota, United States

Mayo Clinic, Rochester, Minnesota, United States

Essentia Health Sandstone, Sandstone, Minnesota, United States

Essentia Health Virginia Clinic, Virginia, Minnesota, United States

Saint Louis Cancer and Breast Institute-Ballwin, Ballwin, Missouri, United States

Central Care Cancer Center - Bolivar, Bolivar, Missouri, United States

Cox Cancer Center Branson, Branson, Missouri, United States

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri, United States

Centerpoint Medical Center LLC, Independence, Missouri, United States

Freeman Health System, Joplin, Missouri, United States

Mercy Hospital Joplin, Joplin, Missouri, United States

Saint Luke's Hospital of Kansas City, Kansas City, Missouri, United States

Research Medical Center, Kansas City, Missouri, United States

Saint Luke's East - Lee's Summit, Lee's Summit, Missouri, United States

Delbert Day Cancer Institute at PCRMC, Rolla, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology, Rolla, Missouri, United States

Heartland Regional Medical Center, Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States

Washington University School of Medicine, Saint Louis, Missouri, United States

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri, United States

Mercy Hospital Springfield, Springfield, Missouri, United States

CoxHealth South Hospital, Springfield, Missouri, United States

Mercy Hospital Washington, Washington, Missouri, United States

Community Hospital of Anaconda, Anaconda, Montana, United States

Billings Clinic Cancer Center, Billings, Montana, United States

Bozeman Deaconess Hospital, Bozeman, Montana, United States

Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States

Great Falls Clinic, Great Falls, Montana, United States

Saint Peter's Community Hospital, Helena, Montana, United States

Kalispell Regional Medical Center, Kalispell, Montana, United States

Community Medical Hospital, Missoula, Montana, United States

Carson Tahoe Regional Medical Center, Carson City, Nevada, United States

Cancer and Blood Specialists-Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Horizon Ridge, Henderson, Nevada, United States

Las Vegas Cancer Center-Henderson, Henderson, Nevada, United States

Nevada Cancer Specialists-Saint Rose, Henderson, Nevada, United States

21st Century Oncology-Henderson, Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada-Southeast Henderson, Henderson, Nevada, United States

Desert West Surgery, Las Vegas, Nevada, United States

Nevada Cancer Specialists?Oakey, Las Vegas, Nevada, United States

University Medical Center of Southern Nevada, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Shadow, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Central, Las Vegas, Nevada, United States

21st Century Oncology, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-San Martin, Las Vegas, Nevada, United States

Radiation Oncology Centers of Nevada Southeast, Las Vegas, Nevada, United States

Cancer Therapy and Integrative Medicine, Las Vegas, Nevada, United States

21st Century Oncology-Vegas Tenaya, Las Vegas, Nevada, United States

Ann M Wierman MD LTD, Las Vegas, Nevada, United States

Cancer and Blood Specialists-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Northwest, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Tenaya, Las Vegas, Nevada, United States

Nevada Cancer Specialists-Tenaya, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada-Summerlin, Las Vegas, Nevada, United States

Summerlin Hospital Medical Center, Las Vegas, Nevada, United States

Las Vegas Cancer Center-Medical Center, Las Vegas, Nevada, United States

21st Century Oncology-Fort Apache, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada, Las Vegas, Nevada, United States

Nevada Cancer Specialists-Fort Apache, Las Vegas, Nevada, United States

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills, Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central Valley, Las Vegas, Nevada, United States

University Cancer Center, Las Vegas, Nevada, United States

Hope Cancer Care of Nevada-Pahrump, Pahrump, Nevada, United States

Renown Regional Medical Center, Reno, Nevada, United States

Saint Mary's Regional Medical Center, Reno, Nevada, United States

Radiation Oncology Associates, Reno, Nevada, United States

New Hampshire Oncology Hematology PA-Concord, Concord, New Hampshire, United States

New Hampshire Oncology Hematology PA-Hooksett, Hooksett, New Hampshire, United States

Englewood Hospital and Medical Center, Englewood, New Jersey, United States

Overlook Hospital, Summit, New Jersey, United States

Roswell Park Cancer Institute, Buffalo, New York, United States

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York, United States

University of Rochester, Rochester, New York, United States

Randolph Hospital, Asheboro, North Carolina, United States

Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States

Southeastern Medical Oncology Center-Clinton, Clinton, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina, United States

Wayne Memorial Hospital, Goldsboro, North Carolina, United States

Cone Health Cancer Center, Greensboro, North Carolina, United States

East Carolina University, Greenville, North Carolina, United States

Onslow Memorial Hospital, Jacksonville, North Carolina, United States

Southeastern Medical Oncology Center-Jacksonville, Jacksonville, North Carolina, United States

Cone Heath Cancer Center at Mebane, Mebane, North Carolina, United States

Annie Penn Memorial Hospital, Reidsville, North Carolina, United States

Southeastern Medical Oncology Center-Wilson, Wilson, North Carolina, United States

Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States

Essentia Health Cancer Center-South University Clinic, Fargo, North Dakota, United States

Essentia Health - Jamestown Clinic, Jamestown, North Dakota, United States

Cleveland Clinic Akron General, Akron, Ohio, United States

Indu and Raj Soin Medical Center, Beavercreek, Ohio, United States

Dayton Physicians LLC-Miami Valley South, Centerville, Ohio, United States

Miami Valley Hospital South, Centerville, Ohio, United States

Oncology Hematology Care Inc-Kenwood, Cincinnati, Ohio, United States

Good Samaritan Hospital - Dayton, Dayton, Ohio, United States

Miami Valley Hospital, Dayton, Ohio, United States

Dayton Physicians LLC-Samaritan North, Dayton, Ohio, United States

Miami Valley Hospital North, Dayton, Ohio, United States

Armes Family Cancer Center, Findlay, Ohio, United States

Blanchard Valley Hospital, Findlay, Ohio, United States

Orion Cancer Care, Findlay, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States

Dayton Physicians LLC-Atrium, Franklin, Ohio, United States

Dayton Physicians LLC-Wayne, Greenville, Ohio, United States

Wayne Hospital, Greenville, Ohio, United States

Greater Dayton Cancer Center, Kettering, Ohio, United States

First Dayton Cancer Care, Kettering, Ohio, United States

Kettering Medical Center, Kettering, Ohio, United States

Dayton Physicians LLC-Signal Point, Middletown, Ohio, United States

Dayton Physicians LLC-Wilson, Sidney, Ohio, United States

Springfield Regional Cancer Center, Springfield, Ohio, United States

Springfield Regional Medical Center, Springfield, Ohio, United States

Dayton Physicians LLC-Upper Valley, Troy, Ohio, United States

Upper Valley Medical Center, Troy, Ohio, United States

Mercy Hospital Oklahoma City, Oklahoma City, Oklahoma, United States

Saint Alphonsus Medical Center-Baker City, Baker City, Oregon, United States

Saint Charles Health System, Bend, Oregon, United States

Clackamas Radiation Oncology Center, Clackamas, Oregon, United States

Providence Oncology and Hematology Care Southeast, Clackamas, Oregon, United States

Bay Area Hospital, Coos Bay, Oregon, United States

Providence Newberg Medical Center, Newberg, Oregon, United States

Saint Alphonsus Medical Center-Ontario, Ontario, Oregon, United States

Providence Willamette Falls Medical Center, Oregon City, Oregon, United States

Providence Portland Medical Center, Portland, Oregon, United States

Providence Saint Vincent Medical Center, Portland, Oregon, United States

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg, Bethlehem, Pennsylvania, United States

Christiana Care Health System-Concord Health Center, Chadds Ford, Pennsylvania, United States

Roper Hospital, Charleston, South Carolina, United States

Charleston Hematology Oncology Associates-Roper, Charleston, South Carolina, United States

Lowcountry Hematology Oncology PA-North Charleston, Charleston, South Carolina, United States

Bon Secours Saint Francis Hospital, Charleston, South Carolina, United States

Charleston Hematology Oncology Associates PA-Saint Francis, Charleston, South Carolina, United States

Lowcountry Hematology Oncology PA-West Ashley, Charleston, South Carolina, United States

Greenville Health System Cancer Institute-Laurens, Clinton, South Carolina, United States

Greenville Health System Cancer Institute-Easley, Easley, South Carolina, United States

Greenville Health System Cancer Institute-Butternut, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Faris, Greenville, South Carolina, United States

Greenville Memorial Hospital, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Eastside, Greenville, South Carolina, United States

Greenville Health System Cancer Institute-Greer, Greer, South Carolina, United States

Lowcountry Hematology Oncology PA-Mount Pleasant, Mount Pleasant, South Carolina, United States

Greenville Health System Cancer Institute-Seneca, Seneca, South Carolina, United States

Greenville Health System Cancer Institute-Spartanburg, Spartanburg, South Carolina, United States

Vanderbilt-Ingram Cancer Center Cool Springs, Franklin, Tennessee, United States

Vanderbilt Breast Center at One Hundred Oaks, Nashville, Tennessee, United States

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee, United States

M D Anderson Cancer Center, Houston, Texas, United States

Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States

Cancer Care Center at Island Hospital, Anacortes, Washington, United States

PeaceHealth Saint Joseph Medical Center, Bellingham, Washington, United States

Providence Regional Cancer System-Centralia, Centralia, Washington, United States

Swedish Medical Center-Edmonds, Edmonds, Washington, United States

Providence Regional Cancer Partnership, Everett, Washington, United States

Swedish Cancer Institute-Issaquah, Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology, Kennewick, Washington, United States

Providence Regional Cancer System-Lacey, Lacey, Washington, United States

PeaceHealth Saint John Medical Center, Longview, Washington, United States

Pacific Gynecology Specialists, Seattle, Washington, United States

Swedish Medical Center-Ballard Campus, Seattle, Washington, United States

Kaiser Permanente Washington, Seattle, Washington, United States

Swedish Medical Center-First Hill, Seattle, Washington, United States

Swedish Medical Center-Cherry Hill, Seattle, Washington, United States

Providence Regional Cancer System-Shelton, Shelton, Washington, United States

Rockwood Clinic Cancer Treatment Center-Valley, Spokane Valley, Washington, United States

Rockwood Cancer Treatment Center-DHEC-Downtown, Spokane, Washington, United States

Rockwood North Cancer Treatment Center, Spokane, Washington, United States

PeaceHealth Southwest Medical Center, Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States

Providence Regional Cancer System-Yelm, Yelm, Washington, United States

United Hospital Center, Bridgeport, West Virginia, United States

WVUH-Berkely Medical Center, Martinsburg, West Virginia, United States

West Virginia University Healthcare, Morgantown, West Virginia, United States

Camden Clark Medical Center, Parkersburg, West Virginia, United States

Ashland Memorial Medical Center, Ashland, Wisconsin, United States

Duluth Clinic Ashland, Ashland, Wisconsin, United States

University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

Billings Clinic-Cody, Cody, Wyoming, United States

Welch Cancer Center, Sheridan, Wyoming, United States

BCCA-Vancouver Cancer Centre, Vancouver, British Columbia, Canada

Juravinski Cancer Centre at Hamilton Health Sciences, Hamilton, Ontario, Canada

Ottawa Hospital and Cancer Center-General Campus, Ottawa, Ontario, Canada

Odette Cancer Centre- Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

University Health Network-Princess Margaret Hospital, Toronto, Ontario, Canada

CHUM - Hopital Notre-Dame, Montreal, Quebec, Canada

CHUM - Centre Hospitalier de l'Universite de Montreal, Montreal, Quebec, Canada

Jewish General Hospital, Montreal, Quebec, Canada

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec, Canada

Contact Details

Name: Caroline Chung, MD

Affiliation: M.D. Anderson Cancer Center

Role: STUDY_CHAIR

Useful links and downloads for this trial

Clinicaltrials.gov

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