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Spots Global Cancer Trial Database for Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

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We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Official Title: A Phase II Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Study ID: NCT04165772

Study Description

Brief Summary: The purpose of this study is to find out whether the study drug, TSR-042, followed by standard chemoradiotherapy (the chemotherapy drug capecitabine + radiation therapy) and standard surgery is an effective treatment for advanced dMMR solid tumors. The study will also look at the safety of the study drug.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Hartford Healthcare (Data Collection), Hartford, Connecticut, United States

Baptist Alliance MCI (Data Collection Only), Miami, Florida, United States

Memorial Sloan Kettering Basking Ridge - Limited Protocol Activities, Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth - Limited Protocol Activities, Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen - Limited Protocol Activities, Montvale, New Jersey, United States

New York Cancer and Blood Specialists, Babylon, New York, United States

Memorial Sloan Kettering Commack - Limited Protocol Activities, Commack, New York, United States

Memorial Sloan Kettering Westchester - Limited Protocol Activities, Harrison, New York, United States

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Memorial Sloan Kettering Nassau - Limited Protocol Activities, Uniondale, New York, United States

Lehigh Valley Health Network (Data Collection Only), Allentown, Pennsylvania, United States

Contact Details

Name: Andrea Cercek, MD

Affiliation: Memorial Sloan Kettering Cancer Center

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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