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Brief Title: Preoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal Cancer
Official Title: A Phase II Trial of Integrated Preoperative Radiotherapy and Chemotherapy With Oxaliplatin 5-FU and Folinic Acid in Patients With Locally Advanced Rectal Cancer
Study ID: NCT01013805
Brief Summary: The aims of the trial are (1) to determine the tolerability rate in the setting of a multi-centre study and (2) to determine secondary tolerability endpoints, toxicity rates and complete pathologic response rate in patients with locally advanced rectal cancer who are treated with an integrated preoperative radiotherapy with FOLFOX chemotherapy regimen.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Name: Sam Ngan
Affiliation: Trans Tasman Radiation Oncology Group
Role: STUDY_CHAIR