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Spots Global Cancer Trial Database for rectal cancer

Every month we try and update this database with for rectal cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal CancerNCT05461248
Rectal Cancer
stoma drainage ...
Standard of Car...
18 Years - 75 YearsThe First Hospital of Jilin University
IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study.NCT06160570
Rectal Cancer
Radiotherapy
Toxicity Due to...
Intensive Modul...
3-Dimension Con...
18 Years - Rabin Medical Center
Exploratory Study of TG02-treatment as Monotherapy or in Combination With Pembrolizumab to Assess Safety and Immune Activation in Patients With Locally Advanced Primary and Recurrent Oncogenic RAS Exon 2 Mutant Colorectal CancerNCT02933944
Rectal Cancer
TG02-treatment
Pembrolizumab
18 Years - Targovax ASA
Anastomotic Leakage After Anterior Resection of Rectal CancerNCT03281070
Rectal Cancer
- Beijing Friendship Hospital
ELRR by TEM Versus Laparoscopic TME in iT2N0M0 SMALL LOW RECTAL CANCERNCT01609504
Rectal Cancer
ELRR BY TEM
LTME
- University of Roma La Sapienza
Ketogenic Diet Compliance in Patients Affected by Locally Advanced Rectal Cancer Patients Who Undergo to RadiotherapyNCT05938322
Rectal Cancer
Ketogenic Diet
Standard Diet
18 Years - 75 YearsFondazione Policlinico Universitario Agostino Gemelli IRCCS
Induction Chemotherapy for Locally Advanced Rectal CancerNCT04838496
Rectal Cancer
FOLFOXIRI Proto...
18 Years - Catharina Ziekenhuis Eindhoven
Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal CancerNCT02353858
Rectal Cancer
Locally Advance...
Hyperthermia
Hyperthermic Ra...
Hyperthermic Ch...
Deep Regional H...
Deep regional h...
Radiotherapy
Chemotherapy (5...
18 Years - 80 YearsUniversity Hospital Tuebingen
Comparing Preoperative Short-course Radiotherapy With or Without Local Boost for Rectal CancerNCT02498353
Rectal Cancer
preoperative sh...
preoperative sh...
TME surgery
18 Years - 70 YearsZhongnan Hospital
IPC Status as a Surgical Quality Marker in Rectal Cancer SurgeryNCT02081547
Rectal Cancer
18 Years - Uppsala University
The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic LeakageNCT03325361
Rectal Cancer
Rectal Neoplasm...
Anastomotic Lea...
Tube drain inse...
- University of Rome Tor Vergata
Multicenter, Prospective, RCT:Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer.NCT03042000
Rectal Cancer, ...
Neoadjuvant Che...
non-NCRT
NCRT
capecitabine wi...
capecitabine
TEM
radical resecti...
18 Years - 75 YearsPeking Union Medical College Hospital
Comparison of Robotic Versus Laparoscopic Surgery for Visceral Obesity in Mid-Low Rectal Cancer: A Propensity-Matched AnalysisNCT06397053
Visceral Obesit...
Rectal Cancer
Robotic Surgery
robotic surgery
18 Years - 90 YearsNorthern Jiangsu People's Hospital
Promoting Physical Activity After Colorectal CancerNCT00230646
Colon Cancer
Rectal Cancer
Exercise counse...
18 Years - The Miriam Hospital
Survivor Choices for Eating and Drinking - Colorectal CancerNCT02965521
Colon Cancer
Rectal Cancer
ColoRectal Canc...
Website and tex...
18 Years - University of California, San Francisco
Trial Comparing Loop Ileostomy Versus Loop Transverse ColostomyNCT05745909
Rectal Neoplasm...
Ostomy
Neoplasms
Laparoscopic or...
Laparoscopic or...
18 Years - 79 YearsRepublican Clinical Oncological Dispensary, Ministry of Health of the Republic of Bashkortostan
Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal CancerNCT01762813
Colorectal Canc...
open and laparo...
18 Years - Helse Stavanger HF
Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal CancerNCT01186705
Colon Cancer
Rectal Cancer
MK-2206
18 Years - Memorial Sloan Kettering Cancer Center
Safety Study of 90Y-hMN14 to Treat Colorectal CancerNCT00040599
Colorectal Canc...
Colon Cancer
Rectal Cancer
Colorectal Neop...
Colorectal Carc...
Colorectal Tumo...
hMN14 (labetuzu...
18 Years - Gilead Sciences
Total Neoadjuvant Therapy of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (ENSEMBLE)NCT05646511
Locally Advance...
SCRT
CAPOX
CAPOXIRI
18 Years - National Cancer Center Hospital East
Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy in Combination With Bevacizumab-FOLFOXNCT01395667
Rectal Cancer
CCRT
20 Years - 70 YearsNational Taiwan University Hospital
Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal AdenocarcinomaNCT05858567
Rectal Cancer
Envafolimab
18 Years - Sir Run Run Shaw Hospital
Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal CancerNCT00903396
Anal Cancer
Carcinoma of th...
Colorectal Canc...
Extrahepatic Bi...
Gallbladder Can...
Gastric Cancer
Gastrointestina...
Liver Cancer
Nausea and Vomi...
Pancreatic Canc...
Primary Periton...
Small Intestine...
palonosetron hy...
placebo
18 Years - Alliance for Clinical Trials in Oncology
The Role of TextRAd on Detection of Liver Metastasis in Rectal CancerNCT05398822
Rectal Cancer
MRI
- East Suffolk and North Essex NHS Foundation Trust
Action of Synbiotics on Irradiated GI Mucosa in Rectal Cancer TreatmentNCT03420443
Rectal Cancer
Oat bran
Oat bran and bl...
No oral supplem...
18 Years - 80 YearsRegion Skane
Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer PatientsNCT03431428
Almost-cCR
Surgery
Rectal Cancer
transanal surge...
Miles surgery
Preoperative ch...
18 Years - 75 YearsLiaoning Tumor Hospital & Institute
Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on NeoantigenNCT04340401
Rectal Cancer
SHR-1210
Oxaliplatin
Capecitabine
Intensity modul...
Total mesorecta...
18 Years - 70 YearsPeking University Cancer Hospital & Institute
One Time Injection of Bacteria to Treat Solid Tumors That Have Not Responded to Standard TherapyNCT00358397
Tumors
Clostridium nov...
18 Years - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal CancerNCT05939661
Rectal Cancer
Radiation
Chemotherapy
Surgery
18 Years - Osaka University
Induction Therapy With Panitumumab + mFOLFOX-6 in Rectal Cancer and Quadruple Wild-type Mutation Before SurgeryNCT03000374
Rectal Cancer
Panitumumab
5Fluorouracil
Oxaliplatin
Leucovorin
18 Years - 74 YearsGrupo Espanol Multidisciplinario del Cancer Digestivo
Complete Pathologic Response Rectal CancersNCT03351959
Rectal Cancer
neo-adjuvant tr...
18 Years - Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant TreatmentNCT05927584
Rectal Cancer
Rectum Neoplasm
Transanal local...
18 Years - Fundación de Investigación Biomédica - Hospital Universitario de La Princesa
Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal CancerNCT04323722
Rectal Cancer
Empty Bladder p...
18 Years - Institut Cancerologie de l'Ouest
Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi)NCT06229041
Rectal Cancer
Camrelizumab +I...
18 Years - 75 YearsPeking University Cancer Hospital & Institute
MRI Guided SIB Radiotherapy in Neoadjuvant Therapy for Advanced Rectal CancerNCT06246344
Rectal Cancer
MRI Guided Simu...
18 Years - 75 YearsShandong Cancer Hospital and Institute
Evaluation of Protein in the Urine in Patients Receiving BevacizumabNCT00849394
Colon Cancer
Rectal Cancer
18 Years - North Texas Veterans Healthcare System
SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal CancerNCT04417699
Rectal Cancer
TAS 102
Oxaliplatin
18 Years - Providence Health & Services
Rectal Preserving Treatment for Early Rectal Cancer. A Multi-centred Randomised Trial of Radical Surgery Versus Adjuvant Chemoradiotherapy After Local Excision for Early Rectal CancersNCT02371304
Rectal Cancer
Adjuvant chemor...
Additional TME ...
capecitabine
18 Years - Amsterdam UMC, location VUmc
Organ Preservation in Elderly Patients With Rectal CancerNCT01863862
Rectal Cancer
Radiochemothera...
70 Years - Maria Sklodowska-Curie National Research Institute of Oncology
Pelvic Drain After Rectal Resection for Mid-low Rectal CancerNCT04573621
Rectal Cancer
Pelvic drain
No pelvic drain...
18 Years - Hospital Universitari Vall d'Hebron Research Institute
Evaluate Efficacy, Morbidity and Functional Outcome of Endoscopic TranAnal Proctectomy vs Standard Transabdominal Laparoscopic Proctectomy for Rectal CancerNCT02584985
Rectal Cancer
ETAP
Standard Transa...
18 Years - Institut Paoli-Calmettes
Carnoy's Solution Versus Formalin in Rectal and Gastric Cancer Specimens Following: a Randomized TrialNCT02629315
Rectal Cancer
Gastric Adenoca...
Carnoy's soluti...
10% neutral buf...
18 Years - 80 YearsInstituto do Cancer do Estado de São Paulo
Aspirin in Treating Patients With Colorectal Cancer That Has Been Surgically RemovedNCT00002527
Colorectal Canc...
aspirin
placebo
30 Years - 74 YearsAlliance for Clinical Trials in Oncology
A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic SurgeryNCT06369597
Liver Cancer
Renal Cancer
Rectal Cancer
Robotic telesur...
Laparoscopic su...
18 Years - 75 YearsSun Yat-sen University
Radiomics in Rectal CancerNCT05331040
Rectal Cancer
MRI
18 Years - NHS Grampian
Simple Transanal Local Excision,Transanal Local Excision Following Radiotherapy Versus Total Mesorectum Excision for the Treatment of the Ultra-low T2N0M0 Rectal CancerNCT04098471
Rectal Cancer
transanal local...
18 Years - 80 YearsThe First Affiliated Hospital with Nanjing Medical University
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)NCT06222255
Low Anterior Re...
Rectal Cancer
Insomnia
Sleep Disorder
Transanal Irrig...
19 Years - 80 YearsSeoul National University Hospital
Patient Reported Outcomes Following Cancer of the RectumNCT04936581
Sphincter Ani I...
Rectal Cancer
Open Total Meso...
Laparoscopic To...
Robotic Total M...
Transanal Total...
18 Years - 100 YearsUniversity Hospital Gregorio Marañón
Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer PatientsNCT03921684
Rectal Cancer
Capecitabine
Radiation thera...
mFOLFOX6
Nivolumab
18 Years - Rabin Medical Center
Perineal Flap Reconstruction Following Surgery for Advanced Pelvic MalignancyNCT05074082
Pelvic Cancer
Rectal Cancer
Flap Disorder
Flap Ischemia
Flap Necrosis
Perioperative C...
Flap reconstruc...
18 Years - St Vincent's University Hospital, Ireland
Patient Reported Outcomes Following Cancer of the RectumNCT04936581
Sphincter Ani I...
Rectal Cancer
Open Total Meso...
Laparoscopic To...
Robotic Total M...
Transanal Total...
18 Years - 100 YearsUniversity Hospital Gregorio Marañón
Hartmanns Procedure or Abdominoperineal Excision With Intersphincteric Dissection in Rectal Cancer: a Randomized StudyNCT01995396
Rectal Cancer
Sphincter Ani I...
Other Diagnoses...
APE with inters...
Hartmann´s proc...
18 Years - Region Västmanland
Phase II Trial of Preoperative High-dose-rate Endorectal Brachytherapy and FOLFOX Chemotherapy for Rectal CancerNCT01659424
Rectal Cancer
High Dose Rate ...
18 Years - Beth Israel Medical Center
Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal AdenocarcinomaNCT05858567
Rectal Cancer
Envafolimab
18 Years - Sir Run Run Shaw Hospital
Prevention of Acute Voiding Difficulty After Radical ProctectomyNCT00606983
Rectal Cancer
Urinary Retenti...
Tamsulosin
20 Years - 80 YearsSeoul National University Hospital
Robotic-assisted Versus Conventional Laparoscopic Approach for Rectal Cancer SurgeryNCT03589131
Rectal Cancer
Total Operative...
Margin assessme...
Conversion rate...
Baseline demogr...
Preoperative da...
Postoperative d...
16 Years - 75 YearsNational Cancer Institute, Egypt
Reinforcement of Rectal Anastomosis-RORANCT02589483
Rectal Cancer
The rectal anas...
Hemopatch
- Capio Sankt Görans Hospital
Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal CancerNCT03565029
Colo-rectal Can...
XELOX
Radiotherapy
18 Years - Niguarda Hospital
Pathology Assessment of Mesorectal Fascia After TME by Laparoscopic, Open, TransAnal and Robotic Approaches (LOTARTME)NCT04949672
Rectal Cancer
Surgery
- San Giovanni Addolorata Hospital
Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal CancerNCT00200200
Hepatic Metasta...
Colon Cancer
Rectal Cancer
Bevacizumab HAI...
HAI plus system...
19 Years - Memorial Sloan Kettering Cancer Center
Preoperative Chemoradiation With VMAT-SIB in Rectal CancerNCT02745639
Rectal Neoplasm...
VMAT-SIB
XELOX
18 Years - IRCCS Azienda Ospedaliero-Universitaria di Bologna
High Dose Radiotherapy for the Treatment of Rectal CancerNCT03541304
Rectal Cancer
18 Years - 80 YearsSun Yat-sen University
Procedure RACHEL in Complex Treatment of Rectal CancerNCT02022553
Rectal Cancer T...
usual rectal ca...
RACHEL
18 Years - 75 YearsVoronezh N.N. Burdenko State Medical Academy
Computer Navigation-assisted Surgery for Locally Advanced and Recurrent Rectal CancerNCT04512937
Rectal Cancer
Computer-assist...
18 Years - Oslo University Hospital
Functional Outcomes and Quality of Life in Patients Undergoing Surgery for Rectal CancerNCT00579579
Rectal Cancer
Questionaires
18 Years - Memorial Sloan Kettering Cancer Center
Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal CancerNCT00068692
Rectal Mucinous...
Rectal Signet R...
Recurrent Recta...
Stage IIA Recta...
Stage IIB Recta...
Stage IIC Recta...
Stage IIIA Rect...
Stage IIIB Rect...
Stage IIIC Rect...
Stage IVA Recta...
Stage IVB Recta...
Radiotherapy
Fluorouracil
Leucovorin Calc...
Oxaliplatin
Irinotecan
18 Years - National Cancer Institute (NCI)
FOLFOXIRI With or Without Intensification for Rectal CancerNCT03997435
Rectal Cancer
Control arm
Experimental ar...
18 Years - Chinese University of Hong Kong
Patient Activation Intervention in Improving Screening Rates for Colorectal CancerNCT01801059
Colon Cancer
Rectal Cancer
educational int...
educational int...
questionnaire a...
50 Years - Ohio State University Comprehensive Cancer Center
Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal CancerNCT02031939
Advanced Rectal...
Induction chemo...
standard chemor...
18 Years - 75 YearsSun Yat-sen University
Pilot Study Evaluating the Efficacy of AlloMEM After Loop IleostomyNCT01113736
Colon Cancer
Rectal Cancer
AlloMEM™
18 Years - University Hospitals Cleveland Medical Center
A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal CancerNCT05939661
Rectal Cancer
Radiation
Chemotherapy
Surgery
18 Years - Osaka University
PTC Drug Sensitivity Detection to Guide Postoperative Adjuvant of Colorectal CancerNCT05978349
Colo-rectal Can...
adjuvant therap...
18 Years - 75 YearsPeking Union Medical College Hospital
Online Adaptive Radiation Therapy for Rectal CancerNCT05911789
Rectal Cancer
Online adaptive...
18 Years - Peking Union Medical College Hospital
A Prospective Feasibility Study for TAMISNCT02626728
Rectal Cancer
laparoscopic as...
18 Years - 99 YearsHvidovre University Hospital
Capecitabine in the Perioperative Treatment of Rectal CancerNCT01500993
Rectal Cancer
Capecitabine
5-FU
18 Years - Universitätsmedizin Mannheim
A Study of Bevacizumab (Avastin) in Participants With Newly Diagnosed Locally Advanced Rectal CancerNCT00865189
Rectal Cancer
Bevacizumab
Oxaliplatin
Folinic Acid
5-fluorouracil
Preoperative Ra...
Surgery
18 Years - 75 YearsHoffmann-La Roche
High Dose Vitamin D StudyNCT01150877
Colorectal Canc...
Vitamin D
18 Years - University of British Columbia
Capecitabine and Lenvatinib With External Radiation in Rectal AdenocarcinomaNCT02935309
Rectal Cancer
Rectal Adenocar...
Lenvatinib
Capecitabine
External Radiat...
18 Years - H. Lee Moffitt Cancer Center and Research Institute
Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer SurgeryNCT02177084
Rectal Cancer
Low Anterior Re...
PTNS
18 Years - 80 YearsIRCCS Azienda Ospedaliero-Universitaria di Bologna
Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer PatientsNCT06043999
Chemotherapy Ef...
Rectal Cancer
Radical total m...
Salavge Adjuvan...
18 Years - 75 YearsSun Yat-sen University
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