Spots Global Cancer Trial Database for rectal cancer
Every month we try and update this database with for rectal cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
---|---|---|---|---|---|---|
Stoma Discharge Reinfusion After Sphincter Preservation for Middle and Low Rectal Cancer | NCT05461248 | Rectal Cancer | stoma drainage ... Standard of Car... | 18 Years - 75 Years | The First Hospital of Jilin University | |
IMRT Versus 3DCRT for Locally Advanced Rectal Cancer, Prospective Phase II Study. | NCT06160570 | Rectal Cancer Radiotherapy Toxicity Due to... | Intensive Modul... 3-Dimension Con... | 18 Years - | Rabin Medical Center | |
Exploratory Study of TG02-treatment as Monotherapy or in Combination With Pembrolizumab to Assess Safety and Immune Activation in Patients With Locally Advanced Primary and Recurrent Oncogenic RAS Exon 2 Mutant Colorectal Cancer | NCT02933944 | Rectal Cancer | TG02-treatment Pembrolizumab | 18 Years - | Targovax ASA | |
Anastomotic Leakage After Anterior Resection of Rectal Cancer | NCT03281070 | Rectal Cancer | - | Beijing Friendship Hospital | ||
ELRR by TEM Versus Laparoscopic TME in iT2N0M0 SMALL LOW RECTAL CANCER | NCT01609504 | Rectal Cancer | ELRR BY TEM LTME | - | University of Roma La Sapienza | |
Ketogenic Diet Compliance in Patients Affected by Locally Advanced Rectal Cancer Patients Who Undergo to Radiotherapy | NCT05938322 | Rectal Cancer | Ketogenic Diet Standard Diet | 18 Years - 75 Years | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
Induction Chemotherapy for Locally Advanced Rectal Cancer | NCT04838496 | Rectal Cancer | FOLFOXIRI Proto... | 18 Years - | Catharina Ziekenhuis Eindhoven | |
Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer | NCT02353858 | Rectal Cancer Locally Advance... Hyperthermia Hyperthermic Ra... Hyperthermic Ch... Deep Regional H... | Deep regional h... Radiotherapy Chemotherapy (5... | 18 Years - 80 Years | University Hospital Tuebingen | |
Comparing Preoperative Short-course Radiotherapy With or Without Local Boost for Rectal Cancer | NCT02498353 | Rectal Cancer | preoperative sh... preoperative sh... TME surgery | 18 Years - 70 Years | Zhongnan Hospital | |
IPC Status as a Surgical Quality Marker in Rectal Cancer Surgery | NCT02081547 | Rectal Cancer | 18 Years - | Uppsala University | ||
The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage | NCT03325361 | Rectal Cancer Rectal Neoplasm... Anastomotic Lea... | Tube drain inse... | - | University of Rome Tor Vergata | |
Multicenter, Prospective, RCT:Investigation of Combined Modality Therapy for Locally Advanced Mid/Low Rectal Cancer. | NCT03042000 | Rectal Cancer, ... Neoadjuvant Che... | non-NCRT NCRT capecitabine wi... capecitabine TEM radical resecti... | 18 Years - 75 Years | Peking Union Medical College Hospital | |
Comparison of Robotic Versus Laparoscopic Surgery for Visceral Obesity in Mid-Low Rectal Cancer: A Propensity-Matched Analysis | NCT06397053 | Visceral Obesit... Rectal Cancer Robotic Surgery | robotic surgery | 18 Years - 90 Years | Northern Jiangsu People's Hospital | |
Promoting Physical Activity After Colorectal Cancer | NCT00230646 | Colon Cancer Rectal Cancer | Exercise counse... | 18 Years - | The Miriam Hospital | |
Survivor Choices for Eating and Drinking - Colorectal Cancer | NCT02965521 | Colon Cancer Rectal Cancer ColoRectal Canc... | Website and tex... | 18 Years - | University of California, San Francisco | |
Trial Comparing Loop Ileostomy Versus Loop Transverse Colostomy | NCT05745909 | Rectal Neoplasm... Ostomy Neoplasms | Laparoscopic or... Laparoscopic or... | 18 Years - 79 Years | Republican Clinical Oncological Dispensary, Ministry of Health of the Republic of Bashkortostan | |
Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer | NCT01762813 | Colorectal Canc... | open and laparo... | 18 Years - | Helse Stavanger HF | |
Clinical And Translational Study Of MK-2206 In Patients With Metastatic KRAS-Wild-Type, PIK3CA-Mutated, Colorectal Cancer | NCT01186705 | Colon Cancer Rectal Cancer | MK-2206 | 18 Years - | Memorial Sloan Kettering Cancer Center | |
Safety Study of 90Y-hMN14 to Treat Colorectal Cancer | NCT00040599 | Colorectal Canc... Colon Cancer Rectal Cancer Colorectal Neop... Colorectal Carc... Colorectal Tumo... | hMN14 (labetuzu... | 18 Years - | Gilead Sciences | |
Total Neoadjuvant Therapy of SCRT+CAPOX vs SCRT+CAPOXIRI for Locally Advanced Rectal Cancer (ENSEMBLE) | NCT05646511 | Locally Advance... | SCRT CAPOX CAPOXIRI | 18 Years - | National Cancer Center Hospital East | |
Preoperative Chemoradiotherapy Utilizing Intensity Modulated Radiation Therapy in Combination With Bevacizumab-FOLFOX | NCT01395667 | Rectal Cancer | CCRT | 20 Years - 70 Years | National Taiwan University Hospital | |
Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma | NCT05858567 | Rectal Cancer | Envafolimab | 18 Years - | Sir Run Run Shaw Hospital | |
Palonosetron Hydrochloride in Preventing Nausea and Vomiting Caused by Radiation Therapy in Patients With Primary Abdominal Cancer | NCT00903396 | Anal Cancer Carcinoma of th... Colorectal Canc... Extrahepatic Bi... Gallbladder Can... Gastric Cancer Gastrointestina... Liver Cancer Nausea and Vomi... Pancreatic Canc... Primary Periton... Small Intestine... | palonosetron hy... placebo | 18 Years - | Alliance for Clinical Trials in Oncology | |
The Role of TextRAd on Detection of Liver Metastasis in Rectal Cancer | NCT05398822 | Rectal Cancer | MRI | - | East Suffolk and North Essex NHS Foundation Trust | |
Action of Synbiotics on Irradiated GI Mucosa in Rectal Cancer Treatment | NCT03420443 | Rectal Cancer | Oat bran Oat bran and bl... No oral supplem... | 18 Years - 80 Years | Region Skane | |
Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients | NCT03431428 | Almost-cCR Surgery Rectal Cancer | transanal surge... Miles surgery Preoperative ch... | 18 Years - 75 Years | Liaoning Tumor Hospital & Institute | |
Total Neoadjuvant Treatment Plus SHR1210 for High-risk Rectal Cancer and Biomarker Screening Base on Neoantigen | NCT04340401 | Rectal Cancer | SHR-1210 Oxaliplatin Capecitabine Intensity modul... Total mesorecta... | 18 Years - 70 Years | Peking University Cancer Hospital & Institute | |
One Time Injection of Bacteria to Treat Solid Tumors That Have Not Responded to Standard Therapy | NCT00358397 | Tumors | Clostridium nov... | 18 Years - | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |
A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer | NCT05939661 | Rectal Cancer | Radiation Chemotherapy Surgery | 18 Years - | Osaka University | |
Induction Therapy With Panitumumab + mFOLFOX-6 in Rectal Cancer and Quadruple Wild-type Mutation Before Surgery | NCT03000374 | Rectal Cancer | Panitumumab 5Fluorouracil Oxaliplatin Leucovorin | 18 Years - 74 Years | Grupo Espanol Multidisciplinario del Cancer Digestivo | |
Complete Pathologic Response Rectal Cancers | NCT03351959 | Rectal Cancer | neo-adjuvant tr... | 18 Years - | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | |
Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment | NCT05927584 | Rectal Cancer Rectum Neoplasm | Transanal local... | 18 Years - | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | |
Impact of Bladder Depletion on Mesorectal Movements During Radiotherapy in Rectal Cancer | NCT04323722 | Rectal Cancer | Empty Bladder p... | 18 Years - | Institut Cancerologie de l'Ouest | |
Total Neoadjuvant Treatment ±Immunotherapy for High Risk Locally Advanced Rectal Cancer (TNTi) | NCT06229041 | Rectal Cancer | Camrelizumab +I... | 18 Years - 75 Years | Peking University Cancer Hospital & Institute | |
MRI Guided SIB Radiotherapy in Neoadjuvant Therapy for Advanced Rectal Cancer | NCT06246344 | Rectal Cancer | MRI Guided Simu... | 18 Years - 75 Years | Shandong Cancer Hospital and Institute | |
Evaluation of Protein in the Urine in Patients Receiving Bevacizumab | NCT00849394 | Colon Cancer Rectal Cancer | 18 Years - | North Texas Veterans Healthcare System | ||
SHOrt Course Radiation and TASOX (TAS102 Plus Oxaliplatin) Chemotherapy in Operable Rectal Cancer | NCT04417699 | Rectal Cancer | TAS 102 Oxaliplatin | 18 Years - | Providence Health & Services | |
Rectal Preserving Treatment for Early Rectal Cancer. A Multi-centred Randomised Trial of Radical Surgery Versus Adjuvant Chemoradiotherapy After Local Excision for Early Rectal Cancers | NCT02371304 | Rectal Cancer | Adjuvant chemor... Additional TME ... capecitabine | 18 Years - | Amsterdam UMC, location VUmc | |
Organ Preservation in Elderly Patients With Rectal Cancer | NCT01863862 | Rectal Cancer | Radiochemothera... | 70 Years - | Maria Sklodowska-Curie National Research Institute of Oncology | |
Pelvic Drain After Rectal Resection for Mid-low Rectal Cancer | NCT04573621 | Rectal Cancer | Pelvic drain No pelvic drain... | 18 Years - | Hospital Universitari Vall d'Hebron Research Institute | |
Evaluate Efficacy, Morbidity and Functional Outcome of Endoscopic TranAnal Proctectomy vs Standard Transabdominal Laparoscopic Proctectomy for Rectal Cancer | NCT02584985 | Rectal Cancer | ETAP Standard Transa... | 18 Years - | Institut Paoli-Calmettes | |
Carnoy's Solution Versus Formalin in Rectal and Gastric Cancer Specimens Following: a Randomized Trial | NCT02629315 | Rectal Cancer Gastric Adenoca... | Carnoy's soluti... 10% neutral buf... | 18 Years - 80 Years | Instituto do Cancer do Estado de São Paulo | |
Aspirin in Treating Patients With Colorectal Cancer That Has Been Surgically Removed | NCT00002527 | Colorectal Canc... | aspirin placebo | 30 Years - 74 Years | Alliance for Clinical Trials in Oncology | |
A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery | NCT06369597 | Liver Cancer Renal Cancer Rectal Cancer | Robotic telesur... Laparoscopic su... | 18 Years - 75 Years | Sun Yat-sen University | |
Radiomics in Rectal Cancer | NCT05331040 | Rectal Cancer | MRI | 18 Years - | NHS Grampian | |
Simple Transanal Local Excision,Transanal Local Excision Following Radiotherapy Versus Total Mesorectum Excision for the Treatment of the Ultra-low T2N0M0 Rectal Cancer | NCT04098471 | Rectal Cancer | transanal local... | 18 Years - 80 Years | The First Affiliated Hospital with Nanjing Medical University | |
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS) | NCT06222255 | Low Anterior Re... Rectal Cancer Insomnia Sleep Disorder | Transanal Irrig... | 19 Years - 80 Years | Seoul National University Hospital | |
Patient Reported Outcomes Following Cancer of the Rectum | NCT04936581 | Sphincter Ani I... Rectal Cancer | Open Total Meso... Laparoscopic To... Robotic Total M... Transanal Total... | 18 Years - 100 Years | University Hospital Gregorio Marañón | |
Trial of Nivolumab With FOLFOX After Chemoradiation in Rectal Cancer Patients | NCT03921684 | Rectal Cancer | Capecitabine Radiation thera... mFOLFOX6 Nivolumab | 18 Years - | Rabin Medical Center | |
Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy | NCT05074082 | Pelvic Cancer Rectal Cancer Flap Disorder Flap Ischemia Flap Necrosis Perioperative C... | Flap reconstruc... | 18 Years - | St Vincent's University Hospital, Ireland | |
Patient Reported Outcomes Following Cancer of the Rectum | NCT04936581 | Sphincter Ani I... Rectal Cancer | Open Total Meso... Laparoscopic To... Robotic Total M... Transanal Total... | 18 Years - 100 Years | University Hospital Gregorio Marañón | |
Hartmanns Procedure or Abdominoperineal Excision With Intersphincteric Dissection in Rectal Cancer: a Randomized Study | NCT01995396 | Rectal Cancer Sphincter Ani I... Other Diagnoses... | APE with inters... Hartmann´s proc... | 18 Years - | Region Västmanland | |
Phase II Trial of Preoperative High-dose-rate Endorectal Brachytherapy and FOLFOX Chemotherapy for Rectal Cancer | NCT01659424 | Rectal Cancer | High Dose Rate ... | 18 Years - | Beth Israel Medical Center | |
Total Neoadjuvant Therapy With Short-course Radiation Followed by Envafolimab Plus CAPEOX for MSS Locally Advanced Ultra Low Rectal Adenocarcinoma | NCT05858567 | Rectal Cancer | Envafolimab | 18 Years - | Sir Run Run Shaw Hospital | |
Prevention of Acute Voiding Difficulty After Radical Proctectomy | NCT00606983 | Rectal Cancer Urinary Retenti... | Tamsulosin | 20 Years - 80 Years | Seoul National University Hospital | |
Robotic-assisted Versus Conventional Laparoscopic Approach for Rectal Cancer Surgery | NCT03589131 | Rectal Cancer | Total Operative... Margin assessme... Conversion rate... Baseline demogr... Preoperative da... Postoperative d... | 16 Years - 75 Years | National Cancer Institute, Egypt | |
Reinforcement of Rectal Anastomosis-RORA | NCT02589483 | Rectal Cancer | The rectal anas... Hemopatch | - | Capio Sankt Görans Hospital | |
Total Neoadjuvant Treatment Without Surgery For Locally Advanced Rectal Cancer | NCT03565029 | Colo-rectal Can... | XELOX Radiotherapy | 18 Years - | Niguarda Hospital | |
Pathology Assessment of Mesorectal Fascia After TME by Laparoscopic, Open, TransAnal and Robotic Approaches (LOTARTME) | NCT04949672 | Rectal Cancer Surgery | - | San Giovanni Addolorata Hospital | ||
Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combination With Chemotherapy With/Without Bevacizumab for Hepatic Metastases From Colorectal Cancer | NCT00200200 | Hepatic Metasta... Colon Cancer Rectal Cancer | Bevacizumab HAI... HAI plus system... | 19 Years - | Memorial Sloan Kettering Cancer Center | |
Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer | NCT02745639 | Rectal Neoplasm... | VMAT-SIB XELOX | 18 Years - | IRCCS Azienda Ospedaliero-Universitaria di Bologna | |
High Dose Radiotherapy for the Treatment of Rectal Cancer | NCT03541304 | Rectal Cancer | 18 Years - 80 Years | Sun Yat-sen University | ||
Procedure RACHEL in Complex Treatment of Rectal Cancer | NCT02022553 | Rectal Cancer T... | usual rectal ca... RACHEL | 18 Years - 75 Years | Voronezh N.N. Burdenko State Medical Academy | |
Computer Navigation-assisted Surgery for Locally Advanced and Recurrent Rectal Cancer | NCT04512937 | Rectal Cancer | Computer-assist... | 18 Years - | Oslo University Hospital | |
Functional Outcomes and Quality of Life in Patients Undergoing Surgery for Rectal Cancer | NCT00579579 | Rectal Cancer | Questionaires | 18 Years - | Memorial Sloan Kettering Cancer Center | |
Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer | NCT00068692 | Rectal Mucinous... Rectal Signet R... Recurrent Recta... Stage IIA Recta... Stage IIB Recta... Stage IIC Recta... Stage IIIA Rect... Stage IIIB Rect... Stage IIIC Rect... Stage IVA Recta... Stage IVB Recta... | Radiotherapy Fluorouracil Leucovorin Calc... Oxaliplatin Irinotecan | 18 Years - | National Cancer Institute (NCI) | |
FOLFOXIRI With or Without Intensification for Rectal Cancer | NCT03997435 | Rectal Cancer | Control arm Experimental ar... | 18 Years - | Chinese University of Hong Kong | |
Patient Activation Intervention in Improving Screening Rates for Colorectal Cancer | NCT01801059 | Colon Cancer Rectal Cancer | educational int... educational int... questionnaire a... | 50 Years - | Ohio State University Comprehensive Cancer Center | |
Randomized Controlled Study on Optimize Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer | NCT02031939 | Advanced Rectal... | Induction chemo... standard chemor... | 18 Years - 75 Years | Sun Yat-sen University | |
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy | NCT01113736 | Colon Cancer Rectal Cancer | AlloMEM™ | 18 Years - | University Hospitals Cleveland Medical Center | |
A Multicenter Single-arm P2 to Evaluate Safety and Efficacy of the Total Neoadjuvant Therapy for cT2 Rectal Cancer | NCT05939661 | Rectal Cancer | Radiation Chemotherapy Surgery | 18 Years - | Osaka University | |
PTC Drug Sensitivity Detection to Guide Postoperative Adjuvant of Colorectal Cancer | NCT05978349 | Colo-rectal Can... | adjuvant therap... | 18 Years - 75 Years | Peking Union Medical College Hospital | |
Online Adaptive Radiation Therapy for Rectal Cancer | NCT05911789 | Rectal Cancer | Online adaptive... | 18 Years - | Peking Union Medical College Hospital | |
A Prospective Feasibility Study for TAMIS | NCT02626728 | Rectal Cancer | laparoscopic as... | 18 Years - 99 Years | Hvidovre University Hospital | |
Capecitabine in the Perioperative Treatment of Rectal Cancer | NCT01500993 | Rectal Cancer | Capecitabine 5-FU | 18 Years - | Universitätsmedizin Mannheim | |
A Study of Bevacizumab (Avastin) in Participants With Newly Diagnosed Locally Advanced Rectal Cancer | NCT00865189 | Rectal Cancer | Bevacizumab Oxaliplatin Folinic Acid 5-fluorouracil Preoperative Ra... Surgery | 18 Years - 75 Years | Hoffmann-La Roche | |
High Dose Vitamin D Study | NCT01150877 | Colorectal Canc... | Vitamin D | 18 Years - | University of British Columbia | |
Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma | NCT02935309 | Rectal Cancer Rectal Adenocar... | Lenvatinib Capecitabine External Radiat... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
Percutaneous Tibial Nerve Stimulation in the Treatment of Anterior Resection Syndrome After Rectal Cancer Surgery | NCT02177084 | Rectal Cancer Low Anterior Re... | PTNS | 18 Years - 80 Years | IRCCS Azienda Ospedaliero-Universitaria di Bologna | |
Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients | NCT06043999 | Chemotherapy Ef... Rectal Cancer | Radical total m... Salavge Adjuvan... | 18 Years - 75 Years | Sun Yat-sen University |