Spots Global Cancer Trial Database for Predicting Neoadjuvant Therapy Response of Rectal Cancer With MRI
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Trial Identification
Brief Title: Predicting Neoadjuvant Therapy Response of Rectal Cancer With MRI
Official Title: Predicting Neoadjuvant Therapy Response of Rectal Cancer With MRI
Study ID: NCT02640586
Conditions
Interventions
Study Description
Brief Summary: The purpose of this study is to investigate if MRI scans performed after neoadjuvant radiotherapy can predict the therapeutic response of rectal cancer following preoperative chemo-radiotherapy. This will help doctors to better tailor treatments for rectal cancer in the future.
Detailed Description: We proposed to constructed multi-parameter predictive model for predicting therapeutic response and pathological complete response(pCR) of patients with rectal cancer who received neoadjuvant chemoradiation. MR radiomics,convolutional neural networks, morphological parameters and quantitative functional parameters derived from diffusion-weighted MR images will be integrated for model construction.
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Peking University Cancer Hospital, Beijing, Beijing, China
Beijing Chao Yang Hospital, Beijing, Beijing, China
Beijing Friendship Hospital Capital Medical University, Beijing, Beijing, China
Chinese Academy of Medical Sciences, Cancer Hospital & Institute, Beijing, Beijing, China
The First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China
Guangxi Cancer Hospital, Guilin, Guangxi, China
Hubei Cancer Hospital, Wuhan, Hubei, China
Hunan Cancer Hospital, Changsha, Hunan, China
Jilin Cancer Hospital, Changchun, Jilin, China
The First Affiliated Hospital of Jilin University, Changchun, Jilin, China
Shanxi Cancer Hospital, Taiyuan, Shanxi, China
Contact Details
Name: Ying-Shi Sun, MD
Affiliation: No.52 Fu Cheng Road, Hai Dian District, Beijing, 10142
Role: STUDY_CHAIR
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