Spots Global Cancer Trial Database for Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study)
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Trial Identification
Brief Title: Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis (REGAIN Study)
Official Title: A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Eculizumab in Subjects With Refractory Generalized Myasthenia Gravis (gMG)
Study ID: NCT01997229
Conditions
Study Description
Brief Summary: The purpose of this study is to determine if eculizumab is safe and effective for the treatment of refractory generalized Myasthenia Gravis.
Detailed Description:
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
University of Alabama, Birmingham, Alabama, United States
University of California San Francisco-Fresno, Fresno, California, United States
University of Southern California, Los Angeles, California, United States
University of California-Irvine, Orange, California, United States
University of California Davis Health System, Sacramento, California, United States
California Pacific Medical Center, San Francisco, California, United States
Stanford University School of Medicine, Stanford, California, United States
Yale New Haven Hospital, New Haven, Connecticut, United States
University of Florida Health Science Center, Jacksonville, Florida, United States
University of Miami School of Medicine, Miami, Florida, United States
University of South Florida, Tampa, Florida, United States
Georgia Regents University, Augusta, Georgia, United States
Medical Associates of North Georgia, Canton, Georgia, United States
Southern Illinois University School of Medicine, Springfield, Illinois, United States
Indiana University, Indianapolis, Indiana, United States
University of Iowa College of Medicine, Iowa City, Iowa, United States
University of Kansas Medical Center, Kansas City, Kansas, United States
University of Maryland Medical Center, Baltimore, Maryland, United States
Johns Hopkins University School Of Medicine, Baltimore, Maryland, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Brigham and Women's Hospital, Boston, Massachusetts, United States
Lahey Clinic Inc., Burlington, Massachusetts, United States
Wayne State University School of Medicine, Detroit, Michigan, United States
Las Vegas Clinic, Las Vegas, Nevada, United States
Buffalo General Hospital, Buffalo, New York, United States
Hospital For Special Surgery/New York Presbyterian Hospital Cornell Campus, New York, New York, United States
Mount Sinai School of Medicine, New York, New York, United States
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Carolinas Healthcare System, Charlotte, North Carolina, United States
Duke University Health System, Durham, North Carolina, United States
Ohio State University Medical Center, Columbus, Ohio, United States
Oregon Health & Science University, Portland, Oregon, United States
University of Pennsylvania, Philadelphia, Pennsylvania, United States
Rhode Island Hospital, Providence, Rhode Island, United States
Wesley Neurology Clinic, Cordova, Tennessee, United States
Vanderbilt Medical Center, Nashville, Tennessee, United States
UT Southwestern, Dallas, Texas, United States
Methodist Neurological Institute, Houston, Texas, United States
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States
University of Vermont Medical Center, Burlington, Vermont, United States
University of Washington, Seattle, Washington, United States
Hospital Italiano, Ciudad Autonoma, Buenos Aires, Argentina
Instituto de Investigaciones Neurologicas Raul Carrea, FLENI, Ciudad Autonoma, Buenos Aires, Argentina
St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia
Royal Perth Hospital, Perth, Western Australia, Australia
UZ Antwerpen, Edegem, , Belgium
AZ Sint-Lucas - Campus Sint-Lucas, Gent, , Belgium
UZ Leuven, Leuven, , Belgium
Hospital Mãe de Deus, Porto Alegre, Rio Grande Do Sul, Brazil
Faculdade de Medicina do ABC, Santo André, Sao Paulo, Brazil
Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, Sao Paulo, Brazil
HUCFF-UFRJ - Hospital Universitário Clementino Fraga Filho - Universidade Federal do Rio de Janeiro, Rio De Janeiro, , Brazil
UNIFESP - Universidade Federal de São Paulo, São Paulo, , Brazil
University of Alberta Hospital, Edmonton, Alberta, Canada
Toronto General Hospital, Toronto, Ontario, Canada
Montreal Neurological Institute, Montreal, Quebec, Canada
Vseobecna fakultni nemocnice v Praze, Praha, Prague, Czechia
Fakultni nemocnice Brno, Brno, , Czechia
Fakultni nemocnice Ostrava, Ostrava - Poruba, , Czechia
Århus Universitetshospital, Aarhus C, , Denmark
Rigshospitalet, København Ø, , Denmark
Helsingin yliopistollinen keskussairaala, Helsinki, , Finland
Neuro NEO Oy, Turku, , Finland
CHU de Nice Hôpital Pasteur 2, Nice Cedex 3, Alpes Maritimes, France
Groupe Hospitalier Pellegrin - Hôpital Pellegrin, Bordeaux Cedex, Gironde, France
Hopital Roger Salengro - CHU Lille, Lille Cedex, Nord, France
Hopital Neurologique Pierre Wertheimer, Bron cedex, Rhone, France
LMU-Campus Innenstadt, Muenchen, Bayern, Germany
Medizinische Hochschule Hannover, Hannover, Niedersachsen, Germany
Navy Hospital of Athens, Athens, , Greece
General Hospital of Thessaloniki "G. Papanikolaou", Thessaloniki, , Greece
Jahn Ferenc Del-Pesti Korhaz, Budapest, , Hungary
Szegedi Tud.Egyetem Szent-Gyorgyi Albert Klin. Közp., Szeged, , Hungary
Policlinico di Catania, Catania, , Italy
Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, , Italy
Azienda Ospedaliera Universitaria "Federico II", Napoli, , Italy
Ospedale San Camillo IRCCS, Padova, , Italy
Azienda Ospedaliero Universitaria Pisana, Pisa, , Italy
Umberto I Pol. di Roma-Università di Roma La Sapienza, Roma, , Italy
Policlinico Universitario Agostino Gemelli, Roma, , Italy
Azienda Ospedaliera Sant'Andrea - Università di Roma La Sapienza, Roma, , Italy
Ospedale Santa Chiara, Trento, , Italy
Chiba University Hospital, Chiba-shi, Chiba-Ken, Japan
Kyushu University Hospital, Fukuoka-shi, Fukuoka-Ken, Japan
Sapporo Medical University Hospital, Sapporo-shi, Hokkaido, Japan
Hanamaki General Hospitals, Hanamaki-shi, Iwate-Ken, Japan
NHO Sendai Medical Center, Sendai-shi, Miyagi-Ken, Japan
NHO Nagasaki Kawatana Medical Center, Kawatana, Nagasaki-Ken, Japan
Nagasaki University Hospital, Nagasaki-shi, Nagasaki-Ken, Japan
Kinki University Hospital, Osakasayama-shi, Osaka-Fu, Japan
Osaka University Hospital, Suita-shi, Osaka-Fu, Japan
Toho University Ohashi Medical Center, Meguro-ku, Tokyo-To, Japan
Yamaguchi University Hospital, Ube-shi, Yamaguchi-Ken, Japan
Severance Hospital, Yonsei University Health System, Seoul, , Korea, Republic of
Samsung Medical Center, Seoul, , Korea, Republic of
Korea University Anam Hospital, Seoul, , Korea, Republic of
Seoul Metropolitan Government Seoul National University, Seoul, , Korea, Republic of
Academisch Medisch Centrum, Amsterdam, , Netherlands
Leiden Universitair Medisch Centrum, Leiden, , Netherlands
Maastricht University Medical Center, Maastricht, , Netherlands
Hospital Universitari Vall d'Hebron, Barcelona, , Spain
Hospital de la Santa Creu i Sant Pau, Barcelona, , Spain
Hospital Universitari de Bellvitge, Barcelona, , Spain
Hospital Universitario La Paz, Madrid, , Spain
Sahlgrenska Sjukhuset, Göteborg, , Sweden
Karolinska Universitetssjukhuset - Solna, Stockholm, , Sweden
Hacettepe University Medical Faculty, Ankara, , Turkey
Karadeniz Tecnical Uni. Med. Fac., Istanbul, , Turkey
Dokuz Eylul University Medicine Faculty, Izmir, , Turkey
Kocaeli University Medical Faculty, Kocaeli, , Turkey
Ondokuz Mayıs University of Medicine, Samsun, , Turkey
The Walton Centre, Liverpool, Merseyside, United Kingdom
Queen Elizabeth Hospital, Birmingham, West Midlands, United Kingdom
King's College Hospital, London, , United Kingdom
Contact Details
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