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Brief Title: Safety and Preliminary Efficacy of BNA035 in Patients With Advanced Solid Tumors
Official Title: A Phase 1 Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of BNA035 in Patients With Advanced Solid Tumors
Study ID: NCT05150457
Brief Summary: The purpose of the study is to evaluate the safety and tolerability of BNA035 in order to determine the maximum tolerated dose (MTD) and Recommended Phase 2 dose (RP2D) and to evaluate the preliminary efficacy for each combination regimen.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
St George Private Hospital, Kogarah, New South Wales, Australia
Pindara Private Hospital, Benowa, Queensland, Australia
St. Vincents Hospital Melbourne, Fitzroy, Victoria, Australia
Name: Josh Xiao, PhD
Affiliation: Binacea Pharma, Inc.
Role: STUDY_CHAIR