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Spots Global Cancer Trial Database for Laparoscopic Partial Nephrectomy for cT1 Tumors

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Trial Identification

Brief Title: Laparoscopic Partial Nephrectomy for cT1 Tumors

Official Title: Evaluation Trifecta and Pentafecta Outcomes of Patients Underwent Laparoscopic Partial Nephrectomy for cT1 Renal Tumor

Study ID: NCT04213157

Interventions

Study Description

Brief Summary: The aim of the study is to evaluate trifecta and pentafecta outcomes for laparoscopic partial nephrectomy (LNP) in patients with clinical T1N0M0 renal tumor.

Detailed Description: From November 2009 to August 2018 a total of 292 patients who underwent LPN by global ischemia were included in the study. The patients were allocated into two groups according to the tumor size; T1a (≤ 40 mm, n=215), T1b (41-70 mm, n=77). Demographics features, clinical tumor characteristics, intraoperative and postoperative outcomes were analyzed. A negative surgical margin, warm ischemia time (WIT) \< 20 min and no postoperative complications (Clavien-Dindo ≥ grade 3) were accepted to achieve the trifecta outcomes. Pentafecta has defined as trifecta criteria plus \>90% preservation of estimated glomerular filtration rate (eGFR) and no stage upgrade of chronic kidney disease 12 months after LPN. Univariable and multivariable analysis were used to identify factors predicting trifecta and pentafecta achievement.

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Liv hospital samsun, Samsun, , Turkey

Ondokuz Mayıs University, Samsun, , Turkey

Contact Details

Name: Saban Sarıkaya, Professor

Affiliation: Ondokuz Mayıs University

Role: STUDY_CHAIR

Name: Ender Ozden, Professor

Affiliation: Ondokuz Mayıs University

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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