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Brief Title: Study of Sunitinib in Subjects With High Risk Renal Cell Carcinoma
Official Title: Phase II, Open Label, Single Center Study of Sunitinib in Subjects With High Risk Renal Cell Carcinoma
Study ID: NCT01070186
Brief Summary: This study is designed to explore the molecular modulatory effect of Sunitinib when given in a neoadjuvant setting prior to radical or partial nephrectomy. The study will evaluate aforementioned outcomes in 30 patients at a dose of 50mg/day for 4 weeks followed by surgery 2-4 weeks following the last dose.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Name: Fairooz Kabbinavar, M.D.
Affiliation: University of California, Los Angeles
Role: PRINCIPAL_INVESTIGATOR