Spots Global Cancer Trial Database for Immune Biomarker Study for Salivary Gland Carcinoma
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Trial Identification
Brief Title: Immune Biomarker Study for Salivary Gland Carcinoma
Official Title: Immune Biomarker Study for Salivary Gland Carcinoma
Study ID: NCT06047236
Interventions
Study Description
Brief Summary: Aims of this study are analyses of tumor metabolome, tumor transcriptome and tumor proteome as well as of the immune infiltration, separated by histological entity. These data will subsequently be compared with the with the detailed immune status determined in the patient's peripheral blood and saliva using machine learning techniques, among others, to create a biomarker cluster for salivary gland tumors. These can be used in clinical routine. In addition, the investigators would like to study a subset of patients from freshly resected tumor organoids from freshly resected tumor tissue according to already established methods in order to mechanistic investigations of prognostic parameters.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Universitätsklinikum Erlangen, HNO, Erlangen, Bavaria, Germany
Universitätsklinikum Erlangen, Strahlenklinik, Erlangen, Bavaria, Germany
Contact Details
Name: Sarina Mueller, PD
Affiliation: Universitätsklinikum Erlangen, HNO
Role: STUDY_DIRECTOR
Name: Marlen Haderlein, PD
Affiliation: Universitätsklinikum Erlangen, Radiation Oncology
Role: STUDY_DIRECTOR
Name: Benjamin Frey, PD
Affiliation: Universitätsklinikum Erlangen, Radiation Oncology, Translational Radiobiology
Role: PRINCIPAL_INVESTIGATOR
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