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Spots Global Cancer Trial Database for Safety Study of a Fluorescent Marker to Visualize Cancer Cells

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Trial Identification

Brief Title: Safety Study of a Fluorescent Marker to Visualize Cancer Cells

Official Title: A Phase 1 Dose Escalation/Expansion Study of BLZ-100 Administered by Intravenous Injection in Adult Subjects With Skin Cancer

Study ID: NCT02097875

Conditions

Skin Neoplasms

Interventions

BLZ-100

Study Description

Brief Summary: Many types of cancer are primarily treated with surgery and patient survival is directly related to the extent to which the tumor is able to be removed. It is often difficult for surgeons to distinguish tumor tissue from normal tissue or to detect tumor cells that have spread from the original tumor site, resulting in incomplete removal of the tumor and reduced patient survival. In addition, in some sites, such as the brain, it is critical to avoid damage to normal tissue around the tumor to prevent adverse effects of surgery on function. We hypothesize that BLZ-100 will improve surgical outcomes by allowing surgeons to visualize the edges of the tumor and small groups of cancer cells that have spread to other sites in real-time, as they operate.

Detailed Description:

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

Veracity Clinical Research Pty Ltd, Woolloongabba, Queensland, Australia

Contact Details

Name: Lynda Spelman, MBBS FACD

Affiliation: Veracity Clinical Research Pty Ltd

Role: PRINCIPAL_INVESTIGATOR

Useful links and downloads for this trial

Clinicaltrials.gov

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