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Spots Global Cancer Trial Database for Screening to Improve Survival in AL Amyloidosis

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Trial Identification

Brief Title: Screening to Improve Survival in AL Amyloidosis

Official Title: Screening to Improve Survival in AL Amyloidosis

Study ID: NCT04615572

Interventions

Study Description

Brief Summary: The purpose of this study is to see whether certain genes may be linked with the development of AL amyloidosis in subjects 60 years of age or older with the blood disorders SMM and MGUS. A limited repertoire of immunoglobulin (Ig) variable region genes have been associated with AL amyloidosis. The clonal plasma cells of subjects with SMM and MGUS may express one of these Ig variable region genes indicating a risk of progression to AL amyloidosis and potentially enabling early diagnosis. We hope this study will help us begin to understand whether Ig variable region gene identification can be a useful tool for assessing a subject's risk of progression to AL amyloidosis.

Detailed Description:

Eligibility

Minimum Age: 60 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

University of California, Irvine Health Chao Family Comprehensive Cancer Center, Orange, California, United States

University of California, San Francisco, San Francisco, California, United States

University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States

Tufts Medical Center, Boston, Massachusetts, United States

Columbia University Irving Medical Center, New York, New York, United States

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States

Contact Details

Useful links and downloads for this trial

Clinicaltrials.gov

Google Search Results

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