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Brief Title: Evaluation of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer
Official Title: Randomized Phase III Trial Evaluating the Impact of Hysterectomy After Chemoradiation Therapy for Stage IB2/II Cervical Cancer
Study ID: NCT01363466
Brief Summary: GYNECO 02 hypothesis is that hysterectomy reduces the possibility of local or loco-regional relapse, especially in patient with a reduced metastatic risk and who received a local chemoradiation therapy with an increase of radiotherapy doses (45 grays).
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: FEMALE
Healthy Volunteers: No
Clinique Axium, Aix-en-Provence, , France
Polyclinique du Parc Rambot, Aix-en-Provence, , France
Clinique Sainte Thérèse de l'enfant Jésus, Amiens, , France
Centre Hospitalier Universitaire, Amiens, , France
Centre Paul Papin, Angers, , France
Centre Hospitalier de Beauvais, Beauvais, , France
Institut Bergonié, Bordeaux, , France
Centre Hospitalier Nord Deux-Sèvres, Bressuire Cedex, , France
Centre Hospitalier Universitaire de Brest, Brest, , France
Centre Hospitalier Intercommunal, Créteil, , France
Centre Georges-François Leclerc, Dijon, , France
Centre Hospitalier de Fontainebleau, Fontainebleau, , France
Hôpital Hotel-Dieu, Lyon Cedex 02, , France
Centre Hospitalier Edouard Herriot, Lyon, , France
Centre Hospitalier Lyon Sud, Lyon, , France
Institut paoli Calmettes, Marseille Cedex 09, , France
Hôpital de la conception, Marseille cedex 5, , France
Centre Hospitalier Régional Universitaire La Timone, Marseille, , France
Centre Hospitalier Régional Universitaire Hôpital Nord, Marseille, , France
Centre Hospitalier Universitaire - Hôpital Arnaud de Villeneuve, Montpellier, , France
Centre Val d'Aurelle-Paul Lamarque, Montpellier, , France
Centre hospitalier des Pays de Morlaix, Morlaix, , France
Centre René Gauducheau, Nantes, , France
Hôpital de la Source, Orléans, , France
Hôpital des Diaconnesses, Paris Cedex 12, , France
Hôpital Européen Georges Pompidou, Paris Cedex 15, , France
Centre Hospitalier Universitaire Jean Bernard, Poitiers Cedex, , France
Polyclinique de Courlancy, Reims, , France
Clinique Mutualiste de la Sagesse, Rennes Cedex, , France
Centre Universitaire Hospitalier- Hôpital Sud, Rennes, , France
Centre Henri Becquerel, Rouen, , France
Centre René Huguenin, Saint-Cloud, , France
Institut Claudius Régaud, Toulouse Cedex, , France
Centre Hospitalier Bretonneau, Tours, , France
Institut Gustave Roussy, Villejuif, , France
Name: Philippe MORICE, Pr
Affiliation: Gustave Roussy, Cancer Campus, Grand Paris
Role: PRINCIPAL_INVESTIGATOR