Spots Global Cancer Trial Database for Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases

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Trial Identification

Brief Title: Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases

Official Title: Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases

Study ID: NCT02181829

Conditions

Synovial Sarcoma

Single or Multiple Lung Metastases

Interventions

Whole Lung IMRT

Study Description

Brief Summary: The purpose of this study is to find out what effects, good and/or bad, radiation has on the lungs has on the patient and on synovial sarcoma which has spread to the lungs. The standard treatment for synovial sarcoma which has spread to the lungs is chemotherapy with or without surgery to remove the tumors in the lungs. However, tumors often come back in the lungs after chemotherapy and/or surgery. Since synovial sarcoma is known to be sensitive to radiation, this study is looking at whether radiation therapy which is targeted to the entire lung can further reduce the chances of the cancer returning. This type of radiation is commonly used in other types of sarcoma to treat the cancer once it has spread to the lungs and it may be very useful in synovial sarcoma as well. In this study, a special type of radiation will be used, called Intensity Modulated Radiation Therapy (IMRT). With IMRT the radiation beams are more customized to focus more radiation on the tumor cells while delivering less radiation to areas like the heart. The goal of this study is also to measure pulmonary toxicity and see if IMRT is feasible and has less toxicity.

Detailed Description: