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Brief Title: Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM)
Official Title: Single-arm, Multicentre, Phase II Study of Immunotherapy in Patients With Type B3 Thymoma and Thymic Carcinoma Previously Treated With Chemotherapy
Study ID: NCT03134118
Brief Summary: The aim of the phase II Nivothym study is to collect data on activity and toxicity of nivolumab therapy in patients with thymic carcinoma or type B3 thymoma that previously received a first platinum-based chemotherapy.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Institut Jules Bordet, Brussel, , Belgium
Universitair Ziekenhuis Antwerpen (UZA), Edegem, , Belgium
CHU de Brest, Brest, , France
CHU de Lyon - Hopital Louis Pradel, Bron, , France
Centre Francois Baclesse, Caen, , France
CHU de Grenoble - La Tronche - Hôpital A. Michallon, La Tronche, , France
Assistance Publique - Hopitaux de Marseille - Hopital Nord (APHM), Marseille, , France
Institut Curie- Hopital de Paris, Paris, , France
CHU Toulouse - Hopital Larrey, Toulouse, , France
Gustave Roussy, Villejuif, , France
The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis, Amsterdam, , Netherlands
Academisch Ziekenhuis Maastricht, Maastricht, , Netherlands
Erasmus MC, Rotterdam, , Netherlands
Vall d'Hebron Institut d'Oncologia, Barcelona, , Spain
Hospital Universitario 12 De Octubre, Madrid, , Spain
UniversitaetsSpital Zurich, Zurich, , Switzerland
NHS Greater Glasgow and Clyde - Beatson West of Scotland Cancer Centre - Gartnavel General Hospital, Glasgow, , United Kingdom
Royal Marsden Hospital - Chelsea, London, London, , United Kingdom
Royal Marsden Hospital - Sutton, Surrey, Sutton, , United Kingdom
The Christie NHS Foundation Trust, Wythenshawe, , United Kingdom
Name: Nicolas Girard
Affiliation: Institut Curie, Paris, France
Role: PRINCIPAL_INVESTIGATOR
Name: Solange Peters
Affiliation: University of Lausanne Hospitals
Role: PRINCIPAL_INVESTIGATOR