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Brief Title: Effect of Carum Carvi on Thyroid Hormones and TSH Level
Official Title: Evaluation of the Effect of Carum Carvi on Levels of Plasma Thyroid Hormones and TSH Level in Patients on Thyroid Hormone Therapy and Normal Controls.
Study ID: NCT01471288
Brief Summary: Carum Carvi has been frequently used in traditional medicine for a variety of disease ranging from dyspepsia to Alzheimer's disease.We observed high TSH levels in few patients with thyroid cancer who receiving Carum Carvi despite being on suppressive dose of levothyroxin. TSH level returned to normal after discontinuation of the Carum carvi. This observation led to a pilot study for evaluation of the effect of carum carvi on thyroid function.
Detailed Description:
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: Yes
Nuclear Medicine Department, Ghaem Hospital, Mashhad, , Iran, Islamic Republic of
Name: Seyed Rasoul Zakavi, MD. IBNM
Affiliation: Nuclear Medicine Research Center
Role: PRINCIPAL_INVESTIGATOR
Name: Mohammad Ramezani, Ph.D., Pharm.D
Affiliation: Pharmaceutical Research Center
Role: PRINCIPAL_INVESTIGATOR