Spots Global Cancer Trial Database for Intravenous Tranexamic Acid Reducing Intraoperative Blood Loss in Huge Meningiomas Resection
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Trial Identification
Brief Title: Intravenous Tranexamic Acid Reducing Intraoperative Blood Loss in Huge Meningiomas Resection
Official Title: Effect of Tranexamic Acid on Intraoperative Blood Loss in Patients Undergoing Brain Meningioma Resections: Study Protocol of a Randomised Controlled Trial
Study ID: NCT05230381
Study Description
Brief Summary: Intra-operative blood loss of huge meningioma resection patients on average was over 1000ml. Intra-operative massive hemorrhage was associated with longer hospital of stay, higher expense, and higher mortality. Previous studies indicated intra-operative tranexamic acid infusion would decrease blood loss for cardiac, trauma and obstetric procedures. However, limited researches focusing on the effect of tranexamic acid in neurosurgery population, with heterogenous pathologies. The purpose of this study was to investigate the effect of tranexamic acid on intra-operative blood loss in patients undergoing huge meningioma resection.
Detailed Description:
Keywords
Eligibility
Minimum Age: 18 Years
Eligible Ages: ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Beijing Tiantan Hospital, Capital Medical University, Beijing, Beijing, China
Contact Details
Name: Shu Li, M.D.
Affiliation: Beijing Tiantan Hospital
Role: PRINCIPAL_INVESTIGATOR
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