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Spots Global Cancer Trial Database for Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma

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Trial Identification

Brief Title: Study Evaluating Single and Repeated Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma

Official Title: A Phase 1, Open-label, Multicenter Study Evaluating the Safety and Tolerability, Biologic Activity, Pharmacodynamics, and Pharmacokinetics of Single and Repeated Escalating Intravitreal Doses of ICON-1 in Patients With Uveal Melanoma Who Are Planned to Undergo Enucleation or Brachytherapy

Study ID: NCT02771340

Interventions

ICON-1

Study Description

Brief Summary: The purpose of this study is to evaluate the safety, tolerability, biological activity, pharmacokinetics and pharmacodynamic activity of single and repeated escalating intravitreal doses of ICON-1 in patients with primary uveal melanoma who are planned to undergo enucleation or brachytherapy of the affected eye.

Detailed Description:

Keywords

Eligibility

Minimum Age: 18 Years

Eligible Ages: ADULT, OLDER_ADULT

Sex: ALL

Healthy Volunteers: No

Locations

, San Francisco, California, United States

, Denver, Colorado, United States

, Leawood, Kansas, United States

, Boston, Massachusetts, United States

, Grand Rapids, Michigan, United States

, Royal Oak, Michigan, United States

, Portland, Oregon, United States

, Philadelphia, Pennsylvania, United States

Contact Details

Name: Gabriela Burian, MD

Affiliation: Iconic Therapeutics, Inc.

Role: STUDY_DIRECTOR

Useful links and downloads for this trial

Clinicaltrials.gov

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