Spots Global Cancer Trial Database for Biomarkers in Samples From Younger Patients With Wilms Tumor
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Trial Identification
Brief Title: Biomarkers in Samples From Younger Patients With Wilms Tumor
Official Title: Observational - Relationships Between Tumor-Associated Macrophages and Clinicopathological Factors in Wilms Tumor
Study ID: NCT01493817
Interventions
Study Description
Brief Summary: This research study is studying biomarkers in tissue samples from younger patients with Wilms tumor. Studying samples of tissue from patients with cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer. It may also help doctors predict how patients respond to treatment
Detailed Description: PRIMARY OBJECTIVES: I. To determine whether recruitment of tumor-associated macrophages is related to clinicopathological factors in Wilms tumor (tumor stage, presence of vascular invasion, tumor progression, and survival). OUTLINE: Paraffin-embedded specimens are analyzed for macrophage markers. Results of each sample are then compared with patient's tumor stage, presence of vascular invasion, tumor progression, and survival.
Keywords
Eligibility
Minimum Age:
Eligible Ages: CHILD, ADULT, OLDER_ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Children's Oncology Group, Monrovia, California, United States
Contact Details
Name: Jessica Kandel, MD
Affiliation: Children's Oncology Group
Role: PRINCIPAL_INVESTIGATOR
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