Spots Global Cancer Trial Database for Effect of Childhood Radioiodine Therapy on Salivary Function
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Trial Identification
Brief Title: Effect of Childhood Radioiodine Therapy on Salivary Function
Official Title: Effect of Childhood Radioiodine Therapy on Salivary Function
Study ID: NCT02375451
Interventions
Study Description
Brief Summary: Radioiodine (I-131) therapy for thyroid disease is known to decrease salivary function in adult patients. The impact of pediatric I-131 exposure on salivary function is unknown. The investigators goals are to answer this question by measuring salivary gland function before and after I-131 administration in children who receive radioiodine therapy at our hospital for thyroid disease.
Detailed Description: Radioiodine (I-131) therapy for thyroid disease is known to decrease salivary function in adult patients. The impact of pediatric I-131 exposure on salivary function is unknown. The investigators goals are to answer this question by measuring salivary gland function before and after I-131 administration in children who receive radioiodine therapy at our hospital for thyroid disease. We will use a Modified Shirmer Test to measure saliva production and a questionnaire to evaluation symptoms of xerostomia.
Keywords
Eligibility
Minimum Age: 3 Years
Eligible Ages: CHILD, ADULT
Sex: ALL
Healthy Volunteers: No
Locations
Boston Children's Hospital, Boston, Massachusetts, United States
Contact Details
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