Spots Global Cancer Trial Database for xerostomia
Every month we try and update this database with for xerostomia cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Blinded Dry Mouth Spray Crossover Study | NCT04608773 | Xerostomia Head and Neck C... Xerostomia Foll... | Remineralizing ... Alcohol-Free Mo... | 18 Years - | University of Pittsburgh | |
| The Efficacy of Hibiscus Sabdariffa in Xerostomia | NCT06413550 | Radiation-induc... | Hibiscus Sabdar... | 20 Years - 70 Years | Ain Shams University | |
| An Investigation Into Taste Problems Associated With Xerostomia in Patients With Advanced Cancer | NCT06287294 | Taste, Altered Xerostomia Neoplasms | 18 Years - | Our Lady's Hospice and Care Services | ||
| The Efficacy of Hibiscus Sabdariffa in Xerostomia | NCT06413550 | Radiation-induc... | Hibiscus Sabdar... | 20 Years - 70 Years | Ain Shams University | |
| Acupuncture-Like Transcutaneous Electrical Nerve Stimulation in Treating Radiation-Induced Xerostomia in Patients With Head and Neck Cancer | NCT02474095 | Head and Neck C... Xerostomia | Quality-of-Life... Transcutaneous ... | 18 Years - | Roswell Park Cancer Institute | |
| Electroacupuncture in Treating Chronic Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer | NCT00623129 | Head and Neck C... Radiation Toxic... Xerostomia | questionnaire a... electroacupunct... management of t... quality-of-life... | 21 Years - 89 Years | Mayo Clinic | |
| Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer | NCT00068237 | Head and Neck C... Radiation Toxic... Xerostomia | salivary gland ... Post-operative ... | 18 Years - | Radiation Therapy Oncology Group | |
| d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT04392622 | Xerostomia | D-Limonene Gelc... Intensity modul... Cisplatin Xerostomia ques... | 18 Years - | Stanford University | |
| d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma | NCT04392622 | Xerostomia | D-Limonene Gelc... Intensity modul... Cisplatin Xerostomia ques... | 18 Years - | Stanford University | |
| Neurological Effects of Acupuncture to Prevent Radiation-induced Xerostomia | NCT02292368 | Head and Neck C... | Questionnaires Acupuncture Electroencephal... | 18 Years - | M.D. Anderson Cancer Center | |
| Oral Health and Oral Health-Related Quality of Life in Early Stage Breast Cancer Survivors | NCT01272570 | Breast Cancer Xerostomia | 50 Years - | University of Michigan | ||
| Nutritional Status and Barriers to Dietary Intake in Head and Neck Cancer Patients | NCT00375180 | Head and Neck C... | 18 Years - | AHS Cancer Control Alberta | ||
| Combination Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Head and Neck Cancer | NCT00352118 | Head and Neck C... | filgrastim pegfilgrastim cisplatin docetaxel fluorouracil conventional su... radiation thera... | 18 Years - | Masonic Cancer Center, University of Minnesota | |
| Sparing Parotid Ducts Via MRI Sialography for Reduced Patient Reported Xerostomia | NCT06276946 | Oropharynx Canc... Head and Neck C... Xerostomia | standard radiot... experimental ra... | 18 Years - | UNC Lineberger Comprehensive Cancer Center | |
| Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer | NCT00372320 | Parotid Salivar... | Gene Transfer AdhAQP1 | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Effect of AdhAQP1 on Salivary Flow in Patients Treated With Radiation for Head and Neck Cancer | NCT00372320 | Parotid Salivar... | Gene Transfer AdhAQP1 | 18 Years - | National Institutes of Health Clinical Center (CC) | |
| Effectiveness of Thyme Honey in Management of Xerostomia in Post Radiation Cancer Patients | NCT05859711 | Head and Neck C... | thyme honey mou... saline mouth ri... | 25 Years - 65 Years | Ain Shams University | |
| Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia | NCT02854358 | Xerostomia Head and Neck C... | mixed powder of... Hypozalix spray... | 20 Years - 70 Years | Shiraz University of Medical Sciences | |
| Frequency of Xerostomia and Their Management in Upper Aerodigestive Tract Cancer Patients After the End of Radiotherapy | NCT02857413 | Head and Neck N... | - | Centre Hospitalier Universitaire de Besancon | ||
| Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer | NCT00656513 | Head and Neck C... Xerostomia | Pilocarpine ALTENS | 18 Years - | Radiation Therapy Oncology Group | |
| The Use of Candy and Honey in Decreasing Salivary Gland Damage Following Radioiodine Therapy for Thyroid Cancer | NCT01833650 | Thyroid Cancer | thymus honey mo... | - | Cyprus University of Technology | |
| SDF Application in Oral Cancer Patients to Prevent Dental Caries | NCT05403125 | Dental Caries | silver diamine ... Sodium fluoride... | 18 Years - | Texas A & M University Baylor College Of Dentistry | |
| Frequency of Xerostomia and Their Management in Upper Aerodigestive Tract Cancer Patients After the End of Radiotherapy | NCT02857413 | Head and Neck N... | - | Centre Hospitalier Universitaire de Besancon | ||
| Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia | NCT00081029 | Head and Neck C... Radiation Toxic... Xerostomia | management of t... radiation thera... | - | National Cancer Institute (NCI) | |
| Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSCT | NCT05759975 | Oral Mucositis Hematopoietic N... Xerostomia Hyposalivation | Photobiomodulat... Photobiomodulat... | 18 Years - 90 Years | Federal University of Rio Grande do Sul | |
| Xerostomia Pilot Fudan: Acupuncture for Prevention of Radiation-Induced Xerostomia | NCT00862550 | Head and Neck C... Xerostomia | Acupuncture | 18 Years - | M.D. Anderson Cancer Center | |
| Xerostomia Pilot Fudan: Acupuncture for Prevention of Radiation-Induced Xerostomia | NCT00862550 | Head and Neck C... Xerostomia | Acupuncture | 18 Years - | M.D. Anderson Cancer Center | |
| Oral Health and Oral Health-Related Quality of Life in Early Stage Breast Cancer Survivors | NCT01272570 | Breast Cancer Xerostomia | 50 Years - | University of Michigan | ||
| A Trial of Concurrent Radiation Therapy, Cisplatin, and BMX-001 in Locally Advanced Head and Neck Cancer | NCT02990468 | Head and Neck C... | BMX-001 Radiation Thera... Cisplatin | 18 Years - | BioMimetix JV, LLC | |
| Evaluation of Treatment Related Toxicity After Radiotherapy for Head and Neck Cancer | NCT01621048 | Head and Neck N... Xerostomia Deglutition Dis... | 18 Years - | Universitaire Ziekenhuizen KU Leuven | ||
| Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients | NCT00408759 | Xerostomia | hypnosis | 18 Years - | Bnai Zion Medical Center | |
| Parotid-Sparing Intensity-Modulated Radiation Therapy Compared With Conventional Radiation Therapy in Treating Patients With Oropharyngeal or Hypopharyngeal Cancer Who Are at High Risk of Radiation-Induced Xerostomia | NCT00081029 | Head and Neck C... Radiation Toxic... Xerostomia | management of t... radiation thera... | - | National Cancer Institute (NCI) | |
| Margin-Based Vs. Robust Photon Radiotherapy Planning in IMRT of HN-SQCC | NCT03552965 | Squamous Cell C... | Robust Radiothe... Margin-Based Ra... | 21 Years - | University of Arkansas | |
| Ultrasound Evaluation of Tongue Movements in Speech and Swallowing | NCT00001167 | Otorhinolaryngo... Otorhinolaryngo... Pharyngeal Neop... Polymyositis Speech Disorder | - | National Institutes of Health Clinical Center (CC) | ||
| Selenomethionine in Reducing Mucositis in Patients With Locally Advanced Head and Neck Cancer Who Are Receiving Cisplatin and Radiation Therapy | NCT01682031 | Chemotherapeuti... Mucositis Radiation Toxic... Stage III Squam... Stage III Squam... Stage III Squam... Stage III Squam... Stage III Squam... Stage III Squam... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Stage IV Squamo... Xerostomia | selenomethionin... placebo cisplatin radiation thera... quality-of-life... | 18 Years - | Roswell Park Cancer Institute | |
| Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients | NCT00168181 | Cancer Head and Neck C... | Submandibular g... Salagen | 18 Years - | AHS Cancer Control Alberta | |
| Hypnosis for Treating Xerostomia Following Radiotherapy in Head & Neck Cancer Patients | NCT00408759 | Xerostomia | hypnosis | 18 Years - | Bnai Zion Medical Center | |
| Everolimus in Restoring Salivary Gland Function in Participants With Locally Advanced Head and Neck Cancer Treated With Radiation Therapy | NCT03578432 | Salivary Gland ... Xerostomia Head and Neck C... | Everolimus Laboratory Biom... Survey Administ... | 18 Years - 75 Years | University of Arizona | |
| Effects of Mucoprotective Product on Xerostomia | NCT01316393 | Xerostomia | XER2020 | 18 Years - 90 Years | Camurus AB | |
| Study Transplanting Bone Marrow Cells Into Salivary Glands to Treat Dry Mouth Caused by Radiation Therapy | NCT05820711 | Head and Neck C... Xerostomia | MSC | 18 Years - 90 Years | University of Wisconsin, Madison | |
| Effects of Mucoprotective Product on Xerostomia | NCT01316393 | Xerostomia | XER2020 | 18 Years - 90 Years | Camurus AB | |
| Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer | NCT03601962 | Xerostomia Asialia Hyposalivation Mouth Dryness | Aqualief Placebo | 18 Years - | Helsinn Healthcare SA | |
| Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia | NCT04007081 | Xerostomia Head and Neck C... | Bone Marrow Asp... Ultrasound Imag... Salivary Assay Quality of Life... | 18 Years - 89 Years | University of Wisconsin, Madison | |
| Effect of Childhood Radioiodine Therapy on Salivary Function | NCT02375451 | Xerostomia Hyperthyroidism Thyroid Cancer | Radioiodine | 3 Years - 55 Years | Boston Children's Hospital | |
| Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients | NCT00168181 | Cancer Head and Neck C... | Submandibular g... Salagen | 18 Years - | AHS Cancer Control Alberta | |
| Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia | NCT00503776 | Dysphagia Head and Neck C... Mucositis Xerostomia | exercise interv... amifostine trih... therapeutic die... | 21 Years - | Vanderbilt-Ingram Cancer Center | |
| Acupuncture-Like Transcutaneous Electrical Nerve Stimulation in Treating Radiation-Induced Xerostomia in Patients With Head and Neck Cancer | NCT02474095 | Head and Neck C... Xerostomia | Quality-of-Life... Transcutaneous ... | 18 Years - | Roswell Park Cancer Institute | |
| Can Cytokines Predict the Severity of Acute Mucositis and the Need for Gastrostomy Tubes (PEG)? | NCT00431925 | Oral Mucositis Xerostomia Weight Loss Head and Neck C... | 18 Years - 85 Years | Hadassah Medical Organization | ||
| Interest of Auriculotherapy in the Treatment of Xerostomia | NCT04222478 | Xerostomia | Specific auricu... Non-specific au... | 18 Years - | Hopital Foch | |
| Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia | NCT04007081 | Xerostomia Head and Neck C... | Bone Marrow Asp... Ultrasound Imag... Salivary Assay Quality of Life... | 18 Years - 89 Years | University of Wisconsin, Madison | |
| Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer | NCT00101582 | Mucositis Solid Tumors Stomatitis Head and Neck C... Squamous Cell C... | Placebo palifermin cisplatin chemo... Radiotherapy | 18 Years - | Swedish Orphan Biovitrum | |
| Neurological Effects of Acupuncture to Prevent Radiation-induced Xerostomia | NCT02292368 | Head and Neck C... | Questionnaires Acupuncture Electroencephal... | 18 Years - | M.D. Anderson Cancer Center | |
| Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction | NCT02446249 | Squamous Cell H... Radiation Induc... Salivary Hypofu... | AAV2hAQP1 | 18 Years - | MeiraGTx UK II Ltd | |
| Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC | NCT06122636 | Quality of Life Oral Mucositis Dental Plaque Periodontal Dis... Xerostomia Dysbiosis | The probiotic t... Placebo | 18 Years - | University of Barcelona | |
| Effect of Low Level Laser Therapy on Prevention of Radiotherapy Induced Xerostomia in Cancer Patients. | NCT04700475 | Head and Neck C... | low level laser citric acid sol... | 25 Years - 55 Years | Cairo University | |
| A New Oral salIvary equivAlent Compared to Two moisturizinG Mouth sprAys in Patients With xeRostomiA: NIAGARA Study | NCT02049112 | Xerostomia Hyposalivation Head and Neck C... Sjögren Syndrom... | Salivary equiva... Aequasyal Biotene | 18 Years - | Unither Pharmaceuticals, France | |
| Photobiomodulation Therapy in Patients With Head and Neck Cancer Post-Radiotherapy | NCT05614843 | Head and Neck C... Head and Neck N... Xerostomia | Energy density ... Sham placebo | 18 Years - 70 Years | Universidad de Granada | |
| Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study | NCT05106608 | Head and Neck C... Head and Neck N... Xerostomia | Energy density ... Energy density ... Sham placebo | 18 Years - | Universidad de Granada | |
| Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia | NCT04007081 | Xerostomia Head and Neck C... | Bone Marrow Asp... Ultrasound Imag... Salivary Assay Quality of Life... | 18 Years - 89 Years | University of Wisconsin, Madison | |
| The Use of Chewing Gum for Xerostomia and Hyposalivation After Radiotherapy for Oral and Oropharyngeal Tumors | NCT03302676 | Head and Neck C... Radiation Thera... Xerostomia Hyposalivation | Chewing gum | 18 Years - | Odense University Hospital | |
| Randomized Amifostine For SCCHN | NCT00095927 | Chemotherapeuti... Head and Neck C... Mucositis Radiation Toxic... Xerostomia | Amifostine Carboplatin Paclitaxel radiation | 18 Years - | Dana-Farber Cancer Institute | |
| Effectiveness of Photobiomodulation Protocols in Radiation-induced Oral Side Effects in H&N Cancer Patients | NCT05242991 | Mucositis Xerostomia Hyposalivation | Photobiomodulat... | 18 Years - 90 Years | Federal University of Rio Grande do Sul | |
| Mesenchymal Stemcells for Radiation Induced Xerostomia | NCT02513238 | Xerostomia | Mesenchymal ste... Isotonic NaCl | 18 Years - | Rigshospitalet, Denmark | |
| Acupuncture-Like Transcutaneous Electrical Nerve Stimulation (ALTENS) or Pilocarpine in Treating Early Dry Mouth in Patients Undergoing Radiation Therapy for Head and Neck Cancer | NCT00656513 | Head and Neck C... Xerostomia | Pilocarpine ALTENS | 18 Years - | Radiation Therapy Oncology Group | |
| A Trial Looking at Treating Dry Mouth After Radiotherapy for Head and Neck Cancer | NCT02941276 | Xerostomia Head and Neck N... | Active Electros... Sham Electrosti... | 18 Years - | University College, London | |
| Does Craniosacraltherapy Have an Effect on Xerostomia and Other Late Sequelae on People Who Has Been Suffering From Cancer in Mouth and Throat? | NCT05882890 | Xerostomia Foll... Xerostomia Foll... | cranio sacral t... | 18 Years - 81 Years | Rahbek Kraniosakralterapi | |
| Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSCT | NCT05759975 | Oral Mucositis Hematopoietic N... Xerostomia Hyposalivation | Photobiomodulat... Photobiomodulat... | 18 Years - 90 Years | Federal University of Rio Grande do Sul | |
| Can Cytokines Predict the Severity of Acute Mucositis and the Need for Gastrostomy Tubes (PEG)? | NCT00431925 | Oral Mucositis Xerostomia Weight Loss Head and Neck C... | 18 Years - 85 Years | Hadassah Medical Organization | ||
| Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction | NCT02446249 | Squamous Cell H... Radiation Induc... Salivary Hypofu... | AAV2hAQP1 | 18 Years - | MeiraGTx UK II Ltd | |
| Mouth Care Regimes During Radiotherapy | NCT00138827 | Head and Neck N... | Biotene (mouth ... | 18 Years - | St George Hospital, Australia | |
| Efficacy of a Probiotic and Microbiological Analysis on Oral Complications Induced by Antineoplastic Therapies in Patients With HNC | NCT06122636 | Quality of Life Oral Mucositis Dental Plaque Periodontal Dis... Xerostomia Dysbiosis | The probiotic t... Placebo | 18 Years - | University of Barcelona | |
| Mesenchymal Stemcells for Radiation Induced Xerostomia | NCT02513238 | Xerostomia | Mesenchymal ste... Isotonic NaCl | 18 Years - | Rigshospitalet, Denmark | |
| Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer | NCT03601962 | Xerostomia Asialia Hyposalivation Mouth Dryness | Aqualief Placebo | 18 Years - | Helsinn Healthcare SA | |
| Electroacupuncture in Treating Chronic Dry Mouth Caused By Radiation Therapy in Patients With Head and Neck Cancer | NCT00623129 | Head and Neck C... Radiation Toxic... Xerostomia | questionnaire a... electroacupunct... management of t... quality-of-life... | 21 Years - 89 Years | Mayo Clinic | |
| Acute and Longlasting Side Effects Caused by Radiotherapy in the Head and Neck Area | NCT00995319 | Head and Neck C... | 18 Years - | Norwegian University of Science and Technology | ||
| Structure and Functional Status of Parotid Glands Exposed to Therapeutic Irradiation | NCT00001523 | Radiation Injur... Xerostomia | - | National Institutes of Health Clinical Center (CC) | ||
| Nutritional Status and Barriers to Dietary Intake in Head and Neck Cancer Patients | NCT00375180 | Head and Neck C... | 18 Years - | AHS Cancer Control Alberta | ||
| Efficacy of Traditional Persian Medicine Preparation Versus Artificial Saliva for Radiation Induced Xerostomia | NCT02854358 | Xerostomia Head and Neck C... | mixed powder of... Hypozalix spray... | 20 Years - 70 Years | Shiraz University of Medical Sciences | |
| Effectiveness of Extraoral Photobiomodulation in Management of Oral Adverse Effects in Patients Undergoing HSCT | NCT05759975 | Oral Mucositis Hematopoietic N... Xerostomia Hyposalivation | Photobiomodulat... Photobiomodulat... | 18 Years - 90 Years | Federal University of Rio Grande do Sul | |
| Effect of Low-level Laser Therapy on Salivary Flow, pH and Quality of Life in Irradiated Oropharyngeal Cancer Patients | NCT04738227 | Xerostomia | Low-Level Laser... | 18 Years - | Ziauddin University |
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