Symptoms and General Pathology

All Conditions

Necrosis

Hernia

Hernia, Inguinal

Pathological Conditions, Anatomical

Hernia, Abdominal

Patients operated laparoscopically - PIRS technique

Patients operated by open modified Marcy technique

Operation by its known design for PIRS group

Operation - PIRS

Operation by its known design for MARCY group

Operation - MARCY

Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access. Investigators would compare both groups to find out witch one does the lesser inflammatory stress response on the organism.

Inguinal hernia represents the protrusion of the abdominal cavity contents through the inguinal canal. Today there are various surgical techniques for inguinal hernia. In this study, investigators want to compare two standard methods that are regularly performed at the University hospital of Split at department of pediatric surgery. These are the ''PIRS'' operating technique laparoscopy and modified "Marcy" operating technique with open inguinal access. The choice of operating technique depends solely on the choice of a chosen pediatric surgeon. Given the fact that the child is indicated for an operation, regardless of participation in the study, there are no significant risks of participating in this study, except for possible but rare complications resulting from the peripheral venous blood draw (haematoma, soreness and pain). To carry out this study, the child should be taken (drawn) 3 peripheral venous blood samples (on day of operation, 24 hours after surgery and 6 days after surgery) from which the laboratory parameters are taken and counted (Leukocytes, C - Reactive Protein, Interleukin 6 and Tumor necrosis factor α).

Lab results would be compared between both groups to find out witch one does the lesser inflammatory stress response on the organism.

Inflammatory Stress Response in Pediatric Inguinal Hernia Repair

Comparison of Inflammatory Stress Response Between Laparoscopic and Open Approach for Pediatric Inguinal Hernia Repair

Just investigators have insight in patient data, no such data (names and private data) would be written in the study for publishing

measurement of IL6 in pg/mL (according to manufacturer), change of the value in three time frames like mentioned below

measurement of C - reactive protein in mg/L, change of the value in three time frames like mentioned below

measurement of Tumor necrosis factor alpha in pg/mL (according to manufacturer), change of the value in three time frames like mentioned below

measurement of white blood cell count in 10\^9/L, change of the value in three time frames like mentioned below

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Inflammatory Stress Response in Pediatric Inguinal Hernia Repair	NCT03203343	Inguinal Hernia... Children, Only Inflammatory Re... Surgery Interleukin-6 Tumor Necrosis ... C Reactive Prot... White Blood Cel...	Operation - PIR... Operation - MAR...	3 Years - 7 Years	University Hospital of Split
Inflammatory Stress Response in Pediatric Inguinal Hernia Repair	NCT03203343	Inguinal Hernia... Children, Only Inflammatory Re... Surgery Interleukin-6 Tumor Necrosis ... C Reactive Prot... White Blood Cel...	Operation - PIR... Operation - MAR...	3 Years - 7 Years	University Hospital of Split

Spots Global Cancer Trial Database for white blood cell count, leukocytes