Heart and Blood Diseases

All Conditions

Symptoms and General Pathology

Nervous System Diseases

Neoplasms

Rare Diseases

Coronary Artery Disease

Hypertension

Aortic Dissection

Cardiomyopathies

Heart Diseases

Arrhythmias, Cardiac

Ischemia

Cerebrovascular Disorders

Coronary Disease

Myocardial Ischemia

Heart Valve Diseases

Brain Neoplasms

Myocarditis

Heart Neoplasms

Vascular Diseases

Arteriosclerosis

Arterial Occlusive Diseases

Dissection, Blood Vessel

Aneurysm

Syndrome

Acute Aortic Syndrome

Aortic Diseases

Central Nervous System Neoplasms

Nervous System Neoplasms

Brain Diseases

Central Nervous System Diseases

Thoracic Neoplasms

Heart Tumor

Acute Graft Versus Host Disease

Diagnosis of coronary artery disease by clinical guidelines.

Diagnosis of arrhythmia by clinical guidelines. by clinical guidelines.

Diagnosis of heart valve disease by clinical guidelines.

Diagnosis of aortic dissection by clinical guidelines.

Diagnosis of cardiac messes by clinical guidelines.

Diagnosis of myocarditis by clinical guidelines.

Diagnosis of hypertension by clinical guidelines.

Diagnosis of cardiomyopathy by clinical guidelines.

Diagnosis of structural heart disease by clinical guidelines.

Diagnosis of ischemic cerebrovascular disease by clinical guidelines.

Diagnosis of hemorrhagic cerebrovascular disease by clinical guidelines.

Diagnosis of intracranial space occupying by clinical guidelines.

Observational; No Interventions were given.

Gouliang Li

Yang Yan

The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.

Cardiovascular and cerebrovascular diseases refer to ischemic and hemorrhagic diseases of the heart, brain and body tissues caused by hyperlipidemia, blood viscosity, atherosclerosis, hypertension, etc. It is one of the major public health problems in the world. The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics (PROSPECT): a National, Multicenter, Retrospective-prospective, Cohort Study

Major adverse cardiovascular and cerebrovascular events, a composite of all-cause mortality, myocardial infarction, coronary revascularization, and stroke.

Incidence of patients' death from any cause.

Changes of serum myocardial zymogram level and ECG were used for diagnosing of myocardial infarction.

Incidence of percutaneous coronary intervention or coronary artery bypass grafting.

Stroke were assessed by radiologist using CT scan or other imaging test.

Xi'an Gaoxin Hospital

First Affiliated Hospital of Chongqing Medical University

General Hospital of Ningxia Medical University

Second Affiliated Hospital of Nanchang University

First Affiliated Hospital Xi'an Jiaotong University

Respiratory Tract (Lung and Bronchial) Diseases

Lung Neoplasms

Aortic Aneurysm

Patients underwent lung surgery including wedge resection, lobectomy, segmentectomy, and pneumonectomy.

Lung surgery

Patients underwent open thoracic surgery or thoracoabdominal aortic surgery.

Open aortic surgery

TEVAR

EVAR

Sirilak Suksompong, MD

Sirilak Suksompong, M.D.

Sirintip Swangwong, M.D.

Lung surgery, open aortic surgery, TEVAR, and EVAR are major operations that carry a higher incidence of perioperative mortality and complications compare to other surgery. The study of the incidence of mortality and complications will help the hospital to benchmark with the others. Also the study of the risk factors of mortality and major complications will help to improve the patients' outcomes.

Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR.

Incidence of Perioperative Mortality and Major Complications in Patients Who Underwent Lung Surgery, Open Thoracic Aortic Repair, Thoracic Endovascular Aortic Repair (TEVAR), and Endovascular Aortic Repair (EVAR). A Retrospective Study

The patients with postoperative delirium required treatment will be described.

Psoas muscle index will be used for the diagnosis of low muscle mass. Psoas muscle index = both psoas muscle area at L3 (from CT scan) divided by body surface area.

Cut-off values of sarcopenia

* Male 68.5 cm2/m2
* Female 52.5 cm2/m2

To identify risk factors eg. smoking, type of surgery, age, etc.

The mortality and major complications (CVS, CNS, RS and others) will be recorded.

To identify risk factors eg. smoking, diagnosis, age, etc.

To identify risk factors eg. smoking, age, etc.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics	NCT06001073	Coronary Artery... Arrhythmias, Ca... Heart Valve Dis... Aortic Dissecti... Heart Neoplasms Myocarditis Hypertension Cardiomyopathie... Structural Hear... Ischemic Cerebr... Hemorrhagic Cer... Brain Neoplasms	Observational; ...	3 Years - 80 Years	First Affiliated Hospital Xi'an Jiaotong University
Incidence of Mortality and Complications After Lung Surgery, Open Thoracic Aortic Repair, TEVAR, EVAR.	NCT05073991	Morality Lung Cancer Aortic Aneurysm Aortic Dissecti...	Lung surgery Open aortic sur... TEVAR EVAR	18 Years -	Mahidol University

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