Spots Global Cancer Trial Database for chlorambucil
Every month we try and update this database with for chlorambucil cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Combination Chemotherapy With or Without Interferon Alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma | NCT00003639 | Lymphoma | recombinant int... chlorambucil dexamethasone idarubicin | 15 Years - 70 Years | National Cancer Institute (NCI) | |
| Gazyva Infusion Reaction Investigation | NCT03529227 | Chronic Lymphoc... | 18 Years - | Healthy Future | ||
| Chlorambucil + Lenalidomide and Lenalidomide Maintenance in Untreated Elderly With Chronic Lymphocytic Leukemia (CLL) | NCT01403246 | Chronic Lymphoc... | Lenalidomide; C... | 60 Years - | Gruppo Italiano Malattie EMatologiche dell'Adulto | |
| Study Of The Effectiveness & Safety Of Lenalidomide Versus Chlorambucil As First Line Therapy For Elderly Patients With B-Cell CLL (The ORIGIN Trial) | NCT00910910 | B-Cell Chronic ... | Lenalidomide Chlorambucil | 65 Years - | Celgene | |
| A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia | NCT01905943 | Chronic Lymphoc... | Bendamustine Chlorambucil Cyclophosphamid... Fludarabine Obinutuzumab | 18 Years - | Hoffmann-La Roche | |
| Chlorambucil or Fludarabine as First-Line Therapy in Treating Patients With Previously Untreated Waldenström Macroglobulinemia, Splenic Lymphoma, or Lymphoplasmacytic Lymphoma | NCT00608374 | Lymphoma | chlorambucil fludarabine pho... quality-of-life... | 18 Years - | National Cancer Institute (NCI) | |
| Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial) | NCT04692740 | Pancreatic Duct... | Chlorambucil, O... | 18 Years - | IRCCS San Raffaele | |
| CLL11: A Study of Rituximab With Chlorambucil or Chlorambucil Alone in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1b) | NCT01998880 | Lymphocytic Leu... | obinutuzumab rituximab chlorambucil | 18 Years - | Hoffmann-La Roche | |
| Bendamustine Hydrochloride Injection for Initial Treatment of Chronic Lymphocytic Leukemia | NCT01109264 | Chronic Lymphoc... | Bendamustine hy... Chlorambucil | 18 Years - 75 Years | Jiangsu Simcere Pharmaceutical Co., Ltd. | |
| Combination Chemotherapy With or Without Interferon Alfa in Treating Patients With Low-Grade Non-Hodgkin's Lymphoma | NCT00003639 | Lymphoma | recombinant int... chlorambucil dexamethasone idarubicin | 15 Years - 70 Years | National Cancer Institute (NCI) | |
| A Study of MabThera (Rituximab) Plus Chlorambucil in Participants With Chronic Lymphocytic Leukemia. | NCT00532129 | Lymphocytic Leu... | Rituximab Chlorambucil | 18 Years - | Hoffmann-La Roche | |
| Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial) | NCT04692740 | Pancreatic Duct... | Chlorambucil, O... | 18 Years - | IRCCS San Raffaele | |
| Comparison of the Treatments of Obinutuzumab + Venetoclax Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia | NCT02242942 | Lymphocytic Leu... | Chlorambucil Venetoclax Obinutuzumab | 18 Years - | Hoffmann-La Roche | |
| Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL) | NCT00151736 | Chronic Lymphoc... | Chlorambucil R-etodolac + ch... | 18 Years - | Teva Branded Pharmaceutical Products R&D, Inc. | |
| CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a) | NCT01010061 | Lymphocytic Leu... | obinutuzumab rituximab chlorambucil | 18 Years - | Hoffmann-La Roche | |
| Ublituximab + TGR-1202 Compared to Obinutuzumab + Chlorambucil in Participants With Untreated and Previously Treated Chronic Lymphocytic Leukemia | NCT02612311 | Chronic Lymphoc... | Obinutuzumab Ublituximab TGR-1202 Chlorambucil | 18 Years - | TG Therapeutics, Inc. | |
| Chlorambucil Compared With Radiation Therapy in Treating Patients With Previously Untreated Stage III or Stage IV Follicular Lymphoma | NCT00028691 | Lymphoma | chlorambucil radiation thera... | 18 Years - | National Cancer Institute (NCI) | |
| A Study of MabThera (Rituximab) Plus Chlorambucil in Participants With Chronic Lymphocytic Leukemia. | NCT00532129 | Lymphocytic Leu... | Rituximab Chlorambucil | 18 Years - | Hoffmann-La Roche | |
| Study of Acalabrutinib Versus Chlorambucil Plus Rituximab in Adult Subjects With Previously Untreated Chronic Lymphocytic Leukemia | NCT04075292 | Untreated Chron... | Acalabrutinib Rituximab Chlorambucil | 18 Years - 130 Years | AstraZeneca | |
| Chlorambucil in Treating Patients With Advanced Chronic Lymphocytic Leukemia | NCT00017108 | Leukemia | chlorambucil cyclophosphamid... fludarabine pho... | 18 Years - 75 Years | National Cancer Institute (NCI) | |
| A Study Evaluating the Safety of Tocilizumab in Addition to Standard of Care Premedication Given Before Obinutuzumab + Chlorambucil in Participants With Untreated B-Cell Chronic Lymphocytic Leukemia (B-CLL) and Comorbidities | NCT02336048 | B-Cell Chronic ... | Chlorambucil Obinutuzumab Placebo Standard Premed... Tocilizumab | 18 Years - | Hoffmann-La Roche | |
| Study to Investigate Idelalisib in Combination With Chemotherapeutic Agents, Immunomodulatory Agents and Anti-CD20 Monoclonal Antibody (mAb) in Participants With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma, Mantle Cell Lymphoma or Chronic Lymphocytic Leukemia | NCT01088048 | Indolent Non-Ho... Chronic Lymphoc... Mantle Cell Lym... | Idelalisib Rituximab Bendamustine Ofatumumab Fludarabine Everolimus Bortezomib Chlorambucil Lenalidomide | 18 Years - | Gilead Sciences | |
| Study of Acalabrutinib Versus Chlorambucil Plus Rituximab in Adult Subjects With Previously Untreated Chronic Lymphocytic Leukemia | NCT04075292 | Untreated Chron... | Acalabrutinib Rituximab Chlorambucil | 18 Years - 130 Years | AstraZeneca | |
| Safety and Efficacy of SDX-101 (R-Etodolac) in Combination With Chlorambucil, and That of Chlorambucil Alone, in Patients With Chronic Lymphocytic Leukemia (CLL) | NCT00151736 | Chronic Lymphoc... | Chlorambucil R-etodolac + ch... | 18 Years - | Teva Branded Pharmaceutical Products R&D, Inc. | |
| A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia | NCT01905943 | Chronic Lymphoc... | Bendamustine Chlorambucil Cyclophosphamid... Fludarabine Obinutuzumab | 18 Years - | Hoffmann-La Roche | |
| Chlorambucil Compared With No Further Therapy Following Anti-Helicobacter Therapy in Treating Patients With Low-Grade Lymphoma of the Stomach | NCT00003617 | Gastric Cancer | chlorambucil clarithromycin omeprazole tinidazole | 16 Years - | National Cancer Institute (NCI) | |
| Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia | NCT00004218 | Leukemia | chlorambucil cyclophosphamid... doxorubicin hyd... fludarabine pho... prednisolone vincristine sul... | - | National Cancer Institute (NCI) | |
| CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a) | NCT01010061 | Lymphocytic Leu... | obinutuzumab rituximab chlorambucil | 18 Years - | Hoffmann-La Roche | |
| Efficacy and Safety of Idelalisib in Combination With Obinutuzumab Compared to Chlorambucil in Combination With Obinutuzumab for Previously Untreated Chronic Lymphocytic Leukemia | NCT01980875 | Chronic Lymphoc... | Idelalisib Chlorambucil Obinutuzumab | 18 Years - | Gilead Sciences | |
| Dose Escalation Study of Gleevec and Chlorambucil in Previously Treated Chronic Lymphocytic Leukemia Patients | NCT00558961 | Chronic Lymphoc... | Gleevec and Chl... | 18 Years - | Jewish General Hospital | |
| Trial Comparing Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia | NCT00566332 | Waldenström Mac... Lymphoplasmacyt... Splenic Margina... | Chlorambucil Fludarabine | 18 Years - | French Study Group on Chronic Lymphoid Leukemia | |
| CLL11: A Study of Rituximab With Chlorambucil or Chlorambucil Alone in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1b) | NCT01998880 | Lymphocytic Leu... | obinutuzumab rituximab chlorambucil | 18 Years - | Hoffmann-La Roche | |
| An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia | NCT01868893 | Chronic Lymphoc... | Obinutuzumab Chlorambucil | 18 Years - | Genentech, Inc. | |
| Dose Escalation Study of Gleevec and Chlorambucil in Previously Treated Chronic Lymphocytic Leukemia Patients | NCT00558961 | Chronic Lymphoc... | Gleevec and Chl... | 18 Years - | Jewish General Hospital | |
| A Trial Looking at Ofatumumab for People With Chronic Lymphocytic Leukaemia Who Cannot Have More Intensive Treatment | NCT01678430 | Chronic Lymphoc... | Ofatumumab Chlorambucil Bendamustine | 18 Years - | University of Liverpool | |
| Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial) | NCT04692740 | Pancreatic Duct... | Chlorambucil, O... | 18 Years - | IRCCS San Raffaele | |
| Bendamustine Hydrochloride Injection for Initial Treatment of Chronic Lymphocytic Leukemia | NCT01109264 | Chronic Lymphoc... | Bendamustine hy... Chlorambucil | 18 Years - 75 Years | Jiangsu Simcere Pharmaceutical Co., Ltd. | |
| Comparison of the Treatments of Obinutuzumab + Venetoclax Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic Leukemia | NCT02242942 | Lymphocytic Leu... | Chlorambucil Venetoclax Obinutuzumab | 18 Years - | Hoffmann-La Roche | |
| An Expanded Access, Open-Label Study of Obinutuzumab (GA101) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia | NCT01868893 | Chronic Lymphoc... | Obinutuzumab Chlorambucil | 18 Years - | Genentech, Inc. | |
| A Safety and Efficacy Study of Obinutuzumab Alone or in Combination With Chemotherapy in Participants With Chronic Lymphocytic Leukemia | NCT01905943 | Chronic Lymphoc... | Bendamustine Chlorambucil Cyclophosphamid... Fludarabine Obinutuzumab | 18 Years - | Hoffmann-La Roche | |
| A Multi-Center Study of Ibrutinib in Combination With Obinutuzumab Versus Chlorambucil in Combination With Obinutuzumab in Patients With Treatment naïve Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) | NCT02264574 | Chronic Lymphoc... Small-Cell Lymp... | Ibrutinib Obinutuzumab Chlorambucil | 18 Years - | Pharmacyclics LLC. | |
| Phase II Study of Chlorambucil and Subcutaneous Rituximab in Patients With Extranodal MALT Lymphoma | NCT01808599 | MALT Lymphoma | Chlorambucil Rituximab i.v. Rituximab s.c. | 18 Years - | International Extranodal Lymphoma Study Group (IELSG) | |
| CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2) | NCT02053610 | Lymphocytic Leu... | obinutuzumab rituximab chlorambucil | 18 Years - | Hoffmann-La Roche | |
| A Study of Obinutuzumab Evaluating Efficacy, Safety and Cost of Disease Management in Participants With Chronic Lymphocytic Leukemia and Comorbidities | NCT02915224 | Chronic Lymphoc... | Chlorambucil Obinutuzumab | 18 Years - | Hoffmann-La Roche |
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