Neoplasms

All Conditions

Skin and Connective Tissue Diseases

Rare Diseases

Chondrosarcoma

Chordoma

Neoplasms, Connective Tissue

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Sarcoma

Neoplasms, Germ Cell and Embryonal

Soft Tissue Sarcoma

Proton radiation total dose 72.00 to 79.2 Gy(RBE) in 40-44 fractions

Proton Therapy

The objectives of this study are 1) To evaluate the feasibility and acute side effects of proton therapy for chordomas and chondrosarcomas and 2) To evaluate clinical outcomes and long term side effects of proton beam radiation for treatment of chordomas and chondrosarcomas.

This trial will be conducted in two phases: a feasibility then a phase II trial. Once feasibility and safety are established in the first 12 pts. the phase II study will begin. Proton therapy at standard doses is not known to improve clinical outcome but will likely reduce fatigue and toxicity.

Proton Radiation for Chordomas and Chondrosarcomas

Proton Radiation For Chordomas and Chondrosarcomas

Any grade 3 or higher toxicity observed within 90 days from start of therapy.

Any grade 3 or higher toxicty observed later than 90 days from completion of therapy.

Abramson Cancer Center at Penn Medicine

Ronny L Rotondo, MD

The purpose of this study is to collect information from medical records to see what effects proton beam radiation has on cancer and analyze possible side effects.

Data collection will be obtained from the patient's medical records including initial evaluation, pathology report, dosimetry information, radiotherapy completion records and follow-up.

Proton Therapy for Chordomas and/or Chondrosarcomas

A Clinical Outcomes Protocol of Proton Beam Radiation Therapy for Chordomas and/or Chondrosarcomas of the Base of Skull and/or Spine

Specifically analyzing pituitary, visual and hearing function.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Proton Radiation for Chordomas and Chondrosarcomas	NCT01449149	Chordomas Chondrosarcomas	Proton Therapy	18 Years -	Abramson Cancer Center at Penn Medicine
Proton Therapy for Chordomas and/or Chondrosarcomas	NCT00797602	Chordomas Chondrosarcomas		18 Years -	University of Florida
Proton Radiation for Chordomas and Chondrosarcomas	NCT01449149	Chordomas Chondrosarcomas	Proton Therapy	18 Years -	Abramson Cancer Center at Penn Medicine

Spots Global Cancer Trial Database for chordomas

Every month we try and update this database with for chordomas cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for chordomas

Every month we try and update this database with for chordomas cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for chordomas cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.