Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Eye Diseases

Rare Diseases

Melanoma

Retinal Diseases

Uveal Neoplasms

Neuroendocrine Tumors

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Nerve Tissue

Nevus, Pigmented

Nevus

Nevi and Melanomas

Skin Neoplasms

Skin Diseases

Eye Neoplasms

Uveal Diseases

Intraocular Melanoma

Neuroendocrine Tumor

Neuroepithelioma

Patients with newly diagnosed uveal melanoma, which will be treated with hypofractionated stereotactic photon radiotherapy as clinical routine.

Imaging consists of sonography, fundus photography, oximeter, optical coherence tomography angiography, and Microperimetry.

Clinical examination and multimodal ocular imaging

Judith Kreminger, MD

Reinhard Told, MD, PhD

Reinhard Told, MD, PhD, Priv.-Doz.

Adrian Reumueller, MD, Priv.-Doz

Roman Dunavoelgyi, MD, Assoc.-Prof.

The purpose of this study is to evaluate the incidence and severity of retinopathy and opticopathy one year after treatment with hypofractionated stereotactic photon radiotherapy due to uveal melanoma. Patients will be imaged before radiation, as well as 3, 6, 9 and 12 months after radiation using sonography funds photography, optical coherence tomography angiography, oximeter and microperimetry.

Longitudinal Follow-Up of Patients Treated With Hypofractionated Stereotactic Photon Radiotherapy Due to Uveal Melanoma

Longitudinal Follow-Up of Retinopathy and Opticopathy After Treatment With Hypofractionated Stereotactic Photon Radiotherapy Due to Uveal Melanoma

Incidence and severity of retinopathy will be evaluated as non-perfusion areas on optical coherence tomography angiography

Incidence and severity of retinopathy will be evaluated on clinical examination and fundus photography

Functional outcome will be evaluated as mean retinal sensitivity.

Incidence and severity of retinopathy and opticopathy will be evaluated using oxygen saturation

Medical University of Vienna

MD, PHD

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Longitudinal Follow-Up of Patients Treated With Hypofractionated Stereotactic Photon Radiotherapy Due to Uveal Melanoma	NCT06280040	Uveal Melanoma	Clinical examin...	18 Years -	Medical University of Vienna
Longitudinal Follow-Up of Patients Treated With Hypofractionated Stereotactic Photon Radiotherapy Due to Uveal Melanoma	NCT06280040	Uveal Melanoma	Clinical examin...	18 Years -	Medical University of Vienna

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