Spots Global Cancer Trial Database for diffuse midline glioma
Every month we try and update this database with for diffuse midline glioma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository | NCT03101813 | Diffuse Intrins... Diffuse Midline... Diffuse Midline... | - | Children's Hospital Medical Center, Cincinnati | ||
| xPedite: A Study to Expedite DIPG and DMG Research | NCT06140719 | Oncology DIPG DMG | - | xCures | ||
| A MultIceNTER Phase I Peptide VaCcine Trial for the Treatment of H3-Mutated Gliomas | NCT04808245 | Newly Diagnosed... | Tecentriq 1200 ... H3K27M peptide ... Imiquimod (5%) | 18 Years - | German Cancer Research Center | |
| rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG | NCT04943848 | Diffuse Intrins... Diffuse Midline... | rHSC-DIPGVax Balstilimab Zalifrelimab | 12 Months - 18 Years | Ann & Robert H Lurie Children's Hospital of Chicago | |
| CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas | NCT04264143 | Diffuse Intrins... Diffuse Pontine... Diffuse Midline... | Infusate with M... Convection-Enha... | 3 Years - 18 Years | Columbia University | |
| A Study of the Safety, Dosing, and Delivery of NEO100 in Patients With Pediatric Brain Tumors | NCT06357377 | Pediatric Tumor... Pediatric Tumor... Diffuse Midline... Pediatric Tumor... Pineocytoma Choroid Plexus ... Spinal Cord Tum... High Grade Glio... | NEO100 | 5 Years - 18 Years | Neonc Technologies, Inc. | |
| International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) | NCT03243461 | Glioblastoma WH... Diffuse Midline... Anaplastic Astr... Diffuse Intrins... Gliomatosis Cer... | Temozolomide + ... | 3 Years - 17 Years | University of Göttingen | |
| Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors | NCT05768880 | Diffuse Intrins... Diffuse Midline... Recurrent CNS T... Recurrent, CNS ... Refractory Prim... | SC-CAR4BRAIN | 1 Year - 26 Years | Seattle Children's Hospital | |
| CAR T Cells to Target GD2 for DMG | NCT05544526 | Diffuse Midline... | GD2 CAR T cells | - 16 Years | University College, London | |
| Oral ONC201 in Recurrent GBM, H3 K27M Glioma, and Midline Glioma | NCT02525692 | Glioblastoma Diffuse Midline... H3 K27M Glioma Thalamic Glioma Infratentorial ... Basal Ganglia G... | ONC201 | 16 Years - | Chimerix | |
| International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry and Repository | NCT03101813 | Diffuse Intrins... Diffuse Midline... Diffuse Midline... | - | Children's Hospital Medical Center, Cincinnati | ||
| Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors | NCT05768880 | Diffuse Intrins... Diffuse Midline... Recurrent CNS T... Recurrent, CNS ... Refractory Prim... | SC-CAR4BRAIN | 1 Year - 26 Years | Seattle Children's Hospital |
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