Spots Global Cancer Trial Database for methotrexate
Every month we try and update this database with for methotrexate cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma | NCT00335140 | Lymphoma | Rituximab Cytarabine Dexamethasone Leucovorin Methotrexate Procarbazine Vincristine | 18 Years - | Eastern Cooperative Oncology Group | |
| Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia | NCT02877303 | B Acute Lymphob... B Lymphoblastic... | Blinatumomab Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Inotuzumab Ozog... Laboratory Biom... Mercaptopurine Methotrexate Ofatumumab Prednisone Rituximab Vincristine Sul... | 14 Years - | M.D. Anderson Cancer Center | |
| Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors | NCT02458339 | Brain Tumor, Re... Malignant Neopl... | Ommaya Reservoi... Methotrexate | 1 Year - 21 Years | The University of Texas Health Science Center, Houston | |
| Radiolabeled Monoclonal Antibody, Cyclophosphamide, and Total Body Irradiation Followed By Donor Stem Cell Transplantation in Treating Patients With Advanced Acute Myeloid Leukemia | NCT00003868 | Leukemia | cyclophosphamid... methotrexate allogeneic bone... peripheral bloo... iodine I 131 mo... radiation thera... | 2 Years - 55 Years | Fred Hutchinson Cancer Center | |
| N-PhenoGENICS: Neurocognitive-Phenome, Genome, Epigenome and Nutriome In Childhood Leukemia Survivors | NCT01913093 | Childhood Leuke... | 8 Years - 20 Years | The Hospital for Sick Children | ||
| Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation | NCT03842696 | Hematologic Dis... Acute Leukemia ... Chronic Myeloge... Chronic Myeloge... Chronic Myeloge... Myelodysplastic... Mantle Cell Lym... Follicular Lymp... Diffuse Large B... Non Hodgkin Lym... Graft Vs Host D... Graft-versus-ho... | Vorinostat Blood and Marro... Tacrolimus (or ... Methotrexate Mycophenolate M... Cyclophosphamid... | 3 Years - 39 Years | University of Michigan Rogel Cancer Center | |
| Freiburg ZNS-NHL Study | NCT00647049 | Primary Non Hod... | methotrexate Rituximab Cytarabine Thiotepa Carmustin | 18 Years - 65 Years | University Hospital Freiburg | |
| Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma | NCT03719105 | NK-Cell Lymphom... NK-Cell Leukemi... Peripheral T Ce... | Methotrexate pralatraxate, Ifosfamide Dexamethasone Etoposide calaspargase pe... cyclophosphamid... Doxorubicin Prednisone Brentuximab Ved... | 1 Year - 31 Years | New York Medical College | |
| Combination Chemotherapy in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia | NCT00040690 | Leukemia Lymphoma | filgrastim cyclophosphamid... cytarabine doxorubicin hyd... etoposide ifosfamide leucovorin calc... methotrexate vincristine sul... radiation thera... | 16 Years - | National Cancer Institute (NCI) | |
| Methotrexate With or Without Antineoplaston Therapy in Treating Postmenopausal Women With Advanced Refractory Breast Cancer | NCT00003536 | Stage IV Breast... Recurrent Breas... | antineoplaston ... methotrexate alternative pro... biological ther... biologically ba... cancer preventi... chemotherapy complementary a... differentiation... | - | National Cancer Institute (NCI) | |
| NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma | NCT01451515 | Lymphoblastic L... | Prednisone Vincristine Daunorubicin PEG-asparaginas... Erwinia asparag... Doxorubicin Cyclophosphamid... Cytarabine Thioguanine Clofarabine Methotrexate Mercaptopurine Dexamethasone Hydrocortisone Etoposide | - 21 Years | St. Jude Children's Research Hospital | |
| Study to Assess Compliance With Long-Term Mercaptopurine Treatment in Young Patients With Acute Lymphoblastic Leukemia in Remission | NCT00268528 | Childhood Acute... | Compliance Moni... Laboratory Biom... Mercaptopurine Methotrexate Questionnaire A... Study of Socioe... | - 21 Years | Children's Oncology Group | |
| Trial to Evaluate Palifermin in the Reduction of Acute Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Allogeneic Marrow/Peripheral Blood Progenitor Cell (PBPC) Transplantation | NCT00189488 | Graft Versus Ho... Hematologic Mal... | Palifermin Placebo Conditioning Re... Allogeneic stem... Methotrexate | 18 Years - | Swedish Orphan Biovitrum | |
| Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL) | NCT06210750 | T Acute Lymphob... T Lymphoblastic... | Biospecimen Col... Bone Marrow Asp... Bone Marrow Bio... Calaspargase Pe... Computed Tomogr... Cyclophosphamid... Cytarabine Daunorubicin Dexamethasone Doxorubicin Echocardiograph... Lumbar Puncture Mercaptopurine Methotrexate Multigated Acqu... Navitoclax Nelarabine Pegaspargase Positron Emissi... Thioguanine Venetoclax Vincristine X-Ray Imaging | 18 Years - 60 Years | National Cancer Institute (NCI) | |
| Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia | NCT00002785 | Leukemia | filgrastim asparaginase cyclophosphamid... cyclosporine cytarabine daunorubicin hy... dexamethasone etoposide leucovorin calc... mercaptopurine mesna methotrexate methylprednisol... pegaspargase prednisone therapeutic hyd... vincristine sul... allogeneic bone... low-LET cobalt-... low-LET photon ... | - 1 Year | Children's Oncology Group | |
| Combination Chemotherapy and Imatinib Mesylate in Treating Children With Relapsed Acute Lymphoblastic Leukemia | NCT00049569 | L1 Childhood Ac... L2 Childhood Ac... Non-T, Non-B Ch... Recurrent Child... T-cell Childhoo... | cytarabine methotrexate vincristine sul... prednisone pegaspargase doxorubicin hyd... imatinib mesyla... cyclophosphamid... etoposide filgrastim leucovorin calc... asparaginase therapeutic hyd... | 1 Year - 21 Years | National Cancer Institute (NCI) | |
| A Study in Adults With Untreated Acute Lymphoblastic Leukemia | NCT00136435 | Acute Lymphobla... | prednisone doxorubicin vincristine methotrexate asparaginase dexamethasone cranial radiati... leucovorin cytarabine hydrocortisone 6-mercaptopurin... e. coli L-aspar... | 18 Years - 50 Years | Dana-Farber Cancer Institute | |
| Ofatumumab in Combination With Cyclophosphamide, Doxorubicin Hydrochloride, Vincristine Sulfate, and Dexamethasone Alternating With Ofatumumab in Combination With Cytarabine and Methotrexate in Treating Patients With Newly Diagnosed Mantle Cell Lymphoma | NCT01527149 | Stage I Mantle ... Stage II Contig... Stage II Non-Co... Stage III Mantl... Stage IV Mantle... | Autologous Hema... Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Laboratory Biom... Methotrexate Ofatumumab Vincristine Sul... | 18 Years - 70 Years | Roswell Park Cancer Institute | |
| Combination Chemotherapy Based on Risk of Relapse in Treating Young Patients With Acute Lymphoblastic Leukemia | NCT00613457 | Leukemia | dexamethasone asparaginase Asparaginase cyclophosphamid... cytarabine daunorubicin doxorubicin Etoposide Ifosfamide mercaptopurine Methotrexate prednisone thioguanine Vincristine Vindesine | 1 Year - 17 Years | Associazione Italiana Ematologia Oncologia Pediatrica | |
| Chidamide Combined With PECM in Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL) | NCT03321890 | Peripheral T-ce... | Chidamide prednisone Cyclophosphamid... etoposide Methotrexate | 18 Years - 75 Years | Sun Yat-sen University | |
| Cyclophosphamide and Busulfan Followed by Donor Stem Cell Transplant in Treating Patients With Myelofibrosis, Acute Myeloid Leukemia, or Myelodysplastic Syndrome | NCT00445744 | Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Childhood Acute... Childhood Myelo... de Novo Myelody... Essential Throm... Myelodysplastic... Polycythemia Ve... Previously Trea... Primary Myelofi... Recurrent Adult... Recurrent Child... Secondary Acute... Secondary Myelo... Secondary Myelo... Untreated Adult... Untreated Child... | cyclophosphamid... busulfan tacrolimus methotrexate cytogenetic ana... flow cytometry pharmacological... pharmacogenomic... peripheral bloo... allogeneic hema... | - 65 Years | Fred Hutchinson Cancer Center | |
| A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma | NCT00667342 | Osteosarcoma Malignant Fibro... | Bevacizumab Cisplatin Doxorubicin Methotrexate Ifosfamide etoposide Surgery Radiotherapy | - 30 Years | St. Jude Children's Research Hospital | |
| Reduced Intensity Conditioning Allogeneic Hematopoietic Stem Cell Transplant (HSCT) For Lymphoma | NCT02724904 | Lymphoma | Allogeneic stem... Fludarabine Thiotepa Methotrexate | 18 Years - | Massachusetts General Hospital | |
| A Clinical Trial in Patients With Breast Cancer Susceptibility Gene (BRCA) Defective Tumours | NCT01432145 | Breast Cancer Ovarian Cancer | 6-Mercaptopurin... Methotrexate | 18 Years - | University of Oxford | |
| Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma | NCT00006184 | Multiple Myelom... | Myeloma Immunog... Bortezomib Cyclophosphamid... Cyclosporine Doxorubicin hyd... Etoposide Fludarabine pho... Prednisone Vincristine Sul... Methotrexate GMCSF (granuloc... GCSF (granulocy... | 18 Years - 75 Years | National Institutes of Health Clinical Center (CC) | |
| S9716: Combination Chemotherapy in Treating Patients With Merkel Cell Cancer | NCT00003549 | Neuroendocrine ... | CMF regimen cyclophosphamid... fluorouracil methotrexate | 18 Years - | SWOG Cancer Research Network | |
| A Study of Safety and Effectiveness of Golimumab in Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy | NCT00361335 | Rheumatoid Arth... | Golimumab Methotrexate Placebo | 18 Years - | Centocor, Inc. | |
| ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016 | NCT03286634 | Down Syndrome Acute Lymphobla... Childhood Cance... | Daunorubicin Prednisolone Vincristine Epirubicin E-coli L-aspara... 6-Mercaptopurin... Methotrexate Hydrocortisone Cytarabine Cyclophosphamid... | 0 Years - 20 Years | National Hospital Organization Nagoya Medical Center | |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma | NCT00408005 | T Acute Lymphob... T Lymphoblastic... | Asparaginase Cyclophosphamid... Cytarabine Daunorubicin Hy... Dexamethasone Doxorubicin Hyd... Laboratory Biom... Leucovorin Calc... Mercaptopurine Methotrexate Nelarabine Pegaspargase Prednisone Radiation Thera... Thioguanine Vincristine Sul... | 1 Year - 30 Years | National Cancer Institute (NCI) | |
| Fludarabine and Busulfan Followed by Allogeneic Stem Cell Transplant in Treating Older Patients With Acute Myeloid Leukemia in First Complete Remission | NCT00070135 | Adult Acute Mye... Acute Myeloid L... | filgrastim Anti-Thymocyte ... busulfan fludarabine pho... methotrexate tacrolimus Allogeneic Hema... | 60 Years - 74 Years | Alliance for Clinical Trials in Oncology | |
| Combination Chemotherapy in Patients With Advanced or Recurrent Mycosis Fungoides | NCT00002557 | Lymphoma | CHOP regimen doxorubicin hyd... etoposide leucovorin calc... methotrexate | - | National Cancer Institute (NCI) | |
| Allo-HSCT With Alternative Donor in Treatment of Hematologic Malignancy | NCT02487069 | Acute Leukemia Chronic Myeloid... Myelodysplastic... | HSCT from MSD HSCT from MUD HSCT from HRD Cyclosporin A Methotrexate Antithymocyte g... Mycophenolate m... | 18 Years - 60 Years | Nanfang Hospital, Southern Medical University | |
| Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma | NCT00275106 | Lymphoma | asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... leucovorin calc... mercaptopurine methotrexate prednisolone thioguanine vincristine sul... radiation thera... | - 21 Years | National Cancer Institute (NCI) | |
| A Phase II Multicenter Study of Chemotherapy Versus Chemotherapy Plus Durvalumab (MEDI 4736) in Patients With Lymph Node Positive Urothelial Carcinoma of the Bladder | NCT05137262 | Urothelial Carc... Bladder Cancer | Abiraterone ace... Durvalumab Methotrexate Vinblastine Doxorubicin Hyd... Cisplatin | 18 Years - | M.D. Anderson Cancer Center | |
| Early Systemic Central Nervous System Prophylaxis in Diffuse Large B-cell Lymphoma | NCT03719560 | Diffuse Large B... | Methotrexate Cytarabine | 18 Years - | Brown University | |
| Nonmyeloablative Allo SCT for the Treatment of Hematologic Disorders | NCT00636909 | AML ALL CML Chronic Pha... CLL MDS RELAPSED NON-HO... APLASTIC ANEMIA MULTIPLE MYELOM... MYELOPROLIFERAT... | Cyclophosphamid... fludarabine cyclosporine methotrexate G-CSF | - 65 Years | Beth Israel Deaconess Medical Center | |
| Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma | NCT02504359 | Plasma Cell Leu... Recurrent Plasm... | Allogeneic Hema... Carmustine Cytarabine Etoposide Ixazomib Citrat... Melphalan Methotrexate Peripheral Bloo... Quality-of-Life... Tacrolimus | 18 Years - 65 Years | OHSU Knight Cancer Institute | |
| Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia | NCT00381680 | B-cell Childhoo... L1 Childhood Ac... L2 Childhood Ac... Intermediate Ri... | vincristine sul... prednisone doxorubicin hyd... pegaspargase cytarabine methotrexate dexamethasone etoposide cyclophosphamid... leucovorin calc... filgrastim asparaginase mercaptopurine | 1 Year - 29 Years | Children's Oncology Group | |
| High-Dose Methotrexate in Treating Young Patients With Solid Tumors | NCT00513981 | Brain and Centr... Sarcoma Unspecified Chi... | leucovorin calc... methotrexate mass spectromet... pharmacological... | - 21 Years | National Cancer Institute (NCI) | |
| Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia | NCT04898894 | Acute Leukemia ... Acute Myeloid L... Refractory Acut... Refractory Acut... | Venetoclax Selinexor Cytarabine Fludarabine Filgrastim Methotrexate methotrexate/hy... | 2 Years - 30 Years | St. Jude Children's Research Hospital | |
| Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia | NCT00002756 | Leukemia | filgrastim asparaginase cyclophosphamid... cytarabine daunorubicin hy... etoposide leucovorin calc... mercaptopurine methotrexate prednisone therapeutic hyd... vincristine sul... | - 1 Year | Children's Oncology Group | |
| Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors | NCT02458339 | Brain Tumor, Re... Malignant Neopl... | Ommaya Reservoi... Methotrexate | 1 Year - 21 Years | The University of Texas Health Science Center, Houston | |
| Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients | NCT02690922 | ph+ Acute Lymph... | Dasatinib prednisone dexamethasone methotrexate | 18 Years - | Tongji Hospital | |
| Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia | NCT02981628 | Recurrent B Acu... Recurrent B Lym... Refractory B Ac... Refractory B Ly... | Asparaginase Er... Biospecimen Col... Bone Marrow Asp... Calaspargase Pe... Cyclophosphamid... Cytarabine Diagnostic Imag... Inotuzumab Ozog... Leucovorin Calc... Lumbar Puncture Methotrexate Pegaspargase Vincristine | 1 Year - 21 Years | Children's Oncology Group | |
| Isatuximab in Combination With Chemotherapy in Pediatric Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia or Acute Myeloid Leukemia | NCT03860844 | Acute Lymphobla... Acute Myeloid L... | Isatuximab Dexamethasone o... Fludarabine Cytarabine Liposomal dauno... Daunorubicin (n... Idarubicin Filgrastim or e... Mitoxantrone Doxorubicin Vincristine Pegaspargase (P... Cyclophosphamid... Etoposide Methotrexate L - Asparginase Hydroxyurea L - Asparaginas... | 28 Days - 17 Years | Sanofi | |
| Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer | NCT04628767 | Renal Pelvis an... | Biopsy Biospecimen Col... Cisplatin Computed Tomogr... Doxorubicin Hyd... Durvalumab Gemcitabine Hyd... Magnetic Resona... Methotrexate Pegfilgrastim Therapeutic Con... Vinblastine Sul... | 18 Years - | National Cancer Institute (NCI) | |
| Chemotherapy and HAART to Treat AIDS-related Primary Brain Lymphoma | NCT00267865 | AIDS-Related-Pr... | Methotrexate Rituximab Leucovorin | 18 Years - 99 Years | National Institutes of Health Clinical Center (CC) | |
| Combination Chemotherapy in Treating Children With Stage III or Stage IV Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia | NCT00003217 | Leukemia Lymphoma | filgrastim cyclophosphamid... cytarabine dexamethasone doxorubicin hyd... methotrexate vincristine sul... | - 21 Years | Children's Oncology Group | |
| Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell Transplantation | NCT03680092 | GVHD Hematologic Neo... | Cyclophosphamid... abatacept Methotrexate Tacrolimus | 18 Years - | University of California, San Diego | |
| Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia | NCT02101853 | Recurrent B Acu... | Allogeneic Hema... Asparaginase Blinatumomab Cyclophosphamid... Cytarabine Dexamethasone Etoposide Leucovorin Calc... Mercaptopurine Methotrexate Mitoxantrone Mitoxantrone Hy... Pegaspargase Pharmacological... Radiation Thera... Therapeutic Hyd... Thioguanine Vincristine Vincristine Sul... | 1 Year - 31 Years | National Cancer Institute (NCI) | |
| Fludarabine-IV Busulfan ± Clofarabine and Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) | NCT01471444 | Disorder Relate... Leukemia Transplantation... | Fludarabine Clofarabine Busulfan Thymoglobulin Stem Cell Infus... Tacrolimus Methotrexate | 3 Years - 70 Years | M.D. Anderson Cancer Center | |
| PETHEMA LAL-07FRAIL: All Treatment In Fragile Patients Ph' Negative Over 55 Years | NCT01358201 | Acute Lymphobla... | vINCRISTINE Dexamethasone Methotrexate Cytosine arabin... | 55 Years - | PETHEMA Foundation | |
| Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma | NCT05998642 | Non-hodgkin Lym... | Methotrexate Rituximab (wher... Ibrutinib | 18 Years - | Canadian Cancer Trials Group | |
| Radiolabeled BC8 Antibody, Busulfan, Cyclophosphamide Followed by Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia in First Remission | NCT00005940 | Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... Adult Acute Mye... | iodine I 131 mo... busulfan cyclophosphamid... allogeneic bone... allogeneic hema... peripheral bloo... cyclosporine methotrexate laboratory biom... | 16 Years - 55 Years | Fred Hutchinson Cancer Center | |
| A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent | NCT02046603 | Rheumatoid Arth... | Tocilizumab DMARDs Oral Corticoste... Methotrexate | 18 Years - | Hoffmann-La Roche | |
| Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia | NCT03488225 | Acute Lymphobla... B Acute Lymphob... B Acute Lymphob... | Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Inotuzumab Ozog... Laboratory Biom... Leucovorin Calc... Mercaptopurine Methotrexate Ofatumumab Prednisone Rituximab Vincristine Sul... | 16 Years - | M.D. Anderson Cancer Center | |
| Chemotherapy Before Surgery in Treating Patients With High Grade Upper Urinary Tract Cancer | NCT02412670 | High Grade Uppe... | Methotrexate Vinblastine Doxorubicin Cisplatin Gemcitabine Carboplatin Pegfilgrastim Nephroureterect... | 18 Years - | Eastern Cooperative Oncology Group | |
| Vinblastine and Methotrexate in Treating Children With Desmoid Tumors | NCT00003019 | Desmoid Tumor | methotrexate vinblastine sul... | - 21 Years | Children's Oncology Group | |
| Modified Hyper-CVAD (Cyclophosphamide, Vincristine, Adriamycin, and Dexamethasone) Program for Acute Lymphoblastic Leukemia | NCT00671658 | Leukemia Acute Lymphobla... | Rituximab Cyclophosphamid... Doxorubicin Vincristine Dexamethasone Methotrexate (M... Cytarabine G-CSF Mesna Pegylated aspar... Pegfilgrastim Solumedrol | - | M.D. Anderson Cancer Center | |
| Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia | NCT00002744 | Leukemia | asparaginase cyclophosphamid... cytarabine daunorubicin hy... dexamethasone doxorubicin hyd... mercaptopurine methotrexate pegaspargase prednisone therapeutic hyd... thioguanine vincristine sul... low-LET cobalt-... low-LET photon ... | 1 Year - 9 Years | Children's Oncology Group | |
| Combination Chemotherapy in Treating Patients With Early Stage Breast Cancer That Has Been Removed By Surgery | NCT00301925 | Breast Cancer | pegfilgrastim capecitabine cyclophosphamid... epirubicin hydr... fluorouracil methotrexate adjuvant therap... | 18 Years - 120 Years | Institute of Cancer Research, United Kingdom | |
| Comparing ATG or Post-Transplant Cyclophosphamide to Calcineurin Inhibitor-Methotrexate as GVHD Prophylaxis After Myeloablative Unrelated Donor Peripheral Blood Stem Cell Transplantation | NCT03602898 | Acute Lymphobla... Acute Myeloid L... Chronic Myelomo... Chronic Phase C... Hematopoietic a... Myelodysplastic... Myelofibrosis Myeloproliferat... Recurrent Acute... Recurrent Hodgk... Recurrent Non-H... Refractory Acut... Therapy-Related... | Anti-Thymocyte ... Busulfan Cyclophosphamid... Cyclosporine Fludarabine Pho... Methotrexate Peripheral Bloo... Quality-of-Life... Questionnaire A... Tacrolimus Total-Body Irra... | - 65 Years | Fred Hutchinson Cancer Center | |
| Combination Chemotherapy in Treating Patients With Bladder Cancer | NCT00003701 | Bladder Cancer Urethral Cancer | carboplatin cisplatin doxorubicin hyd... methotrexate paclitaxel vinblastine sul... | 0 Years - 120 Years | Eastern Cooperative Oncology Group | |
| Optimization of Therapy in Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatment | NCT02881086 | Acute Lymphobla... Lymphoblastic L... | Rituximab Nelarabine PEG-Asparaginas... Cranial irradia... Imatinib Idarubicin Dexamethasone Cyclophosphamid... Fludarabine Vincristine Mercaptopurine VP16 Daunorubicin (D... Methotrexate Stem cell trans... Cytarabine Vindesine Adriamycin Prednisolone | 18 Years - 55 Years | Goethe University | |
| Pembrolizumab (MK-3475) Versus Standard Treatment for Recurrent or Metastatic Head and Neck Cancer (MK-3475-040/KEYNOTE-040) | NCT02252042 | Head and Neck S... | Pembrolizumab Methotrexate Docetaxel Cetuximab | 18 Years - | Merck Sharp & Dohme LLC | |
| Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow | NCT00003838 | Myeloproliferat... Acute Myelogeno... Chronic Myeloge... Myelodysplastic... Acute Lymphobla... | T-cell replete ... Methotrexate Cyclosporine G-CSF | 2 Years - 80 Years | National Institutes of Health Clinical Center (CC) | |
| Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Acute Myeloid Leukemia in Second Remission | NCT00002768 | Leukemia | filgrastim busulfan cytarabine etoposide methotrexate peripheral bloo... | 15 Years - 69 Years | Alliance for Clinical Trials in Oncology | |
| Combination Chemotherapy in Treating Patients Undergoing Surgery for Newly Diagnosed High-Grade Osteosarcoma | NCT00645632 | Sarcoma | cisplatin doxorubicin hyd... ifosfamide methotrexate adjuvant therap... neoadjuvant the... therapeutic con... | - | Mayo Clinic | |
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL | NCT03564704 | Leukemia Leukemia, Acute Adult Lymphobla... Leukemia, Lymph... Leukemia, T Cel... Adult Acute Lym... Lymphoblastic L... Lymphoblastic L... | Dexamethasone vincristine Cyclophosphamid... Idarubicin Pegaspargase Adriamycin Methotrexate 6-mercaptopurin... Etoposide Cytarabine Bone marrow asp... Intrathecal inj... Radiation thera... NGS allogeneic hema... Flow-MRD FISH Flow immunophen... Karyotyping Chidamide PET-CT scan | 14 Years - 55 Years | Nanfang Hospital, Southern Medical University | |
| Chemotherapy and Rituximab With Peripheral Stem Cell Transplantation in Treating Patients With Mantle Cell Lymphoma | NCT00020943 | Lymphoma | filgrastim rituximab carmustine cyclophosphamid... cytarabine doxorubicin hyd... etoposide leucovorin calc... methotrexate prednisone vincristine sul... peripheral bloo... | 18 Years - 69 Years | Alliance for Clinical Trials in Oncology | |
| Combination Chemotherapy With or Without Surgery & Chemoradiotherapy in Patients With Malignant Pleural Mesothelioma | NCT00354393 | Malignant Mesot... | Cisplatin Methotrexate Vinorelbine dit... Adjuvant therap... Conventional su... Neoadjuvant The... 3-dimensional c... Intensity-modul... | - 75 Years | The Cleveland Clinic | |
| S0333 Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | NCT00109837 | Leukemia | filgrastim cyclophosphamid... cytarabine daunorubicin dexamethasone doxorubicin leucovorin mercaptopurine methotrexate mitoxantrone Asparaginase prednisone thioguanine vincristine radiation thera... allopurinol bactrim | 18 Years - 64 Years | SWOG Cancer Research Network | |
| Chemotherapy, Imatinib Mesylate, and Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | NCT00039377 | Adult Acute Lym... | imatinib mesyla... methotrexate vincristine sul... leucovorin calc... peripheral bloo... autologous hema... allogeneic hema... total-body irra... tacrolimus filgrastim etoposide cyclophosphamid... cytarabine laboratory biom... | 15 Years - 59 Years | National Cancer Institute (NCI) | |
| Tagraxofusp and Low-Intensity Chemotherapy for the Treatment of CD123 Positive Relapsed or Refractory Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma | NCT05032183 | Recurrent Adult... Recurrent B Acu... Recurrent T Acu... Refractory B Ac... Refractory Lymp... Refractory T Ac... | Cyclophosphamid... Cytarabine Dexamethasone Filgrastim-sndz Leucovorin Mercaptopurine Mesna Methotrexate Pegfilgrastim Prednisone Rituximab Tagraxofusp-erz... Vincristine | 18 Years - 70 Years | M.D. Anderson Cancer Center | |
| A Study of Tocilizumab (RoActemra/Actemra) in Monotherapy or in Combination With Methotrexate or Other Non-Biologic DMARDs in Participants With Active Rheumatoid Arthritis and an Inadequate Response to Current Non-Biologic DMARD Therapy or the First Anti-TNF Biologic Agent | NCT02046603 | Rheumatoid Arth... | Tocilizumab DMARDs Oral Corticoste... Methotrexate | 18 Years - | Hoffmann-La Roche | |
| Combination Chemotherapy in Treating Patients With Lymphoma | NCT00002835 | Lymphoma | Bleomycin Sulfa... Filgrastim (G-C... Recombinant Int... Carmustine Cisplatin (CDDP... Cyclophosphamid... Cytarabine (ARA... Etoposide (VP-1... Idarubicin Ifosfamide Leucovorin Calc... Melphalan Methotrexate Methylprednisol... mitoxantrone hy... Vincristine Sul... Peripheral Bloo... Radiation Thera... | 15 Years - 59 Years | M.D. Anderson Cancer Center | |
| Dactinomycin or Methotrexate in Treating Patients With Low-Risk Gestational Trophoblastic Neoplasia | NCT01535053 | Choriocarcinoma FIGO Stage I Ge... FIGO Stage II G... FIGO Stage III ... Hydatidiform Mo... | Dactinomycin Leucovorin Calc... Methotrexate Quality-of-Life... | 18 Years - | GOG Foundation | |
| Modified Stem Cell Transplant Procedure to Treat Patients With Blood and Immune System Cancers | NCT00051311 | Hematologic Neo... | Stem cell trans... Fludarabine Cyclophosphamid... Etoposide Doxorubicin Vincristine Prednisone Methotrexate Cyclosporine Apheresis | 18 Years - 75 Years | National Institutes of Health Clinical Center (CC) | |
| Combination Chemotherapy and Inotuzumab Ozogamicin in Treating Patients With B Acute Lymphoblastic Leukemia | NCT03488225 | Acute Lymphobla... B Acute Lymphob... B Acute Lymphob... | Cyclophosphamid... Cytarabine Dexamethasone Doxorubicin Hyd... Inotuzumab Ozog... Laboratory Biom... Leucovorin Calc... Mercaptopurine Methotrexate Ofatumumab Prednisone Rituximab Vincristine Sul... | 16 Years - | M.D. Anderson Cancer Center | |
| Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia | NCT00550992 | Leukemia | anti-thymocyte ... asparaginase busulfan cyclophosphamid... cyclosporine cytarabine daunorubicin hy... etoposide leucovorin calc... melphalan mercaptopurine methotrexate mitoxantrone hy... pegaspargase prednisolone prednisone therapeutic hyd... thioguanine vincristine sul... allogeneic bone... allogeneic hema... umbilical cord ... | - 1 Year | Dutch Childhood Oncology Group |
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