Neoplasms

Digestive System Diseases

All Conditions

Behaviors and Mental Disorders

Rare Diseases

Anus Neoplasms

Rectal Neoplasms

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Intestinal Diseases

Anus Diseases

Rectal Diseases

Quality of Life

Anal Cancer

EORTC QLQ C30

EORTC QLQ CR29

Falk Roeder, MD

Sabine Gerum, MD

Franziska Walter, MD

Michael Hoffmann, MD

Observational study to evaluate longitudinal quality of life according to standardized EORTC questionaires as well as functional outcome, oncological outcome and toxicity in patients treated with definitive chemoradiation for anal cancer

Observational study to evaluate longitudinal quality of life according to standardized EORTC questionaires as well as functional outcome, oncological outcome and toxicity in patients treated with definitive chemoradiation for anal cancer. Qol will be evaluated by standardized EORTC questionaires QLQ C30 and QLQ CR29. Acute and late toxicity will be assessed according to CTCAE 4.03. Oncological outcome will be assessed with regard to local and distant control, patterns of recurrence, freedom from treatment failure and overall survival. Correlations of physicians- and patients-assessed functional outcomes are planned.

Prospective Observational Trial to Evaluate Quality of Life After Definitive Chemoradiation in Patients With Anal Cancer (LANACARE)

Quality of life measured by EORTC questionaire QLQC30 in absolute values at different time points and change over time

Quality of life measured by EORTC questionaire QLQCR29 in absolute values at different time points and change over time

absence of disease progression inside the target volume of radiation therapy

absence of disease progression outside the target volume of radiation therapy

absence of disease progression inside or outside the target volume of radiation therapy

acute toxicity caused by chemoradiation according to CTCAE 4.03

late toxicity caused by chemoradiation according to CTCAE 4.03

Ludwig-Maximilians - University of Munich

Consultant

Treatment with neoadjuvant short term radiation therapy (5x5 Gy) followed by surgery. Quality of life will be assessed using the EORTC QLQ C30 and EORTC QLQ CR 29 questionaire.

Treatment with neoadjuvant Long-term chemoradiation followed by surgery. Quality of life will be assessed using the EORTC QLQ C30 and EORTC QLQ CR 29 questionaire

Observational study to evaluate longitudinal quality of life according to standardized EORTC questionaires as well as functional Outcome, oncological outcome and toxicity in patients treated with neoadjuvant short term radiation or long-term chemoradiation followed by surgery

Observational study to evaluate longitudinal quality of life in patients treated with neoadjuvant short-course Irradiation or neoadjuvant Long-Course chemoradiation followed by surgery. QoL will be evaluated by standardized EORTC questionaires QLQ C30 and CR29. Acute and late toxicity will be assessed according to CTCAE 4.03. Oncological Outcome will be assessed with regard to local and distant Control, Patterns of recurrence, freedom from Treatment failure and Overall survival. Correlations of physicians- and Patient-assessed functional outcomes are planned.

Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer

Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer

Quality of life measured by EORTC questionaires QLQC30 in absolute values at different time points and change over time

Quality of life measured by EORTC questionaires QLQCR29 in absolute values at different time points and change over time

acute toxicity by Radiation or chemoradiation according to CTCAE 4.03

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Prospective Observational Trial to Evaluate Quality of Life After Definitive Chemoradiation in Patients With Anal Cancer (LANACARE)	NCT03792854	Anal Cancer Quality of Life Chemoradiation	EORTC QLQ C30 EORTC QLQ CR29	18 Years -	Ludwig-Maximilians - University of Munich
Prospective Observational Trial to Evaluate Quality of Life After Neoadjuvant Radiation or Chemoradiation Followed by Surgery in Patients With Rectal Cancer	NCT03731130	Rectal Cancer Quality of Life Radiation Thera... Chemoradiation	EORTC QLQ C30 EORTC QLQ CR29	18 Years -	Ludwig-Maximilians - University of Munich
Prospective Observational Trial to Evaluate Quality of Life After Definitive Chemoradiation in Patients With Anal Cancer (LANACARE)	NCT03792854	Anal Cancer Quality of Life Chemoradiation	EORTC QLQ C30 EORTC QLQ CR29	18 Years -	Ludwig-Maximilians - University of Munich

Spots Global Cancer Trial Database for eortc qlq cr29