Nutritional and Metabolic Diseases

All Conditions

Metabolic Diseases

50 subjects, adults aged over 18 years, voluntarly participating in this observational study

This is an observational study. The control group (omnivours) will be compared with all otgher groups

This is an observational study

Esther Molina Montes

Noelia M Rodriguez Martin

Mireia Obon Santacana

Pilar Amiano

Esther Molina Montes, Doctor

Esther Molina-Montes

Maria Dolores Ruiz Lopez

Reyes Artacho

Belen Garcia-Villanova

Vito Verardo

Maria Jose Sanchez Perez

Miguel Rodriguez Barranco

Beatriz Sarria

Noelia M Rodriguez-Martin

Justo J Pedroche Jimenez

Ana L Lemus-Conejo

Rocio M Toscano Sanchez

Raquel Cumeras

Noelia M Rodriguez

This projects aims to characterize dietary habits and nutrition quality of pro-vegetarian diets as compared to omnivorous diets. It also aims to stablish gut microbial and metabolit profiles of this dietary pattern, in order to elucidate the role of plant-based diets in cancer prevention and treatment.

Plant-based foods (fruits, vegetables, cereals, nuts and seeds, legumes, and vegetable oils) are the main source of fiber and other bioactive compounds in the diet. Plant-based diets are therefore assumed to prevent mortality and the ocurrence of chronic diseases including cancer. However, evidence on this issue is still scarce, and the mechanisms and drivers of their potential health benefits are also only partially known.

The main objectices of this project are:

1. To develop and validate dietary assessment methods for the vegetarian population
2. To assess dietary habits and consumer beliefs of vegetarians with respect to omnivores, considering different types of vegetarian diets
3. To identify a gut microbiota signature related to plant-based diets from subgroups of subjects following a plant-based diet foods (vegans, lacto-vegetarians, ..., and pro-vegetarians) and omnivorous subjects (non-plant-based diets), from stool metagenomic sequencing.
4. To relate this signature with metabolites present in faeces (related to the presence of certain microbial species) and in urine to improve the predictive capacity of the microbial signature of vegetable diets.
5. Validate the signature using independent study populations, and including colorectal and breast cancer survivors as another study target.

Pro-Vegetarian Diets, Microbial/Metabolite Profiles and Cancer

Characterizacion of Pro-VEgetarian Diets: Diet Quality and Nutrition, MIcrobial/Metabolite Profiles and Implications in CAncer (MIVECA Study)

Dietary habits will be taken by an online specific Food Frequency Questionnaire (FFQ) for Spanish population, including novel vegetarian foods to evaluate vegetarian food consumption. The data analysis will be taken at baseline outcome.

To validated dietary assessment method, two 24-Hour-Recalls in two non-consecutive days will be used, as well as the analysis of specific vegetarian diet metabolites in urine and stool samples using Ultra performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS). The data analysis will be taken at baseline. We have estimated that 200 subjects will be sufficient to detect, with a 95% confidence and power of 90%, correlation coefficients greater than rho=0.2.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Pro-Vegetarian Diets, Microbial/Metabolite Profiles and Cancer	NCT05621122	Dietary Habits Food Habits Nutrition, Heal... Cancer Metabolic Disea...	This is an obse...	18 Years -	Universidad de Granada
Pro-Vegetarian Diets, Microbial/Metabolite Profiles and Cancer	NCT05621122	Dietary Habits Food Habits Nutrition, Heal... Cancer Metabolic Disea...	This is an obse...	18 Years -	Universidad de Granada

Spots Global Cancer Trial Database for food habits

Every month we try and update this database with for food habits cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for food habits

Every month we try and update this database with for food habits cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for food habits cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.