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Spots is the easy way to track your skin, mole and cancer changes.

Spots Global Cancer Trial Database for hedgehog inhibitor

Every month we try and update this database with for hedgehog inhibitor cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCCNCT04155190
Recurrent Basal...
Patidegib Topic...
Patidegib Topic...
18 Years - Sol-Gel Technologies, Ltd.
A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromeNCT01546038
Acute Myeloid L...
PF-04449913
Low dose ARA-C ...
PF-04449913
Decitabine
PF-04449913
Daunorubicin
Cytarabine
PF-04449913
Daunorubicin
Cytarabine
PF-04449913
Low dose ARA-C ...
18 Years - Pfizer
An Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCCNCT04155190
Recurrent Basal...
Patidegib Topic...
Patidegib Topic...
18 Years - Sol-Gel Technologies, Ltd.
A Study To Evaluate PF-04449913 With Chemotherapy In Patients With Acute Myeloid Leukemia or Myelodysplastic SyndromeNCT01546038
Acute Myeloid L...
PF-04449913
Low dose ARA-C ...
PF-04449913
Decitabine
PF-04449913
Daunorubicin
Cytarabine
PF-04449913
Daunorubicin
Cytarabine
PF-04449913
Low dose ARA-C ...
18 Years - Pfizer
A Study Evaluating the Safety and Efficacy of ENV-101 (Taladegib) in Patients With Advanced Solid Tumors Harboring PTCH1 Loss of Function MutationsNCT05199584
Solid Tumors Wi...
ENV-101 (talade...
18 Years - Endeavor Biomedicines, Inc.
Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell CarcinomasNCT02828111
Basal Cell Carc...
Patidegib
Vehicle gel
18 Years - 85 YearsPellePharm, Inc.
Clinical Trial of Patidegib Gel 2%, 4%, and Vehicle Applied Once or Twice Daily to Decrease the GLI1 Biomarker in Sporadic Nodular Basal Cell CarcinomasNCT02828111
Basal Cell Carc...
Patidegib
Vehicle gel
18 Years - 85 YearsPellePharm, Inc.
A Study Evaluating Intensive Chemotherapy With or Without Glasdegib or Azacitidine With or Without Glasdegib In Patients With Previously Untreated Acute Myeloid LeukemiaNCT03416179
Leukemia, Myelo...
glasdegib
daunorubicin + ...
azacitidine
Placebo
Placebo
glasdegib
cytarabine
HSCT
18 Years - Pfizer
Gemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic AdenocarcinomaNCT01431794
Pancreatic Duct...
LDE225-600mg
Gemcitabine
nab-paclitaxel
LDE225-400mg
LDE225-800mg
18 Years - Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Effect on Tumor Perfusion of a Chemotherapy Combining Gemcitabine and Vismodegib Before Surgery in Pancreatic CancerNCT01713218
Pancreatic Aden...
gemcitabine
Vismodegib
Neoadjuvant che...
18 Years - Erasme University Hospital
Vismodegib Combined With Atezolizumab in Platinum Resistant Ovarian, Fallopian Tube, and Primary Peritoneal CancerNCT05538091
Platinum-Resist...
Platinum-Resist...
PARP Inhibitor
Hedgehog Inhibi...
Vismodegib
Atezolizumab
18 Years - University of Pittsburgh
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