Neoplasms

Digestive System Diseases

All Conditions

Skin and Connective Tissue Diseases

Rare Diseases

Gastrointestinal Stromal Tumors

Neoplasms, Connective Tissue

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

This is a kind of traditional surgical method.only use laparoscopy to resect the GIST.

LECS resects the GIST completely by laparoscopy with the help of the precise positioning and guidance of endoscopy.

compare to the traditional surgery to resect the tumor,we will add the endoscopy during the operation to improve the safety and effectiveness of surgery

laparoscopic and endoscopic cooperative surgery

laparoscopic surgery

Jun Jun She, M.D; PhD

Jun Jun She, M.D.;Ph.D.

Gastrointestinal stromal tumor (GIST) is a kind of mesenchymal tumor with malignant differentiation potential. It originated from mesenchymal stem cells of gastrointestinal tract.The most common is that gastric stromal tumors(GST) make up 60-70% of gastrointestinal stromal tumors.The first choice for the treatment of non-metastatic gastric stromal tumors is to ensure the integrity of the tumor and obtain the negative surgical margin.At present, the common surgical methods of resection of gastric stromal tumors include laparotomy and laparoscopy, most of them are partial gastrectomy, wedge-shaped resection, proximal subtotal gastrectomy, distal subtotal gastrectomy and total gastrectomy, etc.There was no significant difference between open surgery and laparoscopic surgery.With the rapid development of endoscopic technology in recent years, endoscopes have been continuously explored in practice.Laparoscopic endoscopic cooperative surgery(LECS) is different from the past technology. It is a new radical resection of GIST presented by Japanese scholars. LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy .This method conforms to the idea of the modern minimally invasive surgery, and avoids many problems，such as incomplete resection and disorders of digestion caused by excessive tissue resection. Investigators will observe the diffenrence of LECS and traditional laparoscopic surgeries.Firstly,the investigators will collect 80 cases of GST patients, randomly assigned for the laparoscopic group, the LECS surgical treatment. Secondly, to analyzing the basic treatment and follow-up data, including the operation time, blood loss, the number of transfer laparotomy or laparoscopy, the number of cut edge positive, the distances of cut edge away from the tumor edge, the cases of anastomotic fistula bleeding, stenosis, average such confinement, the meal time, cost of treatment, tumor recurrence rate, the presence of residual stomach, upset stomach and frequency, reflux esophagitis, bile reflux gastritis and other indicators.The purpose of this subject is to observe the effectivity and safety of LECS , invent serval LECS equipment patents and provide some references for LECS applying to the minimally invasive surgery of the digestive tract tumor and multidisciplinary treatment mode.It also provides reference for gastrointestinal stromal tumors, leiomyomas, ectopic pancreas, carcinoid, early carcinomas, giant adenomas and polyps.

Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors

Application of Laparoscopy Combined With Endoscopy Surgery in the Treatment of Gastric Stromal Tumors

record in minutes,from the beginning of anesthesia to the end

to ensure the integrity of the tumor and obtain the negative surgical margin

the time in bed to the postoperative patient

the time to eat to the postoperative patient

including anastomotic stoma fistula,anastomotic stenosis,abdominal infection,postoperative bleeding

periodic review the CT or MRI or endoscope

Air Force Military Medical University, China

First Affiliated Hospital Xi'an Jiaotong University

Laparoscopic endoscopy combined surgery. This is a kind of traditional surgical method.

LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy .

Single-arch LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy

Laparoscopic endoscopy combined surgery

Single-arch laparoscopic and endoscopic cooperative surgery

Jun Jun She, M.D.; PhD.

Gastric stromal tumor is a gastrointestinal mesenchymal tumor with malignant differentiation potential, the incidence increased year by year. The surgical resection is the primary treatment for it. Although laparoscopic GIST resection has many benefits，due to in lack of the delicate sense of touch, it could lead to the incomplete resection and disorders of digestion. More than 33% of postoperative patients have the gastric dysfunction. Laparoscopic endoscopy combined surgery is different from the past technology. It is a new radical resection of GIST presented by Japanese scholars. LECS resects the tumor completely by laparoscopy with the help of the precise positioning and guidance of endoscopy .This method conforms to the idea of the modern minimally invasive surgery, and avoids many problems，such as incomplete resection and disorders of digestion caused by excessive tissue resection. our team will spearhead the GIST treatment of LECS. First of all, the investigators will collect 120 cases of GIST patients, randomly assigned for the laparoscopic group, the LECS, single-arch the LECS surgical treatment. Secondly, to analyzing the basic treatment and follow-up data, including the operation time, blood loss, the number of transfer laparotomy, the number of cut edge positive, the distances of cut edge away from the tumor edge, the cases of anastomotic fistula bleeding, stenosis, average such confinement, the meal time, cost of treatment, tumor recurrence rate, the presence of residual stomach, upset stomach and frequency, reflux esophagitis, bile reflux gastritis and other indicators.The purpose of this subject is to observe the effectivity and safety of LECS and single-arch the LECS, invent serval LECS equipment patents and provide some references for LECS applying to the minimally invasive surgery of the digestive tract tumor and multidisciplinary treatment mode .

the Laparoscopic and Endoscopic Cooperative Surgery of Gastrointestinal Stromal Tumor

the Prospective, Randomized and Comparative Clinical Study of Laparoscopic and Endoscopic Cooperative Surgery in the Treatment of Gastrointestinal Stromal Tumor

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors	NCT03601234	Gastrointestina...	laparoscopic an... laparoscopic su...	-	First Affiliated Hospital Xi'an Jiaotong University
Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors	NCT03601234	Gastrointestina...	laparoscopic an... laparoscopic su...	-	First Affiliated Hospital Xi'an Jiaotong University
Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors	NCT03601234	Gastrointestina...	laparoscopic an... laparoscopic su...	-	First Affiliated Hospital Xi'an Jiaotong University
the Laparoscopic and Endoscopic Cooperative Surgery of Gastrointestinal Stromal Tumor	NCT02763748	Gastrointestina...	Laparoscopic en... laparoscopic an... Single-arch lap...	-	First Affiliated Hospital Xi'an Jiaotong University

Spots Global Cancer Trial Database for laparoscopic and endoscopic cooperative surgery