Spots Global Cancer Trial Database for gastrointestinal stromal tumors
Every month we try and update this database with for gastrointestinal stromal tumors cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Endoscopic Full Thickness Resection of Gastric Subepithelial Tumors (FROST) | NCT02488746 | Gastric Neoplas... Gastrointestina... | GERDX(TM) | 18 Years - | Kliniken Ludwigsburg-Bietigheim gGmbH | |
| ESTD vs. VATS for Upper Gastrointestinal Submucosal Tumors | NCT01768104 | Upper Gastroint... Gastrointestina... Leiomyoma | ESTD VATS | 15 Years - 75 Years | Nanfang Hospital, Southern Medical University | |
| Efficiency of Imatinib Treatment Maintenance or Interruption After 3 Years of Adjuvant Treatment in Patients With Gastrointestinal Stromal Tumours (GIST) | NCT02260505 | Gastrointestina... Resected Gastro... Non-metastatic High Risk of Re... KIT Gene Mutati... | Imatinib mainte... | 18 Years - | Centre Leon Berard | |
| Treatment Patterns in Gastrointestinal Stromal Tumors in the Community Oncology Setting | NCT00877045 | Gastrointestina... | 18 Years - | SCRI Development Innovations, LLC | ||
| MITIGATE-NeoBOM: A Study to Evaluate 68Ga- NeoBOMB1 in Patients With Advanced TKI-treated GIST Using PET/CT | NCT02931929 | Gastrointestina... | 68Ga-NeoBOMB1, ... | 21 Years - | Medical University Innsbruck | |
| Robotic Resection for Patients With Gastric Gastrointestinal Stromal Tumors: a Single-center Study | NCT03238820 | Gastrointestina... | Robotic gastric... | 18 Years - 80 Years | Jinling Hospital, China | |
| Efficacy and Safety of Dovitinib in Patients With Gastrointestinal Stromal Tumors Refractory and/or Intolerant to Imatinib | NCT01478373 | Gastrointestina... | Dovitinib (TKI2... | 18 Years - | Novartis | |
| Laparoscopic Resection of Large Gastric Stromal Tumors | NCT02662478 | Gastrointestina... | Laparoscopic Su... | 18 Years - | Medical Park Gaziantep Hospital | |
| Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST) | NCT00812240 | Gastrointestina... | Masitinib Imatinib | 18 Years - | AB Science | |
| A Real-world Comparison of FNB and FNA in IHC-required Lesions. | NCT05565066 | Neuroendocrine ... Autoimmune Panc... Gastrointestina... | FNB group FNA group | 18 Years - | Huazhong University of Science and Technology | |
| Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST) | NCT00782834 | Gastrointestina... | Nilotinib | 18 Years - | Fox Chase Cancer Center | |
| Liver Transplantation for Unresectable GIST Liver Metastases | NCT04825470 | Liver Diseases Liver Cancer Liver Metastase... Liver Neoplasms Liver Mass Liver Carcinoma Liver Transplan... Liver Transplan... GIST GIST, Malignant Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Metastases to L... Metastatic Live... Metastasis Metastases Liver Transplan... Transplant Onco... | Liver Transplan... | 18 Years - | Hospital Universitario Virgen de la Arrixaca | |
| Gleevec Administered Preoperatively to Reduce Gastrointestinal Stromal Tumor (GIST) | NCT00290485 | Gastrointestina... | Imatinib mesyla... | 18 Years - | Maisonneuve-Rosemont Hospital | |
| DNX-2440 for Resectable Colorectal Liver Metastasis | NCT04714983 | Liver Metastase... Liver Metastasi... Colorectal Canc... Breast Cancer Gastric Cancer Periampullary C... Melanoma Renal Cell Canc... Sarcoma Squamous Cell C... Gastrointestina... | DNX-2440 | 18 Years - | DNAtrix, Inc. | |
| Safety and Efficacy of Avapritinib in Chinese Patients With Gastrointestinal Stromal Tumor (GIST) in the Real World | NCT05381753 | Gastrointestina... | Avapritinib Tyrosine kinase... | 18 Years - | CStone Pharmaceuticals | |
| A Safety, Tolerability and PK Study of DCC-2618 in Patients With Advanced Malignancies | NCT02571036 | Gastrointestina... Advanced System... Advanced Cancer... | DCC-2618 DCC-2618 | 18 Years - | Deciphera Pharmaceuticals LLC | |
| A Drug-drug Interaction Study of Avapritinib and Midazolam | NCT04908176 | Gastrointestina... GIST Non-resectable ... Recurrent or Un... | Avapritinib midazolam | 18 Years - | Blueprint Medicines Corporation | |
| Preoperative and Postoperative Imatinib Mesylate Study in Patients With c-Kit Positive GIST | NCT00500188 | Gastrointestina... | Imatinib Mesyla... | - | M.D. Anderson Cancer Center | |
| Dovitinib for Imatinib/Sumitinib-failed Gastrointestinal Stromal Tumors (GIST): TKI258 | NCT01440959 | Gastrointestina... | dovitinib | 20 Years - | Asan Medical Center | |
| Study of AMN107 With Imatinib in Gastrointestinal Stromal Tumors (GIST) | NCT00135005 | Gastrointestina... | AMN107, STI571 | 18 Years - | Novartis | |
| The Oncopanel Pilot (TOP) Study | NCT02171286 | Colorectal Canc... Advanced Non-Sm... Advanced Melano... Gastrointestina... Patients With D... | 18 Years - | British Columbia Cancer Agency | ||
| Liver Transplantation for Unresectable GIST Liver Metastases | NCT04825470 | Liver Diseases Liver Cancer Liver Metastase... Liver Neoplasms Liver Mass Liver Carcinoma Liver Transplan... Liver Transplan... GIST GIST, Malignant Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Gastrointestina... Metastases to L... Metastatic Live... Metastasis Metastases Liver Transplan... Transplant Onco... | Liver Transplan... | 18 Years - | Hospital Universitario Virgen de la Arrixaca | |
| Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors | NCT01381822 | Advanced Renal ... Gastrointestina... Pancreatic Neur... | TH-302 | 18 Years - | Threshold Pharmaceuticals | |
| Regorafenib Post-marketing Surveillance in Japan | NCT01933958 | Gastrointestina... | Regorafenib (St... | - | Bayer | |
| Phase II Clinical Study of Imatinib Mesylate in Patients With Malignant Gastrointestinal Stromal Tumors (Extension Study) | NCT00237172 | Gastrointestina... | Imatinib Mesyla... | 20 Years - 74 Years | Novartis | |
| A Study of BBI503 in Adult Patients With Advanced Gastrointestinal Stromal Tumors | NCT02232620 | Gastrointestina... | BBI503 | 18 Years - | Sumitomo Pharma America, Inc. | |
| A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib | NCT03673501 | Gastrointestina... | Ripretinib Sunitinib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Imatinib TDM in GIST | NCT05493215 | Gastrointestina... | Imatinib | 18 Years - | University of Kentucky | |
| Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring | NCT05500391 | Stage I Testicu... Stage I Testicu... Gastrointestina... Ovarian Germ Ce... Adenocarcinoma,... Borderline Ovar... Sex Cord-Stroma... Mucinous Adenoc... Carcinoma, Smal... Carcinosarcoma,... Serous Tumor of... Glioma Neuroendocrine ... Aggressive Fibr... | Oncological Fol... | 18 Years - | Centre Oscar Lambret | |
| Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors | NCT03601234 | Gastrointestina... | laparoscopic an... laparoscopic su... | - | First Affiliated Hospital Xi'an Jiaotong University | |
| GIST Oral Paclitaxel(Liporaxel) | NCT06326346 | Gastrointestina... | Liporaxel | 20 Years - | Asan Medical Center | |
| A Study of Ripretinib vs Sunitinib in Advanced GIST Patients After Treatment With Imatinib | NCT03673501 | Gastrointestina... | Ripretinib Sunitinib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) Patients | NCT01031628 | Gastrointestina... | Imatinib mesyla... Imatinib mesyla... Imatinib mesyla... | 18 Years - | Sarcoma Alliance for Research through Collaboration | |
| SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST | NCT06208748 | Gastrointestina... GIST | Bezuclastinib i... | 18 Years - | Sarcoma Alliance for Research through Collaboration | |
| A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib | NCT05734105 | GIST | Ripretinib Sunitinib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Regorafenib in Subjects With Gastrointestinal Stromal Tumors (GIST) Who Have Progressed After Standard Therapy | NCT01646593 | Gastrointestina... | Regorafenib (BA... | 18 Years - | Bayer | |
| Paclitaxel in Patients With Metastatic or Advanced Gastrointestinal Stromal Tumors (GIST) After Failure to Imatinib and Sunitinib | NCT02607332 | Gastrointestina... | Paclitaxel | 20 Years - | Asan Medical Center | |
| Laparoscopic Endoscopic Cooperative Surgery in the Treatment of Gastric Stromal Tumors | NCT03601234 | Gastrointestina... | laparoscopic an... laparoscopic su... | - | First Affiliated Hospital Xi'an Jiaotong University | |
| A Retrospective Clinical Records Review of Patients Diagnosed With Gastrointestinal Stromal Tumour at Two Tertiary Institutes in Singapore | NCT00718211 | Gastrointestina... | - | National University Hospital, Singapore | ||
| EUS-FNB vs. Single-incision Needle-knife (SINK) Biopsy for Gastrointestinal SELs | NCT02866045 | Disorder of Upp... Gastrointestina... Gastrointestina... | EUS-guided fine... Single incision... | 18 Years - | Unity Health Toronto | |
| Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK | NCT04181970 | Soft-tissue Sar... Gastrointestina... Bone Sarcoma | Quality assessm... | 18 Years - 120 Years | Grupo Espanol de Investigacion en Sarcomas | |
| A Study of CS3007 in Subjects With Gastrointestinal Stromal Tumor | NCT04254939 | Gastrointestina... | CS3007 (BLU-285... | 18 Years - | CStone Pharmaceuticals | |
| A Bioequivalence Study of Sunitinib Malate Capsules. | NCT05800106 | Gastrointestina... Renal Cell Carc... Pancreatic Neur... | Sunitinib malat... Sunitinib malat... | 18 Years - 45 Years | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | |
| The Effects of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib | NCT02800330 | Colorectal Neop... Gastrointestina... | Esomeprazole 40... Esomeprazole 40... Regorafenib 160... | 18 Years - | Erasmus Medical Center | |
| Detection of CF-DNA in Patients With Gastrointestinal Stromal Tumors (GIST) | NCT01462994 | Gastrointestina... | Blood will be w... | 18 Years - | Technical University of Munich | |
| A Phase I/II Study of Sunitinib Malate (SU011248) In Patients With Gastrointestinal Stromal Tumor (GIST) | NCT00457743 | Gastrointestina... | Sunitinib malat... | 20 Years - 75 Years | Pfizer | |
| CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors | NCT02401815 | Gastrointestina... | PLX9486 Pexidartinib Sunitinib | 18 Years - | Cogent Biosciences, Inc. | |
| A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors | NCT05464875 | Gastrointestina... Unresectable So... Recurrent Metas... | 18 Years - | First Affiliated Hospital, Sun Yat-Sen University | ||
| Current Management of Gastrointestinal Stromal Tumors (GIST) in the Region of Coquimbo | NCT00564265 | Gastrointestina... | Observation | 15 Years - | Cirujanos la Serena | |
| Phase 1 Study of OSI-930 in Cancer Patients | NCT00513851 | Advanced Solid ... | OSI-930 OSI-930 | 18 Years - | Astellas Pharma Inc | |
| Paclitaxel in Patients With GIST With Low P-glycoprotein Expression After Failure of at Least Imatinib and Sunitinib, and Regorafenib. | NCT03944304 | Gastrointestina... | Paclitaxel | 20 Years - | Asan Medical Center | |
| A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies | NCT05957367 | Colorectal Canc... GIST | DCC-3116 Ripretinib Cetuximab Encorafenib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics | NCT04584008 | Biliary Tract N... Gastric Cancer Esophageal Squa... Colorectal Canc... Gastrointestina... Pancreatic Canc... Neuroendocrine ... Unknown Primary... Digestive Cance... | FGFR Inhibitor,... Other Therapy | 18 Years - | Peking University | |
| Second-line Pharmacotherapy Patterns and Outcomes of Advanced Gastrointestinal Stromal Tumor: A Real-world Study | NCT05440357 | Gastrointestina... | 18 Years - | First Affiliated Hospital, Sun Yat-Sen University | ||
| Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib | NCT04409223 | Gastrointestina... | Famitinib capsu... Sunitinib Capsu... | 18 Years - | Jiangsu HengRui Medicine Co., Ltd. | |
| Special Investigation For Gist Of Sunitinib Malate (Regulatory Post Marketing Commitment Plan). | NCT00716820 | Gastrointestina... | SUNITINIB MALAT... | 17 Years - | Pfizer | |
| The Oncopanel Pilot (TOP) Study | NCT02171286 | Colorectal Canc... Advanced Non-Sm... Advanced Melano... Gastrointestina... Patients With D... | 18 Years - | British Columbia Cancer Agency | ||
| A Multicenter Study of Avapritinib Efficacy and Safety of Metastatic or Unresectable Gastrointestinal Stromal Tumors | NCT05464875 | Gastrointestina... Unresectable So... Recurrent Metas... | 18 Years - | First Affiliated Hospital, Sun Yat-Sen University | ||
| Sorafenib for Imatinib/Sunitinib-failed GIST | NCT01091207 | Gastrointestina... | Sorafenib | 18 Years - | Samsung Medical Center | |
| Dose-Escalation Study of TH-302 in Combination With Sunitinib to Treat Patients With Advanced Renal Cell Carcinoma,Gastrointestinal Stromal Tumors and Pancreatic Neuroendocrine Tumors | NCT01381822 | Advanced Renal ... Gastrointestina... Pancreatic Neur... | TH-302 | 18 Years - | Threshold Pharmaceuticals | |
| Five Year Adjuvant Imatinib Mesylate (Gleevec®) in Gastrointestinal Stromal Tumor (GIST) | NCT00867113 | Gastrointestina... | imatinib mesyla... | 18 Years - | Novartis | |
| Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics | NCT04584008 | Biliary Tract N... Gastric Cancer Esophageal Squa... Colorectal Canc... Gastrointestina... Pancreatic Canc... Neuroendocrine ... Unknown Primary... Digestive Cance... | FGFR Inhibitor,... Other Therapy | 18 Years - | Peking University | |
| Nilotinib Roll-over Protocol for Patients in Novartis-sponsored Nilotinib Study and Benefiting From Nilotinib Treatment | NCT01863745 | Gastrointestina... | nilotinib | 18 Years - | Novartis | |
| MITIGATE-NeoBOM: A Study to Evaluate 68Ga- NeoBOMB1 in Patients With Advanced TKI-treated GIST Using PET/CT | NCT02931929 | Gastrointestina... | 68Ga-NeoBOMB1, ... | 21 Years - | Medical University Innsbruck | |
| A Study of DCC-3116 in Combination With Anticancer Therapies in Participants With Advanced Malignancies | NCT05957367 | GIST | DCC-3116 Ripretinib | 18 Years - | Deciphera Pharmaceuticals LLC | |
| Study of Dose Escalation Versus no Dose Escalation of Imatinib in Metastatic Gastrointestinal Stromal Tumors (GIST) Patients | NCT01031628 | Gastrointestina... | Imatinib mesyla... Imatinib mesyla... Imatinib mesyla... | 18 Years - | Sarcoma Alliance for Research through Collaboration | |
| A Study of Sunitinib In Young Patients With Advanced Gastrointestinal Stromal Tumor | NCT01396148 | Gastrointestina... | sunitinib malat... sunitinib malat... | 6 Years - 20 Years | Pfizer | |
| Clinical Evaluation of Genetron D842V PCR Kit in GIST Patients | NCT05400018 | GIST Gastrointestina... | - | Genetron Health | ||
| A Retrospective Pharmacokinetics and Pharmacogenomics Research of Imatinib in Gastrointestinal Stromal Tumor Treatment | NCT03092128 | Gastrointestina... Germline Mutati... Somatic Mutatio... Plasma Concentr... | 18 Years - 80 Years | Sun Yat-sen University | ||
| Ripretinib Used for Resectable Metastatic GIST After Failure of Imatinib Therapy | NCT05132738 | Gastrointestina... | Ripretinib trea... | 18 Years - 75 Years | RenJi Hospital | |
| Efficacy of Nilotinib in Adult Patients With Gastrointestinal Stromal Tumors Resistant to Imatinib and Sunitinib. | NCT01289028 | Gastrointestina... | Nilotinib | 18 Years - | Novartis | |
| MITIGATE-NeoBOM: A Study to Evaluate 68Ga- NeoBOMB1 in Patients With Advanced TKI-treated GIST Using PET/CT | NCT02931929 | Gastrointestina... | 68Ga-NeoBOMB1, ... | 21 Years - | Medical University Innsbruck | |
| Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST) | NCT00782834 | Gastrointestina... | Nilotinib | 18 Years - | Fox Chase Cancer Center | |
| Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib | NCT04409223 | Gastrointestina... | Famitinib capsu... Sunitinib Capsu... | 18 Years - | Jiangsu HengRui Medicine Co., Ltd. | |
| A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST) | NCT04282980 | Gastrointestina... | DCC-2618 | 18 Years - | Zai Lab (Hong Kong), Ltd. | |
| Imatinib Dose Escalation to 800 mg/Day in Korean Patients With Metastatic or Unresectable GIST Harboring KIT Exon 9 Mutation: KENEDI | NCT01541709 | Gastrointestina... | imatinib | 18 Years - | Asan Medical Center | |
| A Retrospective Pharmacokinetics and Pharmacogenomics Research of Imatinib in Gastrointestinal Stromal Tumor Treatment | NCT03092128 | Gastrointestina... Germline Mutati... Somatic Mutatio... Plasma Concentr... | 18 Years - 80 Years | Sun Yat-sen University | ||
| Masitinib in First Line Treatment of Gastro-Intestinal Stromal Tumor (GIST) | NCT00812240 | Gastrointestina... | Masitinib Imatinib | 18 Years - | AB Science | |
| The Correlation Between Ripretinib Exposure and the Efficacy and Safety in Patients With Advanced GISTs | NCT06431451 | Gastrointestina... | 18 Years - | First Affiliated Hospital, Sun Yat-Sen University | ||
| Efficacy and Safety of Anlotinib in Patients With Advanced Gastrointestinal Stromal Tumor After Failure of Imatinib: a Prospective, Single Arm and Multicenter Trial | NCT04106024 | Gastrointestina... | Anlotinib | 18 Years - | Cttq |
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