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Kidney Diseases, Cystic

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participants are with endophytic renal cyst and undergo laparoscopic deroofing.2 day before laparoscopic deroofing, they were given intravenous 100 g of amino acids supplementation.

participants are with exophytic renal cyst and undergo laparoscopic deroofing.2 day before laparoscopic deroofing, they were given intravenous 100 g of amino acids supplementation.

The classic treatment of patients with simple renal cysts is deroofing, which can be performed by open surgery or laparoscopy. Laparoscopic deroofing is an effective minimally invasive approach and has gained popularity.

Laparoscopic deroofing

intravenous supplementation with 100 g of amino acids 2 day before laparoscopic deroofing.

100 g of amino acids supplementation

Zhenhua Shang, MD.

Hao Yan, MD.

Tongwen Ou, MD.

Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.

Simple renal cysts (SRC) are the most frequent type of cystic renal disease. The prevalence rate of SRCs is about 10% and increases with age. Hypertension and decreased renal functions have been reported to occur more commonly among these patients with SRC and there are no clear guidelines for managing asymptomatic SRCs.Renal functional reserve (RFR) describes the capacity of the intact nephron mass to increase glomerular filtration rate(GFR) from baseline in response to stimuli (e.g., protein load).The investigators hypothesized that RFR may be improved in some patients with simple renal cysts after laparoscopic deroofing despite identical resting glomerular filtration rate (rGFR).The aim of this study is to examine whether there is improvement of RFR in patients with simple renal cysts after laparoscopic deroofing.

Participants are assigned to two groups.One group participants are with endophytic simple renal cysts, and the other are with exophytic simple renal cysts.

Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing

Measurement of Renal Functional Reserve Change In Patients With Simple Renal Cysts Before and After Laparoscopic Deroofing

1 month after surgery, repeated glomerular filtration rate measurements are to be performed to calculate change in renal functional reserve.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing	NCT03259594	Simple Renal Cy...	Laparoscopic de... 100 g of amino ...	18 Years - 90 Years	Xuanwu Hospital, Beijing
Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing	NCT03259594	Simple Renal Cy...	Laparoscopic de... 100 g of amino ...	18 Years - 90 Years	Xuanwu Hospital, Beijing

Spots Global Cancer Trial Database for laparoscopic deroofing