Spots Global Cancer Trial Database for Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing

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Trial Identification

Brief Title: Measurement of Renal Functional Reserve Change In Patients With SRC Before and After Laparoscopic Deroofing

Official Title: Measurement of Renal Functional Reserve Change In Patients With Simple Renal Cysts Before and After Laparoscopic Deroofing

Study ID: NCT03259594

Conditions

Simple Renal Cyst

Interventions

Laparoscopic deroofing

100 g of amino acids supplementation

Study Description

Brief Summary: Renal functional reserve may be improved in patients with simple renal cysts after laparoscopic deroofing.

Detailed Description: Simple renal cysts (SRC) are the most frequent type of cystic renal disease. The prevalence rate of SRCs is about 10% and increases with age. Hypertension and decreased renal functions have been reported to occur more commonly among these patients with SRC and there are no clear guidelines for managing asymptomatic SRCs.Renal functional reserve (RFR) describes the capacity of the intact nephron mass to increase glomerular filtration rate(GFR) from baseline in response to stimuli (e.g., protein load).The investigators hypothesized that RFR may be improved in some patients with simple renal cysts after laparoscopic deroofing despite identical resting glomerular filtration rate (rGFR).The aim of this study is to examine whether there is improvement of RFR in patients with simple renal cysts after laparoscopic deroofing.