Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Symptoms and General Pathology

Eye Diseases

Rare Diseases

Melanoma

Cicatrix

Uveal Neoplasms

Neuroendocrine Tumors

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Nerve Tissue

Nevus, Pigmented

Nevus

Nevi and Melanomas

Skin Neoplasms

Skin Diseases

Eye Neoplasms

Uveal Diseases

Intraocular Melanoma

Neuroendocrine Tumor

Neuroepithelioma

endoresection of the tumor scar or, when surgery is not possible, transpupillary thermotherapy on the tumor scar

Endoresection

Transpupillary thermotherapy by laser diode on the tumor scar

Laser diode

Nathalie CASSOUX, MD, PhD

Study the efficacy of endoresection of the tumor scar or, when surgery is not possible, transpupillary thermotherapy on the tumor scar to prevent neovascular glaucoma and secondary enucleation

Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)

Phase II Evaluating Endoresection of the Tumor Scar or Transpupillary Thermotherapy When Endoresection is Not Feasible After Proton Beam Therapy for the Treatment of Large Uveal Melanomas

observed complications are : Number of glaucomas, numbrer of retinal detachment and number of secondary enucleations.

Institut Curie

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Polyps

Uterine Neoplasms

Pathological Conditions, Anatomical

Genital Neoplasms, Female

Urogenital Neoplasms

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Central Nervous System Depressants

All Drugs and Chemicals

Anesthetics

application of the laser diode by hysteroscopy to remove the endometrial polyp

application of the bipolar electrode Versapoint by hysteroscopy to remove the endometrial polyp

resection of endometrial polyps by hysteroscopy without anesthesia

polyps resection with Laser Diode

polyps resection with bipolar electrode

José Eduardo Arjona Berral, Gynecologist

Maria Dolores Lara, Gynecologist

Rafaela Dios Palomares, Engineer

Hysteroscopy today is considered the gold standard for the diagnosis and treatment of endometrial polyps. In recent years we have used the bipolar energy for resection of polyps by hysteroscopy, becoming a routine clinical practice and universally accepted.

Resection of endometrial polyps laser energy has recently begun to be used with satisfactory results, so studies are needed to analyze these results and compare it with the usual techniques .

This time in advance of medicine, it is appropriate to introduce minimally invasive procedures , allowing resection of endometrial polyps on an outpatient basis without anesthesia and acceptable to most patients.

These procedures assume a lower cost and are associated with a lower surgical risk due to their realization without anesthesia .

Hypothesis: Resection of polyps outpatient laser diode has a similar or superior to that of the bipolar electrode tolerability. The diode laser is a viable , quick , simple technique with a high percentage of resection and high degree of satisfaction of patients

Main objective: To assess the tolerability of diode laser in the treatment of endometrial polyps using a visual analogue pain scale.

Secondary objectives:

* Determine if complete resection of polyps is achieved with both methods.
* Compare the time spent on the removal of the polyp in each of the hysteroscopic methods.
* To evaluate the safety of the laser diode with respect to the bipolar electrode (vagal syndrome, uterine perforation, infection, bleeding).
* Assess the recurrence of polyps after 3 months of resection (via hysteroscopy).
* Compare the degree of patient satisfaction with the different methods.

Design: randomized single blind clinical trial corresponds to an experimental analytical study. The patients randomly into 2 groups will include: Group A bipolar electrode treatment Versapoint and Group B diode laser treatment. Randomization was performed using a random table with 2 groups, generated in Microsoft Office Excel. The sample size needed to detect a difference in visual analog pain scale of a point with respect to the laser diode bipolar electrode is calculated; assuming a standard deviation of 1.75, a sample size of 49 patients in each group (98 would be needed in total), to a level of significance of 5% (0.05 α) with a power of 0.80 (beta 0.20). Assuming a loss of individuals from 5 to 10%

Comparative Study of Endometrial Polypectomy Performed With Bipolar Electrode Versapoint and Laser Diode. A Randomised Controlled Trial.

Hospital Universitario Reina Sofia de Cordoba

Universidad Nacional de Córdoba

Isabel Bejerano Blázquez

IMIBIC

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)	NCT02874040	Uveal Melanoma Melanoma, Uveal	Endoresection Laser diode	18 Years -	Institut Curie
Comparative Study of Endometrial Polypectomy Performed With Bipolar Electrode Versapoint and Laser Diode. A Randomised Controlled Trial.	NCT02126397	Endometrial Pol...	polyps resectio... polyps resectio...	18 Years -	Maimónides Biomedical Research Institute of Córdoba
Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)	NCT02874040	Uveal Melanoma Melanoma, Uveal	Endoresection Laser diode	18 Years -	Institut Curie
Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)	NCT02874040	Uveal Melanoma Melanoma, Uveal	Endoresection Laser diode	18 Years -	Institut Curie

Spots Global Cancer Trial Database for laser diode

Every month we try and update this database with for laser diode cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for laser diode

Every month we try and update this database with for laser diode cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for laser diode cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.