Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Behaviors and Mental Disorders

Symptoms and General Pathology

Rare Diseases

Lung Neoplasms

Carcinoma, Non-Small-Cell Lung

Anxiety Disorders

Neoplasm Metastasis

Small Cell Lung Carcinoma

Head and Neck Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

Mental Disorders

Psychotic Disorders

Small Cell Lung Cancer

Medical chart review

Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory

management of therapy complications

Structured Clinical Interview for the Diagnostic and Statistical Manual-IV SCID

Functional Assessment of Cancer Therapy-General (FACT-G)

Kirsten Haman, PhD

RATIONALE: Patients who undergo treatment for head and neck cancer may become anxious and avoid contact with other people. Learning how cancer treatment may cause anxiety in patients with head and neck cancer may help improve the quality of life in these patients.

PURPOSE: This clinical trial is studying anxiety and avoidance of others in patients previously treated for head and neck cancer.

OBJECTIVES:

* Determine the relationship between treatment-provoked social anxiety and avoidance in patients previously treated for head and neck cancer.
* Determine the relationship between pre-cancer psychiatric diagnosis and post-treatment social anxiety and avoidance in these patients.
* Determine the effect of social anxiety and/or avoidance on the quality of life of these patients.
* Investigate the specificity of these relationships in patients with head and neck cancer by comparing patients with head and neck cancer to patients with lung cancer.

OUTLINE: This is a cross-sectional study. Patients are stratified according to prior treatment type (significantly impairing \[surgery\] vs less impairing \[chemotherapy/radiotherapy\]).

Patients undergo a face-to-face interview with a mental health clinician over 2 hours. Patients complete multiple psychiatric/psychological assessments during the interview, including the Structured Clinical Interview for DSM-IV (SCID); the Liebowitz Social Anxiety Scale (SAS); the Performance Status Scale for Head and Neck Cancer Patients (PSS-HN); the Social Phobia and Anxiety Inventory (SPAI); the State-Trait Anxiety Inventory (STAI); Response to Stress Questionnaire, Cancer Version (RSQ-CV); the Functional Assessment of Cancer Therapy (FACT-HNC (head neck cancer) or LC); the Voice Handicap Index (VHI); and the Body Image Scale (BIS).

Cancer treatment and medical history information are gathered from patients' medical records.

Study of Anxiety and Avoidance of Others in Patients Previously Treated for Head and Neck Cancer

Social Anxiety and Avoidance in Head and Neck Cancer Patients

Measured by the Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory, containing 24 items with each item separately rated for fear as 0 (none), 1 (mild), 2 (moderate) to 3 (severe)and for avoidance behavior as 0 (never), 1 (occasionally), 2 (often), to 3 (usually). Scores are summed with lower values indicating lower levels of social anxiety and avoidance.

Assessed using the Structured Clinical Interview for the Diagnostic and Statistical Manual-IV SCID lifetime diagnostic status (pre-cancer diagnosis) and related to the outcome for social anxiety measures. The SCID does not involve a specific scoring of responses. Trained interviewers ask questions that may involve yes/no answers or more detailed explanations. They make their diagnoses based on their experience and training. For this outcome, interviews results will be compared to and contrasted with scores on the Liebowitz Social Anxiety Scale and Social Phobia and Anxiety Inventory.

Each patient is scored on the Functional Assessment of Cancer Therapy-General (FACT-G) with 4 related sub-scales (physical, social/family, emotional, functional well-being. To generate sub-scale scores, physical and emotional items are reverse coded and items are then summed, such that higher values indicate better quality of life. Thus, each sub-scale score ranges from 0 (not at all, worse outcome) to 4 (very much, better outcome) with a minimum total score of 0 (worst quality of life) to a maximum of 16 (good quality of life).

Measured by the Liebowitz Social Anxiety Scale and the Social Phobia and Anxiety Inventory, containing 24 items with each item separately rated for fear as 0 (none), 1 (mild), 2 (moderate) to 3 (severe)and for avoidance behavior as 0 (never), 1 (occasionally), 2 (often), to 3 (usually). Scores are summed with lower values indicating lower levels of social anxiety and avoidance. Scores in study participants will be compared to scores in studies of social anxiety and avoidance in lung cancer patients

National Cancer Institute (NCI)

Vanderbilt-Ingram Cancer Center

Research Assistant Professor; Psychologist

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Study of Anxiety and Avoidance of Others in Patients Previously Treated for Head and Neck Cancer	NCT00483639	Anxiety Disorde... Head and Neck C... Lung Cancer	Medical chart r... Liebowitz Socia... management of t... Structured Clin... Functional Asse...	21 Years - 70 Years	Vanderbilt-Ingram Cancer Center
Study of Anxiety and Avoidance of Others in Patients Previously Treated for Head and Neck Cancer	NCT00483639	Anxiety Disorde... Head and Neck C... Lung Cancer	Medical chart r... Liebowitz Socia... management of t... Structured Clin... Functional Asse...	21 Years - 70 Years	Vanderbilt-Ingram Cancer Center

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