Neoplasms

All Conditions

Digestive System Diseases

Adenoma

Colorectal Neoplasms

Gastrointestinal Diseases

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Intervention: Procedure : Implementation of routine Advanced Notification Letter included in Standard Invitation procedure

Advanced Notification Letter will be implemented in invitation procedure and send two weeks before Standard Invitation (Standard Invitation will be send six weeks before planned screening colonoscopy)

Intervention: Behavioral : No included Advanced Notification Letter Sending Standard Invitation six weeks before planned screening colonoscopy

Advance Notification Letter will be send two weeks before Standard Invitation for screening colonoscopy

Implementation of ANL

Sending Standard Invitation only six weeks before planned screening colonoscopy

No included ANL

Karolina Janikowska, MD, MSc

Karolina Janikowska, MD,MSc

Jaroslaw Regula, MD, PhD

Bartlomiej Kocot

Participation in a primary screening colonoscopy programs remains low. Advanced notification letter has been shown to increase participation in colorectal cancer screening with fecal occult blood testing and to be cost effective compared to standard invitation. It is unknown whether advanced notification letter increases participation rate in primary colonoscopy screening program.

We hypothesize that an Advance Notification Letter will have significant influence on participation in screening colonoscopy, comparing to standard invitation procedure and will thus result in higher efficiency of the program.

This randomized controlled study aims to compare the participation rate in screening colonoscopy in response to advanced notification plus standard invitation letter and standard invitation letter alone.

Material and methods: 6800 individuals aged 55-64 years will be drawn from the Population Registry and randomly assigned in a 1:1 ratio to the group invited for screening colonoscopy with advanced notification letter (send two weeks before standard invitation) plus standard invitation (send six weeks before planned screening colonoscopy) or to standard invitation only (send six weeks before planned screening colonoscopy). The sample size was calculated to detect 3% difference in participation rate between the groups (25% vs 28%) with 80% power.

Effect of an Advanced Notification Letter on Screening Colonoscopy Participation

Participation in Screening Colonoscopy in Response to an Advanced Notification Letter Plus Standard Invitation Versus Standard Invitation Only - a Population-based Randomized Controlled Trial

Total cost of including Advanced notification letter into the standard invitation procedure of this study group.

A percentage of invitees who undergo the screening colonoscopy. The sample size was calculated to detect 3% difference in participation rate between the groups (25% vs 28%) with 80% power.

Estimation of the invitees' response rate to Standard Invitation and Advanced Notification Letter followed by Standard Invitation, before receiving Reminding Letter.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Effect of an Advanced Notification Letter on Screening Colonoscopy Participation	NCT02188927	Colorectal Canc... Adenoma Rectal Cancer	Implementation ... No included ANL	55 Years - 64 Years	Maria Sklodowska-Curie National Research Institute of Oncology
Effect of an Advanced Notification Letter on Screening Colonoscopy Participation	NCT02188927	Colorectal Canc... Adenoma Rectal Cancer	Implementation ... No included ANL	55 Years - 64 Years	Maria Sklodowska-Curie National Research Institute of Oncology

Spots Global Cancer Trial Database for no included anl