Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Lung Neoplasms

Multiple Pulmonary Nodules

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

The bronchovideoscope will be used together with an assisted image-guided bronchoscopic navigation software system called LungPoint®, to view lungs in a real time 3D manner.

Olympus Ultrathin Bronchofibervideoscope (XP260F)

Pyng Lee, MD

The study aims to determine if there are defining EBUS and confocal endoscopy features as well as exhaled alveolar gas VOC that can discriminate malignant pulmonary nodules or masses from benign etiology, thereby obviating unnecessary thoracotomy. Directly sampled alveolar gas VOC from patients with lung cancer will be compared against exhaled breath VOC for signature compounds that may complement CT in screening the population at risk.

AIMS

1. To improve diagnostic yield of pulmonary nodule or mass by using combined approach of navigation bronchoscopy and EBUS.
2. To determine if characteristic features of EBUS and confocal microendoscopy exist as well as VOC patterns in alveolar and exhaled gas that can aid in discriminating malignant pulmonary nodule or mass from benign etiology by correlating with pathology.
3. To identify VOC patterns specific for lung cancer by correlating VOC from directly sampled alveolar gas and exhaled breath with pathology. Exhaled breath VOC signature may complement CT in screening population at risk.

Evaluating the Pulmonary Nodule With Imaging and Biomarkers

National University Hospital, Singapore

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Evaluating the Pulmonary Nodule With Imaging and Biomarkers	NCT01739881	Lung Cancer	Olympus Ultrath...	21 Years -	National University Hospital, Singapore
Evaluating the Pulmonary Nodule With Imaging and Biomarkers	NCT01739881	Lung Cancer	Olympus Ultrath...	21 Years -	National University Hospital, Singapore

Spots Global Cancer Trial Database for olympus ultrathin bronchofibervideoscope (xp260f)