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Ropivacaine

Anesthetics

Anesthetics, Local

Ropivacaine administration by local per and post surgery infiltration

Administration of physiological serum by local per and post surgery infiltration

40 ml infiltration at the end of the hepatectomy and then continuous local infiltration of 8 ml per hour over the 4 days after the hepatectomy

Physiological serum

Véronique Peres-Bachelot, MD

The purpose of the study is to evaluate the efficacy and impact on morphine consumption of ropivacaine administered by local per and post hepatic surgery infiltration.

Patients will be randomized to either ropivacaine or physiological serum, with equivalent administration modalities in both arms.

Patients will be followed during 4 days after the surgery. They will also come back for a follow-up visit one month later.

It is necessary to enrol 100 patients. The estimated period of inclusion is 24 months.

This is a prospective, comparative, monocentric, double-blind randomized study.

Placebo-controlled Evaluation of Ropivacaine Efficacy by Local Infiltrations

A Double-blind Placebo-controlled Evaluation of Ropivacaine Efficacy by Local Per and Post Hepatectomy Infiltrations for Adult Pain Management

AstraZeneca

Fondation Apicil

Centre Leon Berard

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Placebo-controlled Evaluation of Ropivacaine Efficacy by Local Infiltrations	NCT01194843	Hepatectomy Pain Metastasis	Ropivacaine Physiological s...	18 Years -	Centre Leon Berard
Placebo-controlled Evaluation of Ropivacaine Efficacy by Local Infiltrations	NCT01194843	Hepatectomy Pain Metastasis	Ropivacaine Physiological s...	18 Years -	Centre Leon Berard

Spots Global Cancer Trial Database for physiological serum