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patients will do elective open colonic mass resection and anastomosis will receive Infusion of 6 ml/kg/hr. Ringer's solution.

patients will do elective open colonic mass resection and anastomosis. Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.

Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.

pulse pressure variation

Infusion of 6 ml/kg/hr. Ringer's solution.

conventional fluid management

pulse pressure variation based intraoperative fluid therapy versus traditional fluid therapy for colonic cancer patients undergoing mass resection and anastomosis for maintaining adequate hydration without complications.

All Patients will be assigned randomly by using computerized program to one of the two equal groups. Patients will be (forty five patients per group):

Group A ;( control group) Forty five patients will do elective open colonic mass resection and anastomosis. Infusion of 6 ml/kg/hr. Ringer's solution.

Group B; Forty five patients will do elective open colonic mass resection and anastomosis. Infusion of 2 ml/kg/hr. Ringer's solution guided by pulse pressure variation.

Intraoperative fluid volume, hemodynamics, serum lactate and intestinal edema will be measured after induction of anesthesia and every hour till the end of the operation, length of the hospital stay, first time to gastrointestinal motion and postoperative complications are recorded.

participant eligibility is based on self-representation of gender identity

Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis	NCT05502835	Intraoperative ... Hemodynamics Serum Lactate Intestinal Edem... Length of the H... First Time to G... Postoperative C...	pulse pressure ... conventional fl...	18 Years - 70 Years	Ain Shams University
Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis	NCT05502835	Intraoperative ... Hemodynamics Serum Lactate Intestinal Edem... Length of the H... First Time to G... Postoperative C...	pulse pressure ... conventional fl...	18 Years - 70 Years	Ain Shams University
Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis	NCT05502835	Intraoperative ... Hemodynamics Serum Lactate Intestinal Edem... Length of the H... First Time to G... Postoperative C...	pulse pressure ... conventional fl...	18 Years - 70 Years	Ain Shams University

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