Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Behaviors and Mental Disorders

Uterine Cervical Neoplasms

Pelvic Floor Disorders

Uterine Neoplasms

Genital Neoplasms, Female

Urogenital Neoplasms

Uterine Cervical Diseases

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Male Urogenital Diseases

Quality of Life

Assessment of the pelvic floor function

Questionnaires: EORTC, WHOQoL-BREF, PFID-20; PSIQ-12 and PFIQ-7.

Questionnaire application

Aline Ribeiro, MSc.

Aline Ribeiro, MSc

Harley Oliveira, PhD

Introduction: Pelvic floor muscle dysfunctions (PFMD) represent an important public health problem that manifests itself through lower urinary tract symptoms (LUTS), anorectal and sexual dysfunction. PFMD is a common problem in cervical cancer survivors (CC) with a negative impact on quality of life (QoL). Objective: This study aims to evaluate the effect of oncological treatment on the function of pelvic floor muscles (PFM) of survivors of CC. Methods: Patients diagnosed with CC, of any stage, histology and degree, accompanied by the Oncology Gynecology Service of the Hospital das Clínicas of the Medical School of Ribeirão Preto at the University of São Paulo, will be studied in the period between 2004 and 2014. Four study groups will be formed: (1) Patients with CC with PFMD; (2) Patients with CC without PFMD; : (3) Patients without CC with PFMD; (2) Patients without CC without PFMD. Non-cancer patients will be recruited into the community. For the analysis of the prevalence of PFMD will be applied to the discomfort Questionnaire on pelvic floor (IDPE-20) for evaluation of pelvic organ prolapse (POP) complaints, anorectal symptoms and urinary incontinence, and the Sexual Questionnaire for urinary incontinence and pelvic organ prolapse (PISQ -12) for evaluation of sexual function. Both questionnaires have already been validated for the Portuguese language and are specific for women with PFMD. The pelvic floor impact questionnaire (PFIQ-7) will also be applied to assess the impact of PFMD on quality of life, daily living activities and emotional health. For the evaluation of general QOL, the EORTC questionnaire QLQ-C30 and its specific module for patients with CC, QLQ-CX24 will be used. The evaluation of PFM function will include vaginal palpation (Modified Oxford Scale) and perineometry (Peritron).

Impact of Cancer Treatment on the Pelvic Floor Function in Survivors of Cervical Cancer

Evaluated through vaginal palpation and perineometry.

Evaluated through application of the questionnaire PFIQ-7.

Evaluated through application of the questionnaires PSIQ-12 and PFID-20.

Evaluated through application of the questionnaires EORTC QLQ-C30 and its specific module for patients with CC, QLQ-CX24 and the WHOQoL-BREF questionnaire.

University of Sao Paulo

MSc.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Impact of Cancer Treatment on the Pelvic Floor Function in Survivors of Cervical Cancer	NCT03188744	Cervical Cancer Pelvic Floor Di... Surgery Radiotherapy; C... Chemotherapy Ef...	Assessment of t... Questionnaire a...	-	University of Sao Paulo
Impact of Cancer Treatment on the Pelvic Floor Function in Survivors of Cervical Cancer	NCT03188744	Cervical Cancer Pelvic Floor Di... Surgery Radiotherapy; C... Chemotherapy Ef...	Assessment of t... Questionnaire a...	-	University of Sao Paulo

Spots Global Cancer Trial Database for questionnaire application