Spots Global Cancer Trial Database for chemotherapy effect
Every month we try and update this database with for chemotherapy effect cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Effectiveness of Mobile-health Self Management on Quality of Life of Patients Undergoing Chemotherapy | NCT05881070 | Cancer Chemotherapy Ef... Quality of Life Self Efficacy | Mobile-health s... | 20 Years - | Universitas Muhammadiyah Yogyakarta | |
| Immunotherapy and Chemotherapy in Unresectable Recurrent Loco-regionally Advanced Nasopharyngeal Carcinoma | NCT04921995 | Recurrent Nasop... Unresectable Na... Chemotherapy Ef... Immunotherapy Stereotactic Bo... | Tislelizumab | 15 Years - 90 Years | Fudan University | |
| Basal Tumours in Bladder Cancer, Response to chemoTherapy | NCT04089748 | Bladder Cancer Chemotherapy Ef... | neoadjuvant che... | 18 Years - 80 Years | University Hospital, Rouen | |
| Neoadjuvant Systemic and Peritoneal Chemotherapy for Advanced Gastric Cancer | NCT05318794 | Gastric Cancer Peritoneal Meta... Chemotherapy Ef... | Doxorubicin and... | - | Imperial College London | |
| Interest of Virtual Reality to Prevent Cancer Patient Anxiety Before Chemotherapy or an Invasive Act | NCT04419077 | Anxiety Chemotherapy Ef... Breast Cancer Head Cancer Nec... | Virtual reality... | 18 Years - | Hospices Civils de Lyon | |
| ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer | NCT05815082 | Colorectal Canc... Liver Metastase... Circulating Tum... Chemotherapy Ef... | Colorectal canc... FOLFOX chemothe... | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Definitive (Chemo)Radiotherapy for Patients With Esophageal Cancer - 3JECROG R-01 | NCT03298204 | Esophagus Cance... Chemoradiation Chemotherapy Ef... Radiotherapy Si... | 18 Years - | ChineseAMS | ||
| Potential Predictive Biomarkers in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer | NCT03532711 | Metastatic Colo... Chemotherapy Ef... Biomarker | fluorouracil | 18 Years - 80 Years | Fudan University | |
| EGFR Mutation Positive NSCLC Patients With Gefitinib and Thalidomide | NCT03341494 | NSCLC Stage IV Chemotherapy Ef... | Thalidomide | 18 Years - 70 Years | Fujian Cancer Hospital | |
| Salvage Chemotherapy Versus Total Mesorectal Resection for Local Resection Rectal Cancer Patients | NCT06043999 | Chemotherapy Ef... Rectal Cancer | Radical total m... Salavge Adjuvan... | 18 Years - 75 Years | Sun Yat-sen University | |
| Chemotherapy Oral Manifestations and Dental Awareness Among Parents | NCT05224882 | Mucositis Oral Chemotherapy Ef... | 1 Year - 14 Years | Cairo University | ||
| Diminish Chemotherapy Related Side Effects Through Patient Education | NCT04694794 | Chemotherapeuti... Chemotherapeuti... Chemotherapy Ef... | Educational Bro... | 18 Years - | Milton S. Hershey Medical Center | |
| Surufatinib Combined With Irinotecan as a Second-line Treatment for Small Cell Lung Cancer | NCT05595889 | Small Cell Lung... Angiogenesis Chemotherapy Ef... | Surufatinib Irinotecan | 18 Years - 80 Years | Fujian Cancer Hospital | |
| Topotecan and Melphalan for Retinoblastoma | NCT04799002 | Retinoblastoma Chemotherapy Ef... | Topotecan Melphalan | - | Sun Yat-sen University | |
| Application of Auricular Point Sticking in Patients With Taste Alteration | NCT05868850 | Dysgeusia Acupressure Chemotherapy Ef... | auricular point... | 18 Years - 85 Years | Affiliated Hospital of Jiangnan University | |
| COLONIC RESECTION FOR CANCER AS DIABETOGENIC RISK FACTOR | NCT04649567 | Glucose Metabol... Colon Cancer Surgery Chemotherapy Ef... | 18 Years - 100 Years | Hvidovre University Hospital | ||
| Evaluation of Response by FLT PET in Mesothelioma | NCT06410625 | Pleural Mesothe... Treatment Respo... Chemotherapy Ef... | FLT PET imaging | 18 Years - | Ankara University | |
| Simvastatin Effect in Combination With Neoadjuvant Chemotherapy to Clinical Response and Tumor-Free Margin in Locally Advanced Breast Cancer | NCT04418089 | Breast Cancer Chemotherapy Ef... | Simvastatin 40m... Placebo oral ca... | - | Indonesia University | |
| Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology | NCT03462524 | Esophageal Canc... Radiation Pneum... Pulmonary Fibro... Respiratory Fai... Pneumonia Surgery Chemotherapy Ef... Radiation Fibro... Radiation Toxic... Adenocarcinoma Squamous Cell C... | Esophagectomy | 18 Years - | St. James's Hospital, Ireland | |
| Intraperitoneal and System Chemotherapy Versus XELOX as First-line Chemotherapy for mCRC | NCT03792269 | Colorectal Canc... Chemotherapy Ef... Chemotherapeuti... | Irinotecan Oxaliplatin Capecitabine | 18 Years - | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | |
| Quantitative Nodal Burden as a Determinant Identifying Ampullary Adenocarcinoma Patients Benefiting From Adjuvant Chemotherapy | NCT06435767 | Ampullary Adeno... Chemotherapy Ef... | Adjuvant chemot... | 18 Years - 85 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| The Effect of the Art-based Mandala Intervention on the Quality of Life of Cancer Patients Receiving Chemotherapy | NCT05344820 | Cancer Chemotherapy Ef... Fatigue Quality of Life Rumination Alexithymia | Art based manda... | 18 Years - | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | |
| Autonomic Reflexes During Intra-arterial Chemotherapy for Retinoblastoma | NCT04451304 | Retinoblastoma Retinoblastoma ... Chemotherapy Ef... | - 18 Years | Federal University of São Paulo | ||
| Definitive (Chemo)Radiotherapy for Patients With Esophageal Cancer - 3JECROG R-01 | NCT03298204 | Esophagus Cance... Chemoradiation Chemotherapy Ef... Radiotherapy Si... | 18 Years - | ChineseAMS | ||
| Quantitative Nodal Burden as a Determinant Identifying Ampullary Adenocarcinoma Patients Benefiting From Adjuvant Chemotherapy | NCT06435767 | Ampullary Adeno... Chemotherapy Ef... | Adjuvant chemot... | 18 Years - 85 Years | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | |
| Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer | NCT06226857 | Colorectal Neop... Chemotherapy Ef... Molecular Seque... | Cetuximab | 18 Years - 99 Years | City Clinical Oncology Hospital No 1 | |
| Trabectedin/Caelyx vs Cisplatin Hypersensitivity in Relapsed Ovarian Cancer Patients Allergic to Platinum | NCT05512676 | Ovarian Neoplas... Chemotherapeuti... Chemotherapy Ef... Chemotherapy-in... Chemotherapy-in... | 18 Years - 80 Years | Oslo University Hospital | ||
| Tislelizumab Combined With Chemotherapy in the Treatment of Bone Metastases of Unknown Primary | NCT05241132 | Cancer of Unkno... Bone Cancer Met... Tislelizumab Gene Mutation-R... Immune Evasion,... Chemotherapy Ef... | Tislelizumab pl... | 18 Years - | Shanghai Changzheng Hospital | |
| Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies | NCT06376604 | Cancer, Ovarian Chemotherapy Ef... Calorie Deficie... Fasting, Interm... | Fasting Mimicki... Chemotherapy | 35 Years - 70 Years | L-Nutra Inc | |
| Improving Cognitive Function Through High-intensity Interval Training in Breast Cancer Patients Undergoing Chemotherapy | NCT04724499 | Breast Cancer Chemotherapy Ef... Exercise Therap... Cognitive Chang... | High-Intensity ... Attention Contr... | 18 Years - | Dana-Farber Cancer Institute | |
| Endoprosthesis Metal Toxicity Study | NCT04755140 | Bone Tumor Cancer of Bone Heart Diseases Cognitive Impai... Cognitive Decli... Chemotherapy Ef... Memory Problem | Questionnaires Interviews Blood Test Echocardiogram | 18 Years - 100 Years | Mayo Clinic | |
| Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric Cancer | NCT03229096 | Chemotherapy Ef... Chemotherapeuti... Gastric Cancer | Apatinib plus X... | 18 Years - 75 Years | Shanghai Zhongshan Hospital | |
| HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden. | NCT04898504 | Colorectal Canc... Liver Metastase... Chemotherapy Ef... | Floxuridine Liver Transplan... | 18 Years - | Oslo University Hospital | |
| Efficacy of Supplement Adjuvant Capecitabine in HR+/HER2- Breast Cancer Patients With High Risks | NCT05212454 | Breast Cancer Chemotherapy Ef... | Capecitabine | 18 Years - 70 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University | |
| Concurrent FOLFIRINOX Plus High Intensity Focused Ultrasound for Pancreatic Cancer | NCT05262452 | Pancreatic Canc... Chemotherapy Ef... Ultrasound Ther... | ALPIUS 900, an ... FOLFIRINOX regi... | 19 Years - 85 Years | Seoul National University Hospital | |
| Endoprosthesis Metal Toxicity Study | NCT04755140 | Bone Tumor Cancer of Bone Heart Diseases Cognitive Impai... Cognitive Decli... Chemotherapy Ef... Memory Problem | Questionnaires Interviews Blood Test Echocardiogram | 18 Years - 100 Years | Mayo Clinic | |
| EGFR Mutation Positive NSCLC Patients With Gefitinib and Thalidomide | NCT03341494 | NSCLC Stage IV Chemotherapy Ef... | Thalidomide | 18 Years - 70 Years | Fujian Cancer Hospital | |
| Mutation Scores and Differential Protein Evaluating Efficacy in Adjuvant Chemotherapy in HER2(-) Luminal B Breast Cancer | NCT03359694 | Susceptibility,... Chemotherapy Ef... | DT group ET group NX group | 18 Years - 70 Years | Tianjin Medical University Cancer Institute and Hospital | |
| Endoprosthesis Metal Toxicity Study | NCT04755140 | Bone Tumor Cancer of Bone Heart Diseases Cognitive Impai... Cognitive Decli... Chemotherapy Ef... Memory Problem | Questionnaires Interviews Blood Test Echocardiogram | 18 Years - 100 Years | Mayo Clinic | |
| A Multi-center, Non-randomized, Open-label Phase II Clinical Study on the Treatment of Newly Diagnosed Advanced Hodgkin's Lymphoma With PD-1 Antibody (Tislelizumab) Combined With AVD Regimen (Doxorubicin, Vindesine, Dacarbazine) Under the Guidance of PET/CT | NCT04843267 | Hodgkin Lymphom... Chemotherapy Ef... | Tislelizumab | 18 Years - 80 Years | Sun Yat-sen University | |
| Evaluating Xihuang Pill to Improve the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer | NCT05914753 | Breast Cancer Chemotherapy Ef... | Epirubicin, Cyc... Epirubicin, Cyc... | 18 Years - 80 Years | Zhejiang Provincial People's Hospital | |
| The Effect of Gemcitabine Plus Nab-paclitaxel as Secondary Chemotherapy in Advanced Pancreatic Cancer | NCT03401827 | Pancreatic Aden... Chemotherapy Ef... | Chemotherapy (G... | 20 Years - | Seoul National University Hospital | |
| Dragon III-Phase 3: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer | NCT04384601 | Gastric Cancer Neoadjuvant Che... | Chemotherapy | 18 Years - 80 Years | Ruijin Hospital | |
| Culturally Tailored Nurse Coaching Study for Cancer Symptom Management | NCT04874584 | Dehydration Symptom Cluster Quality of Life Self Efficacy Chemotherapy Ef... | CTNSM Standard of Car... | 18 Years - | University of Miami | |
| Unnecessary Mastectomy Due to False Size Prediction by Preoperative Imaging Studies in Breast Cancer | NCT04689529 | Breast Cancer Surgery IMAGE Chemotherapy Ef... | Preoperative im... | 20 Years - | Seoul National University Hospital | |
| Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model | NCT05289076 | Colorectal Canc... Tumour Metastas... Chemotherapy Ef... Tumor Growth | Chemotherapy dr... | 18 Years - | University Hospital, Linkoeping | |
| Development of Biomarker for the Evaluation of Response After Neoadjuvant Therapy in Patients With Pancreatic Cancer | NCT04110769 | Genetic Change Chemotherapy Ef... Pancreatic Canc... | next generation... following next ... | 20 Years - | Asan Medical Center | |
| Prevention of Paclitaxel-induced Neuropathic Pain in Patients With Planned Paclitaxel Chemotherapy (PrevTel) | NCT05322889 | Neuropathic Pai... Chemotherapy Ef... | Telmisartan tab... | 18 Years - 80 Years | Fraunhofer Institute for Molecular Biology and Applied Ecology | |
| Role of the ATP7A Transporter in Ovarian Cancer | NCT05490407 | Gynecologic Can... Ovarian Cancer High Grade Sero... Chemotherapy Ef... | Carboplatin | 18 Years - 80 Years | University Medical Centre Ljubljana | |
| Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer | NCT03975049 | Rectal Cancer Chemotherapy Ef... | Chemoradiation FOLFOXIRI Proto... Folfox Protocol | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma | NCT06140732 | Chordoma Chemotherapy Ef... | camrelizumab an... | 18 Years - | Xuanwu Hospital, Beijing | |
| Effectiveness of Mobile-health Self Management on Quality of Life of Patients Undergoing Chemotherapy | NCT05881070 | Cancer Chemotherapy Ef... Quality of Life Self Efficacy | Mobile-health s... | 20 Years - | Universitas Muhammadiyah Yogyakarta | |
| Pembrolizumab Plus Chemotherapy in 1st Line Treatment of Pancreatic Cancer | NCT04447092 | Pancreatic Canc... Chemotherapy Ef... | Gemcitabine Nab-paclitaxel Pembrolizumab Oxaliplatin Leucovorin Irinotecan 5FU | 18 Years - | Seoul National University Hospital | |
| Effect on Adaptation to Cancer of Mobile Application Developed for Gynecological Cancer Patients | NCT05131490 | Gynecologic Can... Chemotherapy Ef... Mobile Applicat... Physiological A... Psychosocial Ad... | A mobile applic... | 18 Years - | Pamukkale University | |
| GS Regimen as the First-line Chemotherapy in Chinese Advanced PC Patients | NCT03869294 | Pancreatic Canc... Chemotherapy Ef... Chemotherapeuti... | GS | 18 Years - 80 Years | Zhejiang University | |
| The Maintenance Regimen and Revised Regimen for Advanced Breast Cancer Survivors After First-line Salvage Therapy | NCT03423849 | Breast Cancer Chemotherapy Ef... Disease-free Su... | Vinorelbine Gemcitabine Cisplatin Capecitabine | 18 Years - 70 Years | Shandong Cancer Hospital and Institute | |
| Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer | NCT06047158 | Fish Oils Perfusion; Comp... Stomach Neoplas... Nutrition Aspec... Chemotherapy Ef... Immunisation Re... | Omega-3 fish oi... | 18 Years - 75 Years | The Affiliated Hospital of Qingdao University | |
| Impact of Cancer Treatment on the Pelvic Floor Function in Survivors of Cervical Cancer | NCT03188744 | Cervical Cancer Pelvic Floor Di... Surgery Radiotherapy; C... Chemotherapy Ef... | Assessment of t... Questionnaire a... | - | University of Sao Paulo | |
| Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients | NCT05797467 | Colorectal Canc... Chemotherapy Ef... | FOLFOX chemothe... Bevacizumab | 18 Years - 75 Years | Sixth Affiliated Hospital, Sun Yat-sen University | |
| CAncer, NUtrition and Taste - Validation of the CANUT-QVA Questionnaire on Eating Habits in Cancer Patients | NCT04235153 | Hematologic Can... Undernutrition Chemotherapy Ef... Taste Disorders Chemotherapy-In... Olfactory Disor... | Evaluation of t... | 18 Years - | Hospices Civils de Lyon | |
| Toripalimab and Gemcitabine in Recurrent or Metastatic Nasopharyngeal Carcinoma. | NCT04405622 | Nasopharyngeal ... Recurrent Nasop... Metastatic Naso... Chemotherapy Ef... Immunotherapy | Toripalimab plu... | 18 Years - 70 Years | Sun Yat-sen University | |
| Home-Combo: an Online Home-based Combined Exercise Intervention for Women With Breast Cancer | NCT06429189 | Breast Cancer Chemotherapy Ef... | Home-based comb... | 18 Years - | Grupo Lusófona | |
| Prevention and Treatment of Complications of Endovascular Methods in Patients With Malignant Liver Tumors | NCT04764409 | Hepatic Cancer Metastatic Canc... Chemotherapy Ef... | Chemoembolizati... Chemoinfusion | 18 Years - | Central Clinical Hospital RZD-Medicine, Russian Federation | |
| Sintilimab Combined With Modified FLOT Regimen in the Treatment of Metastatic Gastric Cancer | NCT05982301 | Gastric Cancer Chemotherapy Ef... Immune Checkpoi... | Sintilimab, pac... | 18 Years - | Fudan University | |
| Effect of Spironolactone in the Prevention of Anthracycline-induced Cardiotoxicity (SPIROTOX) | NCT06005259 | Cardiotoxicity Neoplasms Chemotherapy Ef... Heart Failure | Spironolactone Placebo | 18 Years - | University of Sao Paulo | |
| Rituximab Combined With Chidamide and Lenalidomide for r/r AITL | NCT04319601 | Angioimmunoblas... Chemotherapy Ef... Chemotherapeuti... | Rituximab | 18 Years - 70 Years | Zhejiang Cancer Hospital | |
| HAI-Floxuridine, or SIRT, Combined With Gemox For Patients With Intra-Hepatic Cholangiocarcinoma Not Amenable to Resection (TOMCAT) | NCT06313203 | Intrahepatic Ch... Chemotherapy Ef... | Floxuridine Selective Inter... | 18 Years - | Oslo University Hospital | |
| Effectiveness of Immersive Virtual Reality in Patients With Cancer | NCT05629507 | Cancer Chemotherapy Ef... Anxiety Fatigue Pain | Virtual Reality | 18 Years - | ASL Gallura - Ospedale Giovanni Paolo II | |
| Pembrolizumab Plus Chemotherapy in 1st Line Treatment of Pancreatic Cancer | NCT04447092 | Pancreatic Canc... Chemotherapy Ef... | Gemcitabine Nab-paclitaxel Pembrolizumab Oxaliplatin Leucovorin Irinotecan 5FU | 18 Years - | Seoul National University Hospital | |
| FOcus on Reducing Dose-limiting Toxicities in Colon Cancer With Resistance Exercise Study | NCT03291951 | Resistance Trai... Colon Cancer Chemotherapy Ef... | Resistance trai... | 18 Years - | Kaiser Permanente | |
| Comparative Study of Lobaplatin and Paclitaxel in Advanced Gastric Cancer Patients With D2 Surgery Combined With Hyperthermic Intraperitoneal Chemotherapy | NCT04808466 | Gastric Cancer Chemotherapy Ef... Surgery Metastasis Survival | Paclitaxel Lobaplatin | 18 Years - 75 Years | Wuhan Union Hospital, China | |
| Neoadjuvant Chemo-hormonal Therapy Combined With Radical Prostatectomy for Locally Advanced Prostate Cancer | NCT04220398 | Prostate Cancer Chemotherapy Ef... Hormone Sensiti... Locally Advance... | Neoadjuvant che... Neoadjuvant hor... Radical Prostat... | 18 Years - 75 Years | RenJi Hospital | |
| Infusional FOLFOX Plus Camrelizumab and Apatinib vs HAIC-FOLFOX Plus Camrelizumab and Apatinib for Advanced HCC | NCT06172205 | BCLC Stage C He... Chemotherapy Ef... | intravenous FOL... HAIC-FOLFOX plu... | 18 Years - 75 Years | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | |
| Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies | NCT06376604 | Cancer, Ovarian Chemotherapy Ef... Calorie Deficie... Fasting, Interm... | Fasting Mimicki... Chemotherapy | 35 Years - 70 Years | L-Nutra Inc | |
| Evaluation of the Impact of Chemotherapy on Body Odor in Adolescents and Young Adults in Oncology | NCT04899505 | Solid Tumor, Ad... Solid Tumor, Ch... Chemotherapy Ef... | Evaluation on a... | 15 Years - 25 Years | Institut Curie | |
| The Efficacy and Safety of Docetaxel Combined With Platinum for Metastatic Hormone-sensitive Prostate Cancer | NCT05461261 | Hormone Sensiti... DNA Damage Repa... Chemotherapy Ef... Chemotherapeuti... | Docetaxel Prednisolone Ac... Platinum-based ... | 40 Years - 75 Years | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | |
| Needs Assessment of Cancer Patients With Complementary and Alternative Medicines | NCT03954509 | Cancer Chemotherapy Ef... | 18 Years - | Fondation Hôpital Saint-Joseph | ||
| A Study of Postoperative Adjuvant Chemotherapy for Upper Urinary Urothelial Carcinoma With Lymphovascular Invasion | NCT04255771 | Chemotherapy Ef... | Gemcitabine Placebos | 20 Years - 85 Years | Shandong Provincial Hospital | |
| Measuring the Impact of Onco4D® Guidance on Chemotherapy Selection and Outcomes | NCT04891952 | Cancer Chemotherapy Ef... | Onco4D Biodynam... | - | Animated Dynamics, Inc. | |
| Efficacy of Supplement Adjuvant Capecitabine in HR+/HER2- Breast Cancer Patients With High Risks | NCT05212454 | Breast Cancer Chemotherapy Ef... | Capecitabine | 18 Years - 70 Years | Second Affiliated Hospital, School of Medicine, Zhejiang University |
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